Summary Literature (1113)

Xenbase Articles :
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Subthreshold changes of voltage-dependent activation of the K(V)7.2 channel in neonatal epilepsy., Hunter J,Maljevic S,Shankar A,Siegel A,Weissman B,Holt P,Olson L,Lerche H,Escayg A, Neurobiol Dis. October 1, 2006; 24(1):1095-953X.

The Na+:Cl- cotransporter is activated and phosphorylated at the amino-terminal domain upon intracellular chloride depletion., Pacheco-Alvarez D,Cristóbal PS,Meade P,Moreno E,Vazquez N,Muñoz E,Díaz A,Juárez ME,Giménez I,Gamba G, J Biol Chem. September 29, 2006; 281(39):1083-351X.

Characterization of atrazine-induced gonadal malformations in African clawed frogs (Xenopus laevis) and comparisons with effects of an androgen antagonist (cyproterone acetate) and exogenous estrogen (17beta-estradiol): Support for the demasculinization/feminization hypothesis., Hayes TB,Stuart AA,Mendoza M,Collins A,Noriega N,Vonk A,Johnston G,Liu R,Kpodzo D, Environ Health Perspect. April 1, 2006; 114 Suppl 1(Suppl 1):0091-6765.

Transforming growth factor beta signaling, vascular remodeling, and hypertension., August P,Suthanthiran M, N Engl J Med. June 22, 2006; 354(25):1533-4406.

Introduction to nucleocytoplasmic transport: molecules and mechanisms., Peters R, Methods Mol Biol. January 1, 2006; 322:1940-6029.

Negative regulation of Hedgehog signaling by the cholesterogenic enzyme 7-dehydrocholesterol reductase., Koide T,Hayata T,Cho KW, Development. June 1, 2006; 133(12):1477-9129.

The Wnt-dependent signaling pathways as target in oncology drug discovery., Janssens N,Janicot M,Perera T, Invest New Drugs. July 1, 2006; 24(4):0167-6997.

Effects of the abused inhalant toluene on ethanol-sensitive potassium channels expressed in oocytes., Del Re AM,Dopico AM,Woodward JJ, Dev Biol. May 4, 2006; 1087(1):0012-1606.

Fishing and frogging for anti-angiogenic drugs., De Smet F,Carmeliet P,Autiero M, Nat Chem Biol. May 1, 2006; 2(5):1552-4469.

Coupling modes and stoichiometry of Cl-/HCO3- exchange by slc26a3 and slc26a6., Shcheynikov N,Wang Y,Park M,Ko SB,Dorwart M,Naruse S,Thomas PJ,Muallem S, J Gen Physiol. May 1, 2006; 127(5):1540-7748.

Functional and clinical characterization of a mutation in KCNJ2 associated with Andersen-Tawil syndrome., Lu CW,Lin JH,Rajawat YS,Jerng H,Rami TG,Sanchez X,DeFreitas G,Carabello B,DeMayo F,Kearney DL,Miller G,Li H,Pfaffinger PJ,Bowles NE,Khoury DS,Towbin JA, J Med Genet. August 1, 2006; 43(8):1468-6244.

The MRH protein Erlectin is a member of the endoplasmic reticulum synexpression group and functions in N-glycan recognition., Cruciat CM,Hassler C,Niehrs C, J Biol Chem. May 5, 2006; 281(18):1083-351X.

Emilin1 links TGF-beta maturation to blood pressure homeostasis., Zacchigna L,Vecchione C,Notte A,Cordenonsi M,Dupont S,Maretto S,Cifelli G,Ferrari A,Maffei A,Fabbro C,Braghetta P,Marino G,Selvetella G,Aretini A,Colonnese C,Bettarini U,Russo G,Soligo S,Adorno M,Bonaldo P,Volpin D,Piccolo S,Lembo G,Bressan GM, Cell. March 10, 2006; 124(5):1097-4172.

WNK3 bypasses the tonicity requirement for K-Cl cotransporter activation via a phosphatase-dependent pathway., de Los Heros P,Kahle KT,Rinehart J,Bobadilla NA,Vázquez N,San Cristobal P,Mount DB,Lifton RP,Hebert SC,Gamba G, Proc Natl Acad Sci U S A. February 7, 2006; 103(6):1091-6490.

Dystroglycan is required for proper retinal layering., Lunardi A,Cremisi F,Dente L, Dev Biol. February 15, 2006; 290(2):1095-564X.

A novel GJA8 mutation is associated with autosomal dominant lamellar pulverulent cataract: further evidence for gap junction dysfunction in human cataract., Arora A,Minogue PJ,Liu X,Reddy MA,Ainsworth JR,Bhattacharya SS,Webster AR,Hunt DM,Ebihara L,Moore AT,Beyer EC,Berthoud VM, J Med Genet. January 1, 2006; 43(1):1468-6244.

A dominant-negative form of the E3 ubiquitin ligase Cullin-1 disrupts the correct allocation of cell fate in the neural crest lineage., Voigt J,Papalopulu N, Development. February 1, 2006; 133(3):1477-9129.

Fanconi anemia proteins are required to prevent accumulation of replication-associated DNA double-strand breaks., Sobeck A,Stone S,Costanzo V,de Graaf B,Reuter T,de Winter J,Wallisch M,Akkari Y,Olson S,Wang W,Joenje H,Christian JL,Lupardus PJ,Cimprich KA,Gautier J,Hoatlin ME, Mol Cell Biol. January 1, 2006; 26(2):1098-5549.

Barrier-to-autointegration factor phosphorylation on Ser-4 regulates emerin binding to lamin A in vitro and emerin localization in vivo., Bengtsson L,Wilson KL, Mol Biol Cell. March 1, 2006; 17(3):1939-4586.

Dominant-negative effects of human P/Q-type Ca2+ channel mutations associated with episodic ataxia type 2., Jeng CJ,Chen YT,Chen YT,Chen YW,Chen YW,Tang CY, Am J Physiol Cell Physiol. April 1, 2006; 290(4):1522-1563.

A truncated Kv1.1 protein in the brain of the megencephaly mouse: expression and interaction., Persson AS,Klement G,Almgren M,Sahlholm K,Nilsson J,Petersson S,Arhem P,Schalling M,Lavebratt C, BMC Neurosci. November 23, 2005; 6:1471-2202.

The organization and inheritance of the mitochondrial genome., Chen XJ,Butow RA, Nat Rev Genet. November 1, 2005; 6(11):1471-0056.

WNK3 modulates transport of Cl- in and out of cells: implications for control of cell volume and neuronal excitability., Kahle KT,Rinehart J,de Los Heros P,Louvi A,Meade P,Vazquez N,Hebert SC,Gamba G,Gimenez I,Lifton RP, Proc Natl Acad Sci U S A. November 15, 2005; 102(46):1091-6490.

Xnf7 contributes to spindle integrity through its microtubule-bundling activity., Maresca TJ,Niederstrasser H,Weis K,Heald R, Curr Biol. October 11, 2005; 15(19):0960-9822.

Reduced U snRNP assembly causes motor axon degeneration in an animal model for spinal muscular atrophy., Winkler C,Eggert C,Gradl D,Meister G,Giegerich M,Wedlich D,Laggerbauer B,Fischer U, Genes Dev. October 1, 2005; 19(19):1549-5477.

Neural and eye-specific defects associated with loss of the imitation switch (ISWI) chromatin remodeler in Xenopus laevis., Dirscherl SS,Henry JJ,Krebs JE, Mech Dev. November 1, 2005; 122(11):1872-6356.

Cloning and functional characterization of the Xenopus orthologue of the Treacher Collins syndrome (TCOF1) gene product., Gonzales B,Yang H,Henning D,Valdez BC, Gene. October 10, 2005; 359:1879-0038.

