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Fig. 4. Molecular markers of the inner ear in sp8 MO- or TALEN-injected embryos. (A–J) Expression patterns of krox20, epha4, mafb, gbx2, and foxj1.2 in uninjected and sp8 TALEN- or MO-injected embryos. Arrows, uninjected side. Arrowheads, injected side. Anterior is up. (K–T) Expression domains of pax2, msx1, tbx1, sox2, and oc90 in WT and mutant embryos at stage 33/34. Image published in: Chung HA et al. (2014) Copyright © 2014. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Gene Synonyms Species Stage(s) Tissue egr2 EGR-2, Krox-20, krox20, XKr20, XKrox-20 X. tropicalis Throughout NF stage 18 otic placode presumptive rhombomere epha4 eph-a4, epha4-a, epha4-b, hek8, Pag, Pagliaccio, rtk1, sek, sek-1, tyr01, XEpha4 X. tropicalis Throughout NF stage 18 otic placode presumptive rhombomere mafb kreisler, valentino, xmafb X. tropicalis Throughout NF stage 18 presumptive rhombomere otic placode gbx2.2 XGBX-2 X. tropicalis Throughout NF stage 18 neural plate border presumptive midbrain-hindbrain boundary anterior placodal area otic placode foxj1.2 X. tropicalis Throughout NF stage 18 neural plate otic placode pax2 LOC108697493, pax-2, pax2-a, pax2-b, XPax-2, XPax2 X. tropicalis Throughout NF stage 33 and 34 otic vesicle brain msx1 hox-7, hox7, msx-1, msx1-a, msx1-b, Xhox-7.1, Xmsx-1, xmsx1 X. tropicalis Throughout NF stage 33 and 34 otic vesicle brain tbx1 cafs, cthm, dgcr, dorv, tbx1-a, tbx1-b, tbx1c, vcfs, xtbx1 X. tropicalis Throughout NF stage 33 and 34 otic vesicle sox2 anop3, LOC108718087, mcops3, Sox-2, XLSOX-2, Xsox-2, XSox2 X. tropicalis Throughout NF stage 33 and 34 otic vesicle brain head cranial ganglion eye oc90 otoconin 90 X. tropicalis Throughout NF stage 33 and 34 otic vesicle Image source: Published Larger Image Printer Friendly View

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