Xenbase Image ID: 86655

Coco knockdown in the ventral-right blastomere results in right-sided Xnr1 induction in the LPM. Embryos were coinjected with β-Gal lineage tracer and Coco-MO1/2 into defined regions of the dorsal or ventral right blastomere at the four-cell stage, cultured until Stage 22, and processed for Xnr1 WMISH. (a-c) Representative specimens of dorsal-lateral (a), ventral-lateral (b), and ventral-central (c) injections, which resulted in ectopic induction of Xnr1 in the right LPM. Histological sections (a′-c′; planes indicated by dashed lines in a-c) and higher magnifications (a′-c′; region indicated by dashed rectangle in a′-c′) demonstrate Rose-Gal positive cells in the somites in all cases (outlined and marked with 's'). Notochord (N), somites (S), and lateral plate mesoderm (LPM) outlined by dashed lines in (a′-c′). Image published in: Tingler M et al. (2014) Copyright © 2014. Image reproduced with permission of the Publisher, John Wiley & Sons. Larger Image Printer Friendly View

Return to previous page