ABCA4 mutations causing mislocalization are found frequently in patients with severe retinal dystrophies., Wiszniewski W,Zaremba CM,Yatsenko AN,Jamrich M,Wensel TG,Lewis RA,Lupski JR, Hum Mol Genet. October 1, 2005; 14(19):1460-2083.

A novel TMPRSS3 missense mutation in a DFNB8/10 family prevents proteolytic activation of the protein., Wattenhofer M,Sahin-Calapoglu N,Andreasen D,Kalay E,Caylan R,Braillard B,Fowler-Jaeger N,Reymond A,Rossier BC,Karaguzel A,Antonarakis SE, Hum Genet. October 1, 2005; 117(6):1432-1203.

Initiation of DNA replication requires the RECQL4 protein mutated in Rothmund-Thomson syndrome., Sangrithi MN,Bernal JA,Madine M,Philpott A,Lee J,Lee J,Dunphy WG,Venkitaraman AR, Cell. June 17, 2005; 121(6):1097-4172.

AP-2alpha selectively regulates fragile X mental retardation-1 gene transcription during embryonic development., Lim JH,Booker AB,Luo T,Williams T,Furuta Y,Lagutin O,Oliver G,Sargent TD,Fallon JR, Hum Mol Genet. July 15, 2005; 14(14):1460-2083.

Functional evaluation of Dent's disease-causing mutations: implications for ClC-5 channel trafficking and internalization., Ludwig M,Doroszewicz J,Seyberth HW,Bökenkamp A,Balluch B,Nuutinen M,Utsch B,Waldegger S, Hum Genet. July 1, 2005; 117(2-3):1432-1203.

WNK kinases and the control of blood pressure., Cope G,Golbang A,O'Shaughnessy KM, Pharmacol Ther. May 1, 2005; 106(2):0163-7258.

Mutation of single murine acetylcholine receptor subunits reveals differential contribution of P121 to acetylcholine binding and channel opening., Peter C,Korngreen A,Witzemann V, Pflugers Arch. June 1, 2005; 450(3):1432-2013.

A gating mutation at the internal mouth of the Kir6.2 pore is associated with DEND syndrome., Proks P,Girard C,Haider S,Gloyn AL,Hattersley AT,Sansom MS,Ashcroft FM, EMBO Rep. May 1, 2005; 6(5):1469-3178.

Severe arrhythmia disorder caused by cardiac L-type calcium channel mutations., Splawski I,Timothy KW,Decher N,Kumar P,Sachse FB,Beggs AH,Sanguinetti MC,Keating MT, Proc Natl Acad Sci U S A. June 7, 2005; 102(23):1091-6490.

Mechanism of proliferation arrest of embryonic cells of Xenopus by diterpene compounds., Okouchi T,Abe T,Araki S,Arai S,Iida T,Wang LY,Kitanaka S,Miyata S, Bioorg Med Chem. June 1, 2005; 13(11):1464-3391.

A novel positive allosteric modulator of the alpha7 neuronal nicotinic acetylcholine receptor: in vitro and in vivo characterization., Hurst RS,Hajós M,Raggenbass M,Wall TM,Higdon NR,Lawson JA,Rutherford-Root KL,Berkenpas MB,Hoffmann WE,Piotrowski DW,Groppi VE,Allaman G,Ogier R,Bertrand S,Bertrand D,Arneric SP, J Neurosci. April 27, 2005; 25(17):1529-2401.

Application of polyacrylamide gel electrophoresis of fluorophore-labeled saccharides for analysis of hyaluronan and chondroitin sulfate in human and animal tissues and cell cultures., Karousou EG,Viola M,Genasetti A,Vigetti D,Luca GD,Karamanos NK,Passi A, Biomed Chromatogr. December 1, 2005; 19(10):0269-3879.

Severe neuropathy with leaky connexin32 hemichannels., Liang GS,de Miguel M,Gómez-Hernández JM,Glass JD,Scherer SS,Mintz M,Barrio LC,Fischbeck KH, Ann Neurol. May 1, 2005; 57(5):1531-8249.

Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways., Simons M,Gloy J,Ganner A,Bullerkotte A,Bashkurov M,Krönig C,Schermer B,Benzing T,Cabello OA,Jenny A,Mlodzik M,Polok B,Driever W,Obara T,Walz G, Nat Genet. May 1, 2005; 37(5):1546-1718.

Polymorphic ventricular tachycardia and KCNJ2 mutations., Chun TU,Epstein MR,Dick M,Andelfinger G,Ballester L,Vanoye CG,George AL,Benson DW, Heart Rhythm. July 1, 2004; 1(2):1547-5271.

Kinetic properties of nuclear transport conferred by the retinoblastoma (Rb) NLS., Hu W,Kemp BE,Jans DA, J Cell Biochem. July 1, 2005; 95(4):0730-2312.

Simple sequence in brain and nervous system specific proteins., Huntley MA,Mahmood S,Golding GB, Genome. April 1, 2005; 48(2):0831-2796.

AGR2, an androgen-inducible secretory protein overexpressed in prostate cancer., Zhang JS,Gong A,Cheville JC,Smith DI,Young CY, Genes Chromosomes Cancer. July 1, 2005; 43(3):1045-2257.

Effect of galantamine on the human alpha7 neuronal nicotinic acetylcholine receptor, the Torpedo nicotinic acetylcholine receptor and spontaneous cholinergic synaptic activity., Texidó L,Ros E,Martín-Satué M,López S,Aleu J,Marsal J,Solsona C, Br J Pharmacol. July 1, 2005; 145(5):1476-5381.

Epithelial-connective tissue cross-talk is essential for regeneration of intestinal epithelium., Ishizuya-Oka A, J Nippon Med Sch. February 1, 2005; 72(1):1345-4676.

Induction of ectopic olfactory structures and bone morphogenetic protein inhibition by Rossy, a group XII secreted phospholipase A2., Muñoz-Sanjuán I,Brivanlou AH, Mol Cell Biol. May 1, 2005; 25(9):1098-5549.

ZW10 links mitotic checkpoint signaling to the structural kinetochore., Kops GJ,Kim Y,Weaver BA,Mao Y,McLeod I,Yates JR,Tagaya M,Cleveland DW, J Cell Biol. April 11, 2005; 169(1):1540-8140.

The influence of extracellular acidosis on the effect of IKr blockers., Lin C,Ke X,Cvetanovic I,Ranade V,Somberg J, J Cardiovasc Pharmacol Ther. March 1, 2005; 10(1):1074-2484.

Atrial natriuretic peptide inhibits the actions of FSH and forskolin in meiotic maturation of pig oocytes via different signalling pathways., Zhang M,Tao Y,Zhou B,Xie H,Wang F,Lei L,Huo L,Sun Q,Xia G, J Mol Endocrinol. April 1, 2005; 34(2):1479-6813.

Emerin expression in early development of Xenopus laevis., Gareiss M,Eberhardt K,Krüger E,Kandert S,Böhm C,Zentgraf H,Müller CR,Dabauvalle MC, Eur J Cell Biol. March 1, 2005; 84(2-3):0171-9335.

Polyspecific cation transporters mediate luminal release of acetylcholine from bronchial epithelium., Lips KS,Volk C,Schmitt BM,Pfeil U,Arndt P,Miska D,Ermert L,Kummer W,Koepsell H, Am J Respir Cell Mol Biol. July 1, 2005; 33(1):1535-4989.

Anxiolytic effects of Maxipost (BMS-204352) and retigabine via activation of neuronal Kv7 channels., Korsgaard MP,Hartz BP,Brown WD,Ahring PK,Strøbaek D,Mirza NR, J Pharmacol Exp Ther. July 1, 2005; 314(1):1521-0103.

