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Fig. 6. AWP1 is involved in Wnt/􀁠-catenin signaling. (A) Four-cell stage embryos were injected in the animal pole region with the indicated combinations of 􀁠-catenin-myc (100 pg), Co MO (40 ng), AWP1 MO1 (40 ng), hAWP1 (400 pg) and XAWP1 (400 pg), and the animal caps were excised at stage 9 and cultured to stage 11 for western blotting. (B) HEK 293T cell were transfected as indicated with 􀀶N LRP6 (450 ng), XDsh (450 ng), AWP1 siRNA (50 nM) and Co siRNA (50 nM). Three independent experiments were performed and a single representative result is shown. Error bars denote standard deviations.

Image published in: Seo JH et al. (2013)

Copyright © 2013. Reproduced with permission of the Publisher, University of the Basque Country Press.

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