Xenbase Image ID: 83998

Fig. 3. Expression pattern of axial and paraxial markers in Oct25 mRNA injected embryos show axis formation defects. Shown are dor- sal to dorso-vegetal views of the mesodermal marker Xbra, the axial protocadherin AXPC, the axial marker Chd, the paraxial PAPC, and the paraxial expression of the early muscle marker MyoD. (A-E) Expression of these markers in uninjected embryos at the late gastrula stage 12. (F-J) Corresponding expression in embryos injected with Oct25 mRNA in the animal pole. (K-O) Expression of these markers in uninjected embryos at stages that have a similar blastopore size as the Oct25 mRNA injected embryos. Appendant values are listed in Table S3. Image published in: Julier A et al. (2012) Copyright © 2012. Image reproduced with permission of the Publisher, John Wiley & Sons. Gene Synonyms Species Stage(s) Tissue tbxt.S bra, brachyury, ntl, t, t-a, t-b, X-bra, Xbra, Xbrachyury X. laevis Throughout NF stage 10.5 marginal zone tbxt.S bra, brachyury, ntl, t, t-a, t-b, X-bra, Xbra, Xbrachyury X. laevis Throughout NF stage 12 marginal zone presumptive axial mesoderm pcdh1.L axial protocadherin, axpc X. laevis Throughout NF stage 10.5 dorsal marginal zone pcdh1.L axial protocadherin, axpc X. laevis Throughout NF stage 12 presumptive axial mesoderm chrd.S chd, chordin, chrd.1, LOC108716939, X-chordin X. laevis Throughout NF stage 10.5 dorsal marginal zone upper blastopore lip chrd.S chd, chordin, chrd.1, LOC108716939, X-chordin X. laevis Throughout NF stage 12 presumptive axial mesoderm neural plate pcdh8.2.L arcadlin, papc X. laevis Throughout NF stage 10.5 dorsal marginal zone pcdh8.2.L arcadlin, papc X. laevis Throughout NF stage 12 presumptive paraxial mesoderm myod1.S mf25, MyoD, myod1-a, myod1-b, myogenic factor 3, XMyoD, XtmyoD X. laevis Throughout NF stage 10.5 dorso-lateral marginal zone myod1.S mf25, MyoD, myod1-a, myod1-b, myogenic factor 3, XMyoD, XtmyoD X. laevis Throughout NF stage 12 presumptive paraxial mesoderm Image source: Published Experiment + Assay Source Phenotypes and Disease Xla Wt + pou5f3.2 + NF12 (in situ hybridization) fig.3. f Expression Phenotype decreased amount tbxt.S expression in axial region Xla Wt + pou5f3.2 + NF12 (morphology) fig.3. f-j Anatomical Phenotype abnormal gastrulation abnormally delayed closure of blastopore Larger Image Printer Friendly View

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