Maternal wnt11 activates the canonical wnt signaling pathway required for axis formation in Xenopus embryos., Tao Q,Tao Q,Yokota C,Puck H,Kofron M,Birsoy B,Yan D,Asashima M,Wylie CC,Lin X,Heasman J, Cell. March 25, 2005; 120(6):1097-4172.

Functional polymorphisms in the human beta4 subunit of nicotinic acetylcholine receptors., Liang Y,Salas R,Marubio L,Bercovich D,De Biasi M,Beaudet AL,Dani JA, Neurogenetics. February 1, 2005; 6(1):1364-6745.

XTbx1 is a transcriptional activator involved in head and pharyngeal arch development in Xenopus laevis., Ataliotis P,Ivins S,Mohun TJ,Scambler PJ, Dev Dyn. April 1, 2005; 232(4):1058-8388.

Possible involvement of organic anion transporter 2 on the interaction of theophylline with erythromycin in the human liver., Kobayashi Y,Sakai R,Ohshiro N,Ohbayashi M,Kohyama N,Yamamoto T, Drug Metab Dispos. May 1, 2005; 33(5):1521-009X.

Ethanol exposure affects gene expression in the embryonic organizer and reduces retinoic acid levels., Yelin R,Schyr RB,Kot H,Zins S,Frumkin A,Pillemer G,Fainsod A, Dev Biol. March 1, 2005; 279(1):1095-564X.

In vitro functional analysis of human ferroportin (FPN) and hemochromatosis-associated FPN mutations., Schimanski LM,Drakesmith H,Merryweather-Clarke AT,Viprakasit V,Edwards JP,Sweetland E,Bastin JM,Cowley D,Chinthammitr Y,Robson KJ,Townsend AR, Blood. May 15, 2005; 105(10):1528-0020.

Rett syndrome: clinical review and genetic update., Weaving LS,Ellaway CJ,Gécz J,Christodoulou J, J Med Genet. January 1, 2005; 42(1):1468-6244.

Transgenic animal models of tauopathies., Lee VM,Kenyon TK,Trojanowski JQ, Biochim Biophys Acta. January 3, 2005; 1739(2-3):0006-3002.

The MinK-related peptides., McCrossan ZA,Abbott GW, Neuropharmacology. November 1, 2004; 47(6):1873-7064.

A structural basis for the acute effects of HIV protease inhibitors on GLUT4 intrinsic activity., Hertel J,Struthers H,Horj CB,Hruz PW, J Biol Chem. December 31, 2004; 279(53):1083-351X.

A novel missense mutation in the sodium bicarbonate cotransporter (NBCe1/SLC4A4) causes proximal tubular acidosis and glaucoma through ion transport defects., Dinour D,Chang MH,Satoh J,Smith BL,Smith BL,Angle N,Knecht A,Serban I,Holtzman EJ,Romero MF, J Biol Chem. December 10, 2004; 279(50):1083-351X.

The amino acid transporter asc-1 is not involved in cystinuria., Pineda M,Font M,Bassi MT,Manzoni M,Borsani G,Marigo V,Fernández E,Río RM,Purroy J,Zorzano A,Nunes V,Palacín M, Kidney Int. October 1, 2004; 66(4):1523-1755.

Ca(V)1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism., Splawski I,Timothy KW,Sharpe LM,Decher N,Kumar P,Bloise R,Napolitano C,Schwartz PJ,Joseph RM,Condouris K,Tager-Flusberg H,Priori SG,Sanguinetti MC,Keating MT, Cell. October 1, 2004; 119(1):1097-4172.

Familial hemiplegic migraine type 1 mutations K1336E, W1684R, and V1696I alter Cav2.1 Ca2+ channel gating: evidence for beta-subunit isoform-specific effects., Müllner C,Broos LA,van den Maagdenberg AM,Striessnig J, J Biol Chem. December 10, 2004; 279(50):1083-351X.

Regulation and function of small heat shock protein genes during amphibian development., Heikkila JJ, J Cell Biochem. November 1, 2004; 93(4):0730-2312.

Differential inhibition of nicotine- and acetylcholine-evoked currents through alpha4beta2 neuronal nicotinic receptors by tobacco cembranoids in Xenopus oocytes., Eaton MJ,Ospina CA,Rodríguez AD,Eterovi VA, Neurosci Lett. August 5, 2004; 366(1):1872-7972.

The Fanconi anemia gene product FANCF is a flexible adaptor protein., Léveillé F,Blom E,Medhurst AL,Bier P,Laghmani el H,Johnson M,Rooimans MA,Sobeck A,Waisfisz Q,Arwert F,Patel KJ,Hoatlin ME,Joenje H,de Winter JP, J Biol Chem. September 17, 2004; 279(38):1083-351X.

Evidence for stabilization of aquaporin-2 folding mutants by N-linked glycosylation in endoplasmic reticulum., Buck TM,Eledge J,Skach WR, Am J Physiol Cell Physiol. November 1, 2004; 287(5):1522-1563.

Uncoupling of photoreceptor peripherin/rds fusogenic activity from biosynthesis, subunit assembly, and targeting: a potential mechanism for pathogenic effects., Ritter LM,Boesze-Battaglia K,Tam BM,Moritz OL,Khattree N,Chen SC,Goldberg AF, J Biol Chem. September 17, 2004; 279(38):1083-351X.

Altered gating properties of functional Cx26 mutants associated with recessive non-syndromic hearing loss., Meşe G,Londin E,Mui R,Brink PR,White TW, Hum Genet. August 1, 2004; 115(3):1432-1203.

Analysis of missense variation in human BRCA1 in the context of interspecific sequence variation., Abkevich V,Zharkikh A,Deffenbaugh AM,Frank D,Chen Y,Chen Y,Shattuck D,Skolnick MH,Gutin A,Tavtigian SV, J Med Genet. July 1, 2004; 41(7):1468-6244.

A critical role of Pax6 in alcohol-induced fetal microcephaly., Peng Y,Yang PH,Ng SS,Wong OG,Liu J,He ML,Kung HF,Lin MC, Neurobiol Dis. July 1, 2004; 16(2):1095-953X.

Characterization of embryonic cardiac pacemaker and atrioventricular conduction physiology in Xenopus laevis using noninvasive imaging., Bartlett HL,Scholz TD,Lamb FS,Weeks DL, Am J Physiol Heart Circ Physiol. June 1, 2004; 286(6):0363-6135.

Mouse Zic5 deficiency results in neural tube defects and hypoplasia of cephalic neural crest derivatives., Inoue T,Hatayama M,Tohmonda T,Itohara S,Aruga J,Mikoshiba K, Dev Biol. June 1, 2004; 270(1):1095-564X.

Reverse transcriptase-based DNA vaccines against drug-resistant HIV-1 tested in a mouse model., Isaguliants MG,Zuber B,Boberg A,Sjöstrand D,Belikov SV,Rollman E,Zuber AK,Rechinsky VO,Rytting AS,Källander CF,Hinkula J,Kochetkov SN,Liu M,Wahren B, Vaccine. April 16, 2004; 22(13-14):0264-410X.

Cystic fibrosis transmembrane conductance regulator differentially regulates human and mouse epithelial sodium channels in Xenopus oocytes., Yan W,Samaha FF,Ramkumar M,Kleyman TR,Rubenstein RC, J Biol Chem. May 28, 2004; 279(22):1083-351X.

Modification of Kv2.1 K+ currents by the silent Kv10 subunits., Vega-Saenz de Miera EC, Brain Res Mol Brain Res. April 7, 2004; 123(1-2):0169-328X.

Identification of a novel gene, FGFR1OP2, fused to FGFR1 in 8p11 myeloproliferative syndrome., Grand EK,Grand FH,Chase AJ,Ross FM,Corcoran MM,Oscier DG,Cross NC, Genes Chromosomes Cancer. May 1, 2004; 40(1):1045-2257.

