Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
Summary Literature (0)
DOID:0050786 - iridogoniodysgenesis syndrome


Disease Ontology Definition:An autosomal dominant disease that is characterized by the iris stroma being hypoplastic resulting from abnormalities in the differentiation of the anterior segment structures and increased values of intraocular pressure and has_material_basis_in autosomal dominant inheritance of mutations in the PITX2 gene.

Synonyms: IGDS; IRID 1; IRID 2; iridogoniodysgenesis type 1; iridogoniodysgenesis type 2

Referenced OMIM:
OMIM:137600 - ANTERIOR SEGMENT DYSGENESIS 4; ASGD4
OMIM:601631 - ANTERIOR SEGMENT DYSGENESIS 3; ASGD3

Human Disease Resources: Disease Ontology, EMBL-EBI, OLSVis tree view, Ontobee

Xenbase Genes : foxc1, pitx2

Other Model Organisms: AGR, MGI, ZFIN, FlyBase, WormBase, RGD
Parent(s): autosomal dominant disease (is_a)


Xenbase: The Xenopus laevis and X. tropicalis resource.
Version: 4.11.3


Major funding for Xenbase is provided by grant P41 HD064556