Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
Summary Literature (2)
DOID:0050424 - familial adenomatous polyposis


Disease Ontology Definition:An intestinal disease that has_material_basis_in mutations in the APC gene and involves formation of numerous polyps in the epithelium of the large intestine which are initially benign and later transform into colon cancer.

Synonyms: adenomatous polyposis of the colon

Referenced OMIM:
OMIM:175100 - FAMILIAL ADENOMATOUS POLYPOSIS 1; FAP1
OMIM:608456 - FAMILIAL ADENOMATOUS POLYPOSIS 2; FAP2

Human Disease Resources: Disease Ontology, EMBL-EBI, OLSVis tree view, Ontobee

Xenbase Genes : apc, nthl1, mutyh, msh3

Other Model Organisms: AGR, MGI, ZFIN, FlyBase, WormBase, RGD
Parent(s): autosomal dominant disease (is_a), autosomal genetic disease (is_a), intestinal disease (is_a)


Xenbase: The Xenopus Model Organism Knowledgebase.
Version: 4.15.0
Major funding for Xenbase is provided by grant P41 HD064556