Aberrant gating, but a normal expression pattern, underlies the recessive phenotype of the deafness mutant Connexin26M34T., Skerrett IM,Di WL,Kasperek EM,Kelsell DP,Nicholson BJ, FASEB J. May 1, 2004; 18(7):1530-6860.

Modulation of DMT1 activity by redox compounds., Marciani P,Trotti D,Hediger MA,Monticelli G, J Membr Biol. January 15, 2004; 197(2):1432-1424.

Disruption of TRPM6/TRPM7 complex formation by a mutation in the TRPM6 gene causes hypomagnesemia with secondary hypocalcemia., Chubanov V,Waldegger S,Mederos y Schnitzler M,Vitzthum H,Sassen MC,Seyberth HW,Konrad M,Gudermann T, Proc Natl Acad Sci U S A. March 2, 2004; 101(9):1091-6490.

WNK4 regulates apical and basolateral Cl- flux in extrarenal epithelia., Kahle KT,Gimenez I,Hassan H,Wilson FH,Wong RD,Forbush B,Aronson PS,Lifton RP, Proc Natl Acad Sci U S A. February 17, 2004; 101(7):1091-6490.

A single nucleotide polymorphism alters the activity of the renal Na+:Cl- cotransporter and reveals a role for transmembrane segment 4 in chloride and thiazide affinity., Moreno E,Tovar-Palacio C,de los Heros P,Guzmán B,Bobadilla NA,Vázquez N,Riccardi D,Poch E,Gamba G, J Biol Chem. April 16, 2004; 279(16):1083-351X.

Microtransplantation of functional receptors and channels from the Alzheimer's brain to frog oocytes., Miledi R,Dueñas Z,Martinez-Torres A,Kawas CH,Eusebi F, Proc Natl Acad Sci U S A. February 10, 2004; 101(6):1091-6490.

A novel missense mutation in AE1 causing autosomal dominant distal renal tubular acidosis retains normal transport function but is mistargeted in polarized epithelial cells., Rungroj N,Devonald MA,Cuthbert AW,Reimann F,Akkarapatumwong V,Yenchitsomanus PT,Bennett WM,Karet FE, J Biol Chem. April 2, 2004; 279(14):1083-351X.

Catalase and peroxiredoxin 5 protect Xenopus embryos against alcohol-induced ocular anomalies., Peng Y,Yang PH,Guo Y,Ng SS,Liu J,Fung PC,Tay D,Ge J,He ML,Kung HF,Lin MC, Invest Ophthalmol Vis Sci. January 1, 2004; 45(1):1552-5783.

Functional characterization of two naturally occurring mutations in the human sodium-phosphate cotransporter type IIa., Virkki LV,Forster IC,Hernando N,Biber J,Murer H, J Bone Miner Res. December 1, 2003; 18(12):0884-0431.

Reversed polarized delivery of an aquaporin-2 mutant causes dominant nephrogenic diabetes insipidus., Kamsteeg EJ,Bichet DG,Konings IB,Nivet H,Lonergan M,Arthus MF,van Os CH,Deen PM, J Cell Biol. December 8, 2003; 163(5):1540-8140.

Bisphenol A induces feminization in Xenopus laevis tadpoles., Levy G,Lutz I,Krüger A,Kloas W, Environ Res. January 1, 2004; 94(1):0013-9351.

Pathogenesis of X-linked Charcot-Marie-Tooth disease: differential effects of two mutations in connexin 32., Abrams CK,Freidin M,Bukauskas F,Dobrenis K,Bargiello TA,Verselis VK,Bennett MV,Chen L,Sahenk Z, J Neurosci. November 19, 2003; 23(33):1529-2401.

A model of tripeptidyl-peptidase I (CLN2), a ubiquitous and highly conserved member of the sedolisin family of serine-carboxyl peptidases., Wlodawer A,Durell SR,Li M,Oyama H,Oda K,Dunn BM, BMC Struct Biol. November 11, 2003; 3:1472-6807.

Mutations linked to generalized epilepsy in humans reduce GABA(A) receptor current., Macdonald RL,Bianchi MT,Bianch MT,Feng H, Exp Neurol. November 1, 2003; 184 Suppl 1:0014-4886.

Loss-of-function mutations in the human GLI2 gene are associated with pituitary anomalies and holoprosencephaly-like features., Roessler E,Du YZ,Mullor JL,Casas E,Allen WP,Gillessen-Kaesbach G,Roeder ER,Ming JE,Ruiz i Altaba A,Muenke M, Proc Natl Acad Sci U S A. November 11, 2003; 100(23):1091-6490.

A mutant form of MeCP2 protein associated with human Rett syndrome cannot be displaced from methylated DNA by notch in Xenopus embryos., Stancheva I,Collins AL,Van den Veyver IB,Zoghbi H,Meehan RR, Mol Cell. August 1, 2003; 12(2):1097-4164.

Single-channel SCAM identifies pore-lining residues in the first extracellular loop and first transmembrane domains of Cx46 hemichannels., Kronengold J,Trexler EB,Bukauskas FF,Bargiello TA,Verselis VK, J Gen Physiol. October 1, 2003; 122(4):1540-7748.

Transcriptional and translational regulation of the Leri-Weill and Turner syndrome homeobox gene SHOX., Blaschke RJ,Töpfer C,Marchini A,Steinbeisser H,Janssen JW,Rappold GA, J Biol Chem. November 28, 2003; 278(48):1083-351X.

Zebrafish Cx35: cloning and characterization of a gap junction gene highly expressed in the retina., McLachlan E,White TW,Ugonabo C,Olson C,Nagy JI,Valdimarsson G, J Neurosci Res. September 15, 2003; 73(6):1097-4547.

Molecular motions of the outer ring of charge of the sodium channel: do they couple to slow inactivation?, Xiong W,Li RA,Tian Y,Tomaselli GF, J Gen Physiol. September 1, 2003; 122(3):1540-7748.

The role of ZIC3 in vertebrate development., Herman GE,El-Hodiri HM, Cytogenet Genome Res. January 1, 2002; 99(1-4):1424-859X.

Validation of the hexose transporter of Plasmodium falciparum as a novel drug target., Joet T,Eckstein-Ludwig U,Morin C,Krishna S, Proc Natl Acad Sci U S A. June 24, 2003; 100(13):1091-6490.

Opsin activation as a cause of congenital night blindness., Jin S,Cornwall MC,Oprian DD, Nat Neurosci. July 1, 2003; 6(7):1546-1726.

Functional characterization of a glutamate/aspartate transporter from the mosquito Aedes aegypti., Umesh A,Cohen BN,Ross LS,Gill SS, J Exp Biol. July 1, 2003; 206(Pt 13):1477-9145.

Down-regulation of GABA-transporter function by hippocampal translation products: its possible role in epilepsy., Fueta Y,Vasilets LA,Takeda K,Kawamura M,Schwarz W, Neuroscience. January 1, 2003; 118(2):1873-7544.

Effects of Chinese domestic polychlorinated biphenyls (PCBs) on gonadal differentiation in Xenopus laevis., Qin ZF,Zhou JM,Chu SG,Xu XB, Environ Health Perspect. April 1, 2003; 111(4):0091-6765.

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Species differences in Cl- affinity and in electrogenicity of SLC26A6-mediated oxalate/Cl- exchange correlate with the distinct human and mouse susceptibilities to nephrolithiasis., Clark JS,Vandorpe DH,Chernova MN,Heneghan JF,Stewart AK,Alper SL, J Physiol. March 1, 2008; 586(5):0022-3751.

A novel protein kinase signaling pathway essential for blood pressure regulation in humans., Kahle KT,Rinehart J,Giebisch G,Gamba G,Hebert SC,Lifton RP, Trends Endocrinol Metab. April 1, 2008; 19(3):1043-2760.

