XB-IMG-84177
Xenbase Image ID: 84177
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Figure 7. mZac1c promotes apoptosis in Xenopus retina at stage 32. A�F: Stage 32 control green fluorescent protein (GFP, A�C) and Zac1+GFP�injected (D�F) retinae labeled with anti�activated caspase-3 (ac-3, red, A,C,D,F) and GFP epifluorescence (green, B,C,E,F). The insert in F shows a high-magnification image, and arrowheads in F show GFP/ac-3 double positive cells. G�I: Stage 40 Zac1+GFP�injected retinae labeled with ac-3 (red, G,I) and GFP epifluorescence (green, H, I). J: Quantification of apoptotic control and Zac1-misexpressing cells in stage 32 retinae. n refers to the number of retinae examined, and total cells counted were control (n = 2,115) and Zac1 (n = 1,705). Error bars are SEM. *P < 0.05. gcl, ganglion cell layer; inl, inner nuclear layer; onl, outer nuclear layer; vz, ventricular zone. Image published in: Ma L et al. (2007) Copyright © 2007. Image reproduced with permission of the Publisher, John Wiley & Sons.
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