Xenbase Image ID: 84499

Fig. 4. Goblet cells in the Xenopus epidermis secrete Intelectin-2. (A) A Xenopus epidermis goblet cell; membrane-GFP (green) reveals the extensive exocytic vesicles; antibody staining demonstrates the presence of intelectin-2 (red) in these vesicles. Arrows mark vesicles absent of intelectin-2. (B–B′) High magnification of exocytic vesicles shown in panel A. (C–E) Transmission electron microscopy of a Xenopus epidermis goblet cell. (C) Three apically located vesicles at different stages of exocytosis are visible in an epidermal goblet cell. A mucus granule can be seen in the process of being secreted. (D) Membrane fusion intermediate during exocytosis. (E) Exocytic release. Image published in: Hayes JM et al. (2007) Copyright © 2007. Image reproduced with permission of the Publisher, Elsevier B. V. Gene Synonyms Species Stage(s) Tissue itln2.L hl-2, hl2, intel 2, intel2, intelectin-2, Xeel X. laevis Sometime during NF stage 29 and 30 to NF stage 35 and 36 epidermis goblet cell mucociliary epithelium non-ciliated epithelial cell Image source: Published Larger Image Printer Friendly View

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