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Loss of nephrocystin-3 function can cause embryonic lethality, Meckel-Gruber-like syndrome, situs inversus, and renal-hepatic-pancreatic dysplasia., Bergmann C,Fliegauf M,Brüchle NO,Frank V,Olbrich H,Kirschner J,Schermer B,Schmedding I,Kispert A,Kränzlin B,Nürnberg G,Becker C,Grimm T,Girschick G,Lynch SA,Kelehan P,Senderek J,Neuhaus TJ,Stallmach T,Zentgraf H,Nürnberg P,Gretz N,Lo C,Lienkamp S,Schäfer T,Walz G,Benzing T,Zerres K,Omran H, Am J Hum Genet. April 1, 2008; 82(4):1537-6605.

Effect of atrazine on metamorphosis and sexual differentiation in Xenopus laevis., Oka T,Tooi O,Mitsui N,Miyahara M,Ohnishi Y,Takase M,Kashiwagi A,Shinkai T,Santo N,Iguchi T, Aquat Toxicol. May 30, 2008; 87(4):1879-1514.

Transcription factor HNF1beta and novel partners affect nephrogenesis., Dudziak K,Mottalebi N,Senkel S,Edghill EL,Rosengarten S,Roose M,Bingham C,Ellard S,Ryffel GU, Kidney Int. July 1, 2008; 74(2):1523-1755.

Arsenic as an endocrine disruptor: arsenic disrupts retinoic acid receptor-and thyroid hormone receptor-mediated gene regulation and thyroid hormone-mediated amphibian tail metamorphosis., Davey JC,Nomikos AP,Wungjiranirun M,Sherman JR,Ingram L,Batki C,Lariviere JP,Hamilton JW, Environ Health Perspect. February 1, 2008; 116(2):0091-6765.

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Organization of the pronephric kidney revealed by large-scale gene expression mapping., Raciti D,Reggiani L,Geffers L,Jiang Q,Bacchion F,Subrizi AE,Clements D,Tindal C,Davidson DR,Kaissling B,Brändli AW, Genome Biol. January 1, 2008; 9(5):1474-760X.

Use of tc-99m mebrofenin as a clinical probe to assess altered hepatobiliary transport: integration of in vitro, pharmacokinetic modeling, and simulation studies., Ghibellini G,Leslie EM,Pollack GM,Brouwer KL, Pharm Res. August 1, 2008; 25(8):1573-904X.

Small molecule activator of the human epithelial sodium channel., Lu M,Echeverri F,Kalabat D,Laita B,Dahan DS,Smith RD,Xu H,Staszewski L,Yamamoto J,Ling J,Hwang N,Kimmich R,Li P,Patron E,Keung W,Patron A,Moyer BD, J Biol Chem. May 2, 2008; 283(18):1083-351X.

Functional and structural characterization of PKA-mediated pHi gating of ROMK1 channels., Lee CH,Lee CH,Lee CH,Huang PT,Lou KL,Liou HH, J Mol Graph Model. October 1, 2008; 27(3):1873-4243.

Microtransplantation of neurotransmitter receptors from postmortem autistic brains to Xenopus oocytes., Limon A,Reyes-Ruiz JM,Miledi R, Proc Natl Acad Sci U S A. August 5, 2008; 105(31):1091-6490.

Three matrix metalloproteinases are required in vivo for macrophage migration during embryonic development., Tomlinson ML,Garcia-Morales C,Abu-Elmagd M,Wheeler GN, Mech Dev. January 1, 2008; 125(11-12):1872-6356.

Genetic and physical interaction between the NPHP5 and NPHP6 gene products., Schäfer T,Pütz M,Lienkamp S,Ganner A,Bergbreiter A,Ramachandran H,Gieloff V,Gerner M,Mattonet C,Czarnecki PG,Sayer JA,Otto EA,Hildebrandt F,Kramer-Zucker A,Walz G, Hum Mol Genet. December 1, 2008; 17(23):1460-2083.

Promoting ectopic pancreatic fates: pancreas development and future diabetes therapies., Pearl EJ,Horb ME, Clin Genet. October 1, 2008; 74(4):1399-0004.

Expression cloning of TMEM16A as a calcium-activated chloride channel subunit., Schroeder BC,Cheng T,Jan YN,Jan LY, Cell. September 19, 2008; 134(6):1097-4172.

Secreted Frizzled-related protein 2 is a procollagen C proteinase enhancer with a role in fibrosis associated with myocardial infarction., Kobayashi K,Luo M,Zhang Y,Zhang Y,Wilkes DC,Ge G,Grieskamp T,Yamada C,Liu TC,Huang G,Basson CT,Kispert A,Greenspan DS,Sato TN, Nat Cell Biol. January 1, 2009; 11(1):1476-4679.

A homozygous missense mutation in the IRBP gene (RBP3) associated with autosomal recessive retinitis pigmentosa., den Hollander AI,McGee TL,Ziviello C,Banfi S,Dryja TP,Gonzalez-Fernandez F,Ghosh D,Berson EL, Invest Ophthalmol Vis Sci. April 1, 2009; 50(4):1552-5783.

Does atrazine influence larval development and sexual differentiation in Xenopus laevis?, Kloas W,Lutz I,Springer T,Krueger H,Wolf J,Holden L,Hosmer A, Toxicol Sci. February 1, 2009; 107(2):1096-0929.

Novel, potent, and selective GABAC antagonists inhibit myopia development and facilitate learning and memory., Chebib M,Hinton T,Schmid KL,Brinkworth D,Qian H,Matos S,Kim HL,Abdel-Halim H,Kumar RJ,Johnston GA,Hanrahan JR, J Pharmacol Exp Ther. February 1, 2009; 328(2):1521-0103.

Single-channel analysis of functional epithelial sodium channel (ENaC) stability at the apical membrane of A6 distal kidney cells., Yu L,Helms MN,Yue Q,Eaton DC, Am J Physiol Renal Physiol. November 1, 2008; 295(5):1522-1466.

Novel treatment for lithium-induced nephrogenic diabetes insipidus rat model using the Sendai-virus vector carrying aquaporin 2 gene., Suga H,Nagasaki H,Kondo TA,Okajima Y,Suzuki C,Ozaki N,Arima H,Yamamoto T,Ozaki N,Akai M,Sato A,Uozumi N,Inoue M,Hasegawa M,Oiso Y, Endocrinology. November 1, 2008; 149(11):1945-7170.

Heme metabolism enzymes are dynamically expressed during Xenopus embryonic development., Shi J,Mei W,Yang J, Biocell. December 1, 2008; 32(3):0327-9545.

ING function in apoptosis in diverse model systems., Shah S,Smith H,Feng X,Rancourt DE,Riabowol K, Biochem Cell Biol. February 1, 2009; 87(1):1208-6002.

Biophysical properties of zebrafish ether-à-go-go related gene potassium channels., Scholz EP,Niemer N,Hassel D,Zitron E,Bürgers HF,Bloehs R,Seyler C,Scherer D,Thomas D,Kathöfer S,Katus HA,Rottbauer WA,Karle CA, Biochem Biophys Res Commun. April 3, 2009; 381(2):1090-2104.

The colorectal cancer risk at 18q21 is caused by a novel variant altering SMAD7 expression., Pittman AM,Naranjo S,Webb E,Broderick P,Lips EH,van Wezel T,Morreau H,Sullivan K,Fielding S,Twiss P,Vijayakrishnan J,Casares F,Qureshi M,Gómez-Skarmeta JL,Houlston RS, Genome Res. June 1, 2009; 19(6):1549-5469.

Discovery and characterization of a small molecule inhibitor of the PDZ domain of dishevelled., Grandy D,Shan J,Zhang X,Rao S,Akunuru S,Li H,Zhang Y,Zhang Y,Alpatov I,Zhang XA,Lang RA,Shi DL,Zheng JJ, J Biol Chem. June 12, 2009; 284(24):1083-351X.

