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XB-IMG-84644

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Figure 2. ETO2 Is Specifically Required for the Establishment of the Hematopoietic Program in the DA(A) Notch1 is absent in the DA of Eto2-MO and Eto2-MO2 morphants (stages 35/36/39, WMISH, and stage 39 bottom, ISHS; red arrowheads, DA; orange arrowheads, notochord).(B and C) Expression analysis of arterial-affiliated genes EphrinB2, Delta-like4 (Dll4), and Notch4 (B), as well as Gata2 (C) in the presumptive DA (stage 32) and in the DA (stages 34–39) in Eto2 morphants, red arrowheads. White and orange arrowheads: neural tube and notochord, respectively.Numbers in the bottom of the panels denote the number of embryos as shown in the panel out of the total examined. Whole mounts are shown with anterior to the left and dorsal to the top. Sections are in transverse orientation with dorsal to the top. See also Figures S2A and S4.

Image published in: Leung A et al. (2013)

Image downloaded from an Open Access article in PubMed Central. © 2013 ELL & Excerpta Medica.

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