Xenbase Image ID: 83830

Fig. 4. Effects of mHIP on XPtc1 expression and otic specification. Following injection of mHIP mRNA (750 pg) into one of two blastomeres, embryos were fixed at stage 38 (A) or stage 36 (B-G) and stained for expression of XPtc1 (A), Xdll-3 (B-E), or XPax-2 (F, G). mHIP-injected embryos (n 24) exhibit strongly reduced XPtc1 expression (74%; A). In parallel, ectopic vesicular structures (depicted by triangles) expressing Xdll-3 (27%, n 22) and XPax-2 (10%, n 31) were also observed in mHIP-injected embryos. is, injected side; nis, noninjected side. Image published in: Koebernick K et al. (2003) Copyright © 2003. Image reproduced with permission of the Publisher, Elsevier B. V. Gene Synonyms Species Stage(s) Tissue ptch1.S patched, patched1, Ptc-1, Ptc1, X-ptc1, XPtc1 X. laevis Throughout NF stage 37 and 38 otic vesicle midbrain-hindbrain boundary pharyngeal arch mandibular arch hyoid arch branchial arch mesoderm foregut pax2.L LOC108697493, pax-2, pax2-a, pax2-b, XPax-2, XPax2 X. laevis Throughout NF stage 35 and 36 otic vesicle pronephric kidney pronephric tubule central nervous system brain spinal cord pronephric duct Image source: Published Larger Image Printer Friendly View

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