Epilepsy, ataxia, sensorineural deafness, tubulopathy, and KCNJ10 mutations., Bockenhauer D,Feather S,Stanescu HC,Bandulik S,Zdebik AA,Reichold M,Tobin J,Lieberer E,Sterner C,Landoure G,Arora R,Sirimanna T,Thompson D,Cross JH,van't Hoff W,Al Masri O,Tullus K,Yeung S,Anikster Y,Klootwijk E,Hubank M,Dillon MJ,Heitzmann D,Arcos-Burgos M,Knepper MA,Dobbie A,Gahl WA,Warth R,Sheridan E,Kleta R, N Engl J Med. May 7, 2009; 360(19):1533-4406.

Influence of lamin A on the mechanical properties of amphibian oocyte nuclei measured by atomic force microscopy., Schäpe J,Prausse S,Radmacher M,Stick R, Biophys J. May 20, 2009; 96(10):1542-0086.

An in vivo chemical library screen in Xenopus tadpoles reveals novel pathways involved in angiogenesis and lymphangiogenesis., Kälin RE,Bänziger-Tobler NE,Detmar M,Brändli AW, Blood. July 30, 2009; 114(5):1528-0020.

Reduced levels of survival motor neuron protein leads to aberrant motoneuron growth in a Xenopus model of muscular atrophy., Ymlahi-Ouazzani Q,J Bronchain O,Paillard E,Ballagny C,Chesneau A,Jadaud A,Mazabraud A,Pollet N, Neurogenetics. February 1, 2010; 11(1):1364-6745.

Mutations of KCNJ10 together with mutations of SLC26A4 cause digenic nonsyndromic hearing loss associated with enlarged vestibular aqueduct syndrome., Yang T,Gurrola JG,Wu H,Chiu SM,Wangemann P,Snyder PM,Smith RJ, Am J Hum Genet. May 1, 2009; 84(5):1537-6605.

A surface transporter family conveys the trypanosome differentiation signal., Dean S,Marchetti R,Kirk K,Matthews KR, Nature. May 14, 2009; 459(7244):0143-5221.

Slc26a9 is inhibited by the R-region of the cystic fibrosis transmembrane conductance regulator via the STAS domain., Chang MH,Plata C,Sindic A,Ranatunga WK,Chen AP,Zandi-Nejad K,Chan KW,Thompson J,Mount DB,Romero MF, J Biol Chem. October 9, 2009; 284(41):1083-351X.

Alternative splicing of the Anopheles gambiae nicotinic acetylcholine receptor, Agamalphabeta9, generates both alpha and beta subunits., Jones AK,Buckingham SD,Brown LA,Sattelle DB, Invert Neurosci. November 1, 2009; 9(2):1439-1104.

Mutations in PYCR1 cause cutis laxa with progeroid features., Reversade B,Escande-Beillard N,Dimopoulou A,Fischer B,Chng SC,Li Y,Shboul M,Tham PY,Kayserili H,Al-Gazali L,Shahwan M,Brancati F,Lee H,Lee H,O'Connor BD,Schmidt-von Kegler M,Merriman B,Nelson SF,Masri A,Alkazaleh F,Guerra D,Ferrari P,Nanda A,Rajab A,Markie D,Gray M,Nelson J,Grix A,Sommer A,Savarirayan R,Janecke AR,Steichen E,Sillence D,Hausser I,Budde B,Nürnberg G,Nürnberg P,Seemann P,Kunkel D,Zambruno G,Dallapiccola B,Schuelke M,Robertson S,Hamamy H,Wollnik B,Van Maldergem L,Mundlos S,Kornak U, Nat Genet. September 1, 2009; 41(9):1546-1718.

Vestibular asymmetry as the cause of idiopathic scoliosis: a possible answer from Xenopus., Lambert FM,Malinvaud D,Glaunès J,Bergot C,Straka H,Vidal PP, J Neurosci. October 7, 2009; 29(40):1529-2401.

Lessons from the lily pad: Using Xenopus to understand heart disease., Bartlett HL,Weeks DL, Drug Discov Today Dis Models. January 1, 2008; 5(3):1740-6757.

A functional null mutation of SCN1B in a patient with Dravet syndrome., Patino GA,Claes LR,Lopez-Santiago LF,Slat EA,Dondeti RS,Chen C,O'Malley HA,Gray CB,Miyazaki H,Nukina N,Oyama F,De Jonghe P,Isom LL, J Neurosci. August 26, 2009; 29(34):1529-2401.

The hydrolethalus syndrome protein HYLS-1 links core centriole structure to cilia formation., Dammermann A,Pemble H,Mitchell BJ,McLeod I,Yates JR,Kintner C,Desai AB,Oegema K, Genes Dev. September 1, 2009; 23(17):1549-5477.

A recombinant N-terminal domain fully restores deactivation gating in N-truncated and long QT syndrome mutant hERG potassium channels., Gustina AS,Trudeau MC, Proc Natl Acad Sci U S A. August 4, 2009; 106(31):1091-6490.

Learning about cancer from frogs: analysis of mitotic spindles in Xenopus egg extracts., Cross MK,Powers MA, Dis Model Mech. January 1, 2009; 2(11-12):1754-8411.

The miR-30 miRNA family regulates Xenopus pronephros development and targets the transcription factor Xlim1/Lhx1., Agrawal R,Tran U,Wessely O, Development. December 1, 2009; 136(23):1477-9129.

EYA1 mutations associated with the branchio-oto-renal syndrome result in defective otic development in Xenopus laevis., Li Y,Manaligod JM,Weeks DL, Biol Cell. February 17, 2010; 102(5):1768-322X.

Monoketone analogs of curcumin, a new class of Fanconi anemia pathway inhibitors., Landais I,Hiddingh S,McCarroll M,Yang C,Sun A,Turker MS,Snyder JP,Hoatlin ME, Mol Cancer. December 31, 2009; 8:1476-4598.

The target of the NSD family of histone lysine methyltransferases depends on the nature of the substrate., Li Y,Trojer P,Xu CF,Cheung P,Kuo A,Drury WJ,Qiao Q,Neubert TA,Xu RM,Gozani O,Reinberg D, J Biol Chem. December 4, 2009; 284(49):1083-351X.

Neurodevelopmental effects of chronic exposure to elevated levels of pro-inflammatory cytokines in a developing visual system., Lee RH,Mills EA,Schwartz N,Bell MR,Deeg KE,Ruthazer ES,Marsh-Armstrong N,Aizenman CD, Neural Dev. January 4, 2010; 5:1749-8104.

A non-enzymatic function of 17beta-hydroxysteroid dehydrogenase type 10 is required for mitochondrial integrity and cell survival., Rauschenberger K,Schöler K,Sass JO,Sauer S,Djuric Z,Rumig C,Wolf NI,Okun JG,Kölker S,Schwarz H,Fischer C,Grziwa B,Runz H,Nümann A,Shafqat N,Kavanagh KL,Hämmerling G,Wanders RJ,Shield JP,Wendel U,Stern D,Nawroth P,Hoffmann GF,Bartram CR,Arnold B,Bierhaus A,Oppermann U,Steinbeisser H,Zschocke J, EMBO Mol Med. February 1, 2010; 2(2):1757-4684.

An alpha7 nicotinic acetylcholine receptor-selective agonist reduces weight gain and metabolic changes in a mouse model of diabetes., Marrero MB,Lucas R,Salet C,Hauser TA,Mazurov A,Lippiello PM,Bencherif M, J Pharmacol Exp Ther. January 1, 2010; 332(1):1521-0103.

