Xenbase Image ID: 86701

Figure S1: dhrs3 has the similar effect of cyp26a1 on neuroectoderm patterning. At 4-cell stage, one dorsal blastomere of the embryo was injected with different combinations of 2 ng cyp26a1 or 4 ng dhrs3, together with 100 pg LacZ as lineage tracer. Whole mount in situ hybridization was done at stage 19. Injected side is on the right (asterisk). (A, B) expression of en2, krox20, and foxd3 in control embryos. (C-F) overexpression of cyp26a1 or dhrs3 causes posterior shift of en2 and krox20 expression. Similar trend was observed for neural crest marker foxd3 (white dashed line). Image published in: Kam RK et al. (2013) Copyright © 2013. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Gene Synonyms Species Stage(s) Tissue en2.L En-2, en2-a, en2-b, eng2, engrailed 2, engrailed homolog 2, engrailed-2, maben, xen2 X. laevis Throughout NF stage 19 presumptive midbrain-hindbrain boundary egr2.L EGR-2, Krox-20, krox20, XKr20, XKrox-20 X. laevis Throughout NF stage 19 rhombomere rhombomere R3 rhombomere R5 foxd3.L fkh6, foxd3-a, foxd3-b, XFD-6, xfoxd3 X. laevis Throughout NF stage 19 neural crest cranial neural crest Image source: Published Larger Image Printer Friendly View

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