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XB-IMG-86750

Xenbase Image ID: 86750


Figure 1. A: Lateral view of a whole-mount brain of a Xenopus embryo at stage 33–34, hybridized for xDll4. The red dashed lines represent the horizontal section plane and level of the sections shown in panels B–L (a, telencephalic level, similar to those shown in panels B–E and I–J; b, section through the preoptic region [PO] and eminentia thalami [ET], similar to those shown in F–H and K–L). B: Schema of a horizontal section through the embryonic telencephalon of Xenopus showing the major telencephalic divisions based on the gene expression patterns shown in panels C–E. C–E,I,J: Horizontal sections through the telencephalon of Xenopus embryos at stages 33–34 (E), 35–36 (C,D), or 37–38 (I,J), hybridized for xEomes (C,I), xEmx1 (D,J) or xDll4 (E). Note the broad expression of xEomes in the pallium (P; in proliferating and postmitotic cells), which is complementary to that of xDll4 in the subpallium (SP; C,E). xEmx1 is also broadly expressed in the majority of the pallium, except for a ventral pallial area (ventral pallium or VP) that contains only xEmx1-expressing cells in the mantle (D, J). The ventral pallium shows the strongest xEomes expression (C,I). In addition to the expression of xEomes and xEmx1 in the pallium, signal of these genes is observed in the subpallial mantle and may represent immigrant cells coming from the pallium. F–H,K,L: Horizontal sections through the PO and ET of Xenopus embryos at stages 33–34 (H), 35–36 (F,G), or 37–38 (K,L), hybridized for xEomes (F,K), xEmx1 (G,L), or xDll4 (H). Note the strong expression of pallial marker genes in the ET and the absence of xDll4 expression in this region. Asterisks in J and L represent an artifact. See text for more details. For abbreviations , see list. Scale bars = 100 μm in A; 50 μm in C (applies to C–L).

Image published in: Brox A et al. (2004)

Copyright © 2004. Image reproduced with permission of the Publisher, John Wiley & Sons.

GeneSynonymsSpeciesStage(s)Tissue
dlx2.Ltes-1, tes1, X-dll4, Xdll4X. laevisThroughout NF stage 33 and 34telencephalon
subpallium
thalamus
preoptic area
hypothalamus
diencephalon
forebrain
brain
eomes.Leomesodermin, tbr2, xeomesX. laevisThroughout NF stage 35 and 36telencephalon
eminentia thalami
ventral pallium
forebrain
brain
eomes.Leomesodermin, tbr2, xeomesX. laevisThroughout NF stage 37 and 38telencephalon
eminentia thalami
ventral pallium
forebrain
brain
emx1l.LXemx1X. laevisThroughout NF stage 35 and 36telencephalon
pallium
ventral pallium
eminentia thalami
preoptic area
brain
forebrain
emx1l.LXemx1X. laevisThroughout NF stage 37 and 38telencephalon
subpallium
pallium
brain
eminentia thalami
ventral pallium
forebrain

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