CHD7 cooperates with PBAF to control multipotent neural crest formation., Bajpai R,Chen DA,Rada-Iglesias A,Zhang J,Xiong Y,Helms J,Chang CP,Zhao Y,Swigut T,Wysocka J, Nature. February 18, 2010; 463(7283):0143-5221.

GJB2 mutations in Mongolia: complex alleles, low frequency, and reduced fitness of the deaf., Tekin M,Xia XJ,Erdenetungalag R,Cengiz FB,White TW,Radnaabazar J,Dangaasuren B,Tastan H,Nance WE,Pandya A, Ann Hum Genet. March 1, 2010; 74(2):1469-1809.

Atrazine induces complete feminization and chemical castration in male African clawed frogs (Xenopus laevis)., Hayes TB,Khoury V,Narayan A,Nazir M,Park A,Brown T,Adame L,Chan E,Buchholz D,Stueve T,Gallipeau S, Proc Natl Acad Sci U S A. March 9, 2010; 107(10):1091-6490.

Regulated transport of sulfate and oxalate by SLC26A2/DTDST., Heneghan JF,Akhavein A,Salas MJ,Shmukler BE,Karniski LP,Vandorpe DH,Alper SL, Am J Physiol Cell Physiol. June 1, 2010; 298(6):1522-1563.

APCDD1 is a novel Wnt inhibitor mutated in hereditary hypotrichosis simplex., Shimomura Y,Agalliu D,Vonica A,Luria V,Wajid M,Baumer A,Belli S,Petukhova L,Schinzel A,Brivanlou AH,Brivanlou AH,Barres BA,Christiano AM, Nature. April 15, 2010; 464(7291):0143-5221.

Testing the effects of FSHD candidate gene expression in vertebrate muscle development., Wuebbles RD,Long SW,Hanel ML,Jones PL, Int J Clin Exp Pathol. March 28, 2010; 3(4):1936-2625.

The BMP pathway acts to directly regulate Tbx20 in the developing heart., Mandel EM,Kaltenbrun E,Callis TE,Zeng XX,Marques SR,Yelon D,Wang DZ,Conlon FL, Development. June 1, 2010; 137(11):1477-9129.

Basolateral Cl- uptake mechanisms in Xenopus laevis lung epithelium., Berger J,Hardt M,Clauss WG,Fronius M, Am J Physiol Regul Integr Comp Physiol. July 1, 2010; 299(1):1522-1490.

Enhancement of GABA(A)-current run-down in the hippocampus occurs at the first spontaneous seizure in a model of temporal lobe epilepsy., Mazzuferi M,Palma E,Martinello K,Maiolino F,Roseti C,Fucile S,Fabene PF,Schio F,Pellitteri M,Sperk G,Miledi R,Eusebi F,Simonato M, Proc Natl Acad Sci U S A. February 16, 2010; 107(7):1091-6490.

Wild-type and brachyolmia-causing mutant TRPV4 channels respond directly to stretch force., Loukin S,Zhou X,Zhou X,Su Z,Saimi Y,Kung C, J Biol Chem. August 27, 2010; 285(35):1083-351X.

Planar cell polarity acts through septins to control collective cell movement and ciliogenesis., Kim SK,Shindo A,Park TJ,Oh EC,Ghosh S,Gray RS,Lewis RA,Johnson CA,Attie-Bittach T,Katsanis N,Wallingford JB, Science. September 10, 2010; 329(5997):1095-9203.

An epilepsy/dyskinesia-associated mutation enhances BK channel activation by potentiating Ca2+ sensing., Yang J,Krishnamoorthy G,Saxena A,Zhang G,Shi J,Yang H,Delaloye K,Sept D,Cui J, Neuron. June 24, 2010; 66(6):0896-6273.

Antitumor and anti-angiogenesis immunity induced by CR-SEREX-identified Xenopus RHAMM., Yang HS,Zhang DM,Deng HX,Peng F,Wei YQ, Cancer Sci. April 1, 2010; 101(4):1349-7006.

Human sodium phosphate transporter 4 (hNPT4/SLC17A3) as a common renal secretory pathway for drugs and urate., Jutabha P,Anzai N,Kitamura K,Taniguchi A,Kaneko S,Yan K,Yamada H,Shimada H,Kimura T,Katada T,Fukutomi T,Tomita K,Urano W,Yamanaka H,Seki G,Fujita T,Moriyama Y,Yamada A,Uchida S,Wempe MF,Endou H,Sakurai H, J Biol Chem. November 5, 2010; 285(45):1083-351X.

A regulatory calcium-binding site at the subunit interface of CLC-K kidney chloride channels., Gradogna A,Babini E,Picollo A,Pusch M, J Gen Physiol. September 1, 2010; 136(3):1540-7748.

Proton block of the CLC-5 Cl-/H+ exchanger., Picollo A,Malvezzi M,Accardi A, J Gen Physiol. June 1, 2010; 135(6):1540-7748.

Polycystin-2 activity is controlled by transcriptional coactivator with PDZ binding motif and PALS1-associated tight junction protein., Duning K,Rosenbusch D,Schlüter MA,Tian Y,Kunzelmann K,Meyer N,Schulze U,Markoff A,Pavenstädt H,Weide T, J Biol Chem. October 29, 2010; 285(44):1083-351X.

Small molecule disruption of G beta gamma signaling inhibits the progression of heart failure., Casey LM,Pistner AR,Belmonte SL,Migdalovich D,Stolpnik O,Nwakanma FE,Vorobiof G,Dunaevsky O,Matavel A,Lopes CM,Smrcka AV,Blaxall BC, Circ Res. August 20, 2010; 107(4):1524-4571.

A sodium channel mutation identified in Aedes aegypti selectively reduces cockroach sodium channel sensitivity to type I, but not type II pyrethroids., Hu Z,Du Y,Nomura Y,Dong K, Insect Biochem Mol Biol. January 1, 2011; 41(1):1879-0240.

Shox2 mediates Tbx5 activity by regulating Bmp4 in the pacemaker region of the developing heart., Puskaric S,Schmitteckert S,Mori AD,Glaser A,Schneider KU,Bruneau BG,Blaschke RJ,Steinbeisser H,Rappold G, Hum Mol Genet. December 1, 2010; 19(23):1460-2083.

Neurological disease mutations compromise a C-terminal ion pathway in the Na(+)/K(+)-ATPase., Poulsen H,Khandelia H,Morth JP,Bublitz M,Mouritsen OG,Egebjerg J,Nissen P, Nature. September 2, 2010; 467(7311):0143-5221.

Small-molecule inhibition of Wnt signaling through activation of casein kinase 1α., Thorne CA,Hanson AJ,Schneider J,Tahinci E,Orton D,Cselenyi CS,Jernigan KK,Meyers KC,Hang BI,Waterson AG,Kim K,Melancon B,Ghidu VP,Sulikowski GA,LaFleur B,Salic A,Lee LA,Miller DM,Lee E,Lee E, Nat Chem Biol. November 1, 2010; 6(11):1552-4469.

Aberrant activation of fatty acid synthesis suppresses primary cilium formation and distorts tissue development., Willemarck N,Rysman E,Brusselmans K,Van Imschoot G,Vanderhoydonc F,Moerloose K,Lerut E,Verhoeven G,van Roy F,Vleminckx K,Vleminckx K,Swinnen JV, Cancer Res. November 15, 2010; 70(22):1538-7445.

Inversin relays Frizzled-8 signals to promote proximal pronephros development., Lienkamp S,Ganner A,Boehlke C,Schmidt T,Arnold SJ,Schäfer T,Romaker D,Schuler J,Hoff S,Powelske C,Eifler A,Krönig C,Bullerkotte A,Nitschke R,Kuehn EW,Kim E,Burkhardt H,Brox T,Ronneberger O,Gloy J,Walz G, Proc Natl Acad Sci U S A. November 23, 2010; 107(47):1091-6490.

