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Summary Literature (0)
DOID:3652 - Leigh disease


Disease Ontology Definition:A mitochondrial metabolism disease characterized by progressive loss of mental and movement abilities. Symptoms usually begin between ages of three months and two years and include loss of appetite, vomiting, irritability and seizure activity.

Synonyms: Infantile necrotizing encephalomyelopathy, Leigh syndrome, juvenile subacute necrotizing encephalomyelopathy, subacute necrotizing encephalomyelopathy

Referenced OMIM:
OMIM:220111 - LEIGH SYNDROME, FRENCH CANADIAN TYPE; LSFC
OMIM:256000 - LEIGH SYNDROME; LS

Human Disease Resources: Disease Ontology, EMBL-EBI, OLSVis tree view, Ontobee

Xenbase Genes : ndufv1, ndufs8, ndufs4, ndufa2, ndufa10, ndufa9, cox10, sdha, ndufaf6, dld, cox15, ndufs3, ndufs7, lrpprc, bcs1l, [+]

Other Model Organisms: AGR, MGI, ZFIN, FlyBase, WormBase, RGD
Parent(s): mitochondrial metabolism disease (is_a)


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