Xenbase Image ID: 84155

Figure 2. A Combination of Genetic Approaches to Investigate miRNA Function in Xenopus Embryos Schematic diagram summarizing the different approaches used to show that miR-142-3p is necessary and sufficient for hemangioblast specification during establishment of the HSC lineage. A combination of loss-of-function (LOF), gain-of-function (GOF), and rescue experiments were used to investigate whether miR-142-3p controls definitive hemangioblast specification. Image published in: Nimmo R et al. (2013) Copyright © 2013. Image reproduced with permission of the Publisher, Elsevier B. V. Larger Image Printer Friendly View

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