Xenbase Image ID: 83828

Fig. 2. XSmo induces ectopic otic vesicles expressing XPax-2. Embryos injected with XSmo mRNA (1.5 ng) into one of two blastomeres were fixed at embryonic stage 36 and stained for XPax-2 expression (purple) by whole-mount in situ hybridization. Lateral (A�C, E) and dorsolateral (D) views of injected embryos showing ectopic vesicular structures expressing XPax-2 in -galactosidase-positive (light blue) manipulated sides (arrowheads, 12%, n 50). (F) Horizontal vibratome section of the embryo shown in (D) at the level of the otic vesicles revealing the vesicular morphology of the ectopic otic vesicle. The single otic vesicle of the noninjected side appeared in a section plane localized more ventrally (not shown). Fig. Image published in: Koebernick K et al. (2003) Copyright © 2003. Image reproduced with permission of the Publisher, Elsevier B. V. Gene Synonyms Species Stage(s) Tissue pax2.L LOC108697493, pax-2, pax2-a, pax2-b, XPax-2, XPax2 X. laevis Throughout NF stage 35 and 36 otic vesicle midbrain-hindbrain boundary optic stalk Image source: Published Larger Image Printer Friendly View

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