Development of a novel selective inhibitor of the Down syndrome-related kinase Dyrk1A., Ogawa Y,Nonaka Y,Goto T,Ohnishi E,Hiramatsu T,Kii I,Yoshida M,Ikura T,Onogi H,Shibuya H,Hosoya T,Ito N,Hagiwara M, Nat Commun. October 5, 2010; 1:2041-1723.

Transmembrane potential of GlyCl-expressing instructor cells induces a neoplastic-like conversion of melanocytes via a serotonergic pathway., Blackiston D,Adams DS,Lemire JM,Lobikin M,Levin M, Dis Model Mech. January 1, 2011; 4(1):1754-8411.

NMDA-mediated regulation of DSCAM dendritic local translation is lost in a mouse model of Down's syndrome., Alves-Sampaio A,Troca-Marín JA,Montesinos ML, J Neurosci. October 6, 2010; 30(40):1529-2401.

Functional coupling between the extracellular matrix and nuclear lamina by Wnt signaling in progeria., Hernandez L,Roux KJ,Wong ES,Mounkes LC,Mutalif R,Navasankari R,Rai B,Cool S,Jeong JW,Wang H,Lee HS,Lee HS,Kozlov S,Grunert M,Keeble T,Jones CM,Meta MD,Young SG,Daar IO,Burke B,Perantoni AO,Stewart CL, Dev Cell. September 14, 2010; 19(3):1878-1551.

Paraxial T-box genes, Tbx6 and Tbx1, are required for cranial chondrogenesis and myogenesis., Tazumi S,Yabe S,Uchiyama H, Dev Biol. October 15, 2010; 346(2):1095-564X.

Multiple enhancers located in a 1-Mb region upstream of POU3F4 promote expression during inner ear development and may be required for hearing., Naranjo S,Voesenek K,de la Calle-Mustienes E,Robert-Moreno A,Kokotas H,Grigoriadou M,Economides J,Van Camp G,Hilgert N,Moreno F,Alsina B,Petersen MB,Kremer H,Gómez-Skarmeta JL, Hum Genet. October 1, 2010; 128(4):1432-1203.

Potential role of caveolin-1-positive domains in the regulation of the acetylcholine receptor's activatable pool: implications in the pathogenesis of a novel congenital myasthenic syndrome., Báez-Pagán CA,Martínez-Ortiz Y,Otero-Cruz JD,Salgado-Villanueva IK,Velázquez G,Ortiz-Acevedo A,Quesada O,Silva WI,Lasalde-Dominicci JA, Channels (Austin). January 1, 2008; 2(3):1933-6969.

Developmental expression patterns of candidate cofactors for vertebrate six family transcription factors., Neilson KM,Pignoni F,Yan B,Moody SA, Dev Dyn. December 1, 2010; 239(12):1058-8388.

Molecular basis of decreased Kir4.1 function in SeSAME/EAST syndrome., Williams DM,Lopes CM,Rosenhouse-Dantsker A,Connelly HL,Matavel A,O-Uchi J,McBeath E,Gray DA, J Am Soc Nephrol. December 1, 2010; 21(12):1533-3450.

Tamm-Horsfall glycoprotein interacts with renal outer medullary potassium channel ROMK2 and regulates its function., Renigunta A,Renigunta V,Saritas T,Decher N,Mutig K,Waldegger S, J Biol Chem. January 21, 2011; 286(3):1083-351X.

Animal models for autosomal dominant frontal lobe epilepsy: on the origin of seizures., Steinlein OK, Expert Rev Neurother. December 1, 2010; 10(12):1744-8360.

ATP induces conformational changes in the carboxyl-terminal region of ClC-5., Wellhauser L,Luna-Chavez C,D'Antonio C,Tainer J,Bear CE, J Biol Chem. February 25, 2011; 286(8):1083-351X.

An essential role of the cysteine-rich domain of FZD4 in Norrin/Wnt signaling and familial exudative vitreoretinopathy., Zhang K,Harada Y,Wei X,Shukla D,Rajendran A,Tawansy K,Bedell M,Lim S,Shaw PX,He X,Yang Z, J Biol Chem. March 25, 2011; 286(12):1083-351X.

Mitochondrial apoptosis-induced channel (MAC) function triggers a Bax/Bak-dependent bystander effect., Peixoto PM,Lue JK,Ryu SY,Wroble BN,Sible JC,Kinnally KW, Am J Pathol. January 1, 2011; 178(1):1525-2191.

Biophysical properties of mutant KCNQ1 S277L channels linked to hereditary long QT syndrome with phenotypic variability., Aidery P,Kisselbach J,Schweizer PA,Becker R,Katus HA,Thomas D, Biochim Biophys Acta. April 1, 2011; 1812(4):0006-3002.

A homozygous nonsense mutation (c.214C->A) in the biliverdin reductase alpha gene (BLVRA) results in accumulation of biliverdin during episodes of cholestasis., Nytofte NS,Serrano MA,Monte MJ,Gonzalez-Sanchez E,Tumer Z,Ladefoged K,Briz O,Marin JJ, J Med Genet. April 1, 2011; 48(4):1468-6244.

Specification of ion transport cells in the Xenopus larval skin., Quigley IK,Stubbs JL,Kintner C, Development. February 1, 2011; 138(4):1477-9129.

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The TM2 6' position of GABA(A) receptors mediates alcohol inhibition., Johnson WD,Howard RJ,Trudell JR,Harris RA, J Pharmacol Exp Ther. February 1, 2012; 340(2):1521-0103.

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Kcna1-mutant rats dominantly display myokymia, neuromyotonia and spontaneous epileptic seizures., Ishida S,Sakamoto Y,Nishio T,Baulac S,Kuwamura M,Ohno Y,Takizawa A,Kaneko S,Serikawa T,Mashimo T, Dev Biol. January 30, 2012; 1435:0012-1606.

An essential and highly conserved role for Zic3 in left-right patterning, gastrulation and convergent extension morphogenesis., Cast AE,Gao C,Amack JD,Ware SM, Dev Biol. April 1, 2012; 364(1):1095-564X.

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Mechanism of inhibition of connexin channels by the quinine derivative N-benzylquininium., Rubinos C,Sánchez HA,Verselis VK,Srinivas M, J Gen Physiol. January 1, 2012; 139(1):1540-7748.

Suppression of Bmp4 signaling by the zinc-finger repressors Osr1 and Osr2 is required for Wnt/β-catenin-mediated lung specification in Xenopus., Rankin SA,Rankin SA,Gallas AL,Neto A,Gómez-Skarmeta JL,Zorn AM, Development. August 1, 2012; 139(16):1477-9129.

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Live imaging of targeted cell ablation in Xenopus: a new model to study demyelination and repair., Kaya F,Mannioui A,Chesneau A,Sekizar S,Maillard E,Ballagny C,Houel-Renault L,Dupasquier D,Bronchain O,Holtzmann I,Desmazieres A,Thomas JL,Demeneix BA,Brophy PJ,Zalc B,Mazabraud A, J Neurosci. September 12, 2012; 32(37):1529-2401.

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Control of vertebrate intraflagellar transport by the planar cell polarity effector Fuz., Brooks ER,Wallingford JB, J Cell Biol. July 9, 2012; 198(1):1540-8140.

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Functional and structural effects of amyloid-β aggregate on Xenopus laevis oocytes., Parodi J,Ochoa-de la Paz L,Miledi R,Martínez-Torres A, Mol Cells. October 1, 2012; 34(4):0219-1032.

An MIP/AQP0 mutation with impaired trafficking and function underlies an autosomal dominant congenital lamellar cataract., Senthil Kumar G,Kyle JW,Minogue PJ,Dinesh Kumar K,Vasantha K,Berthoud VM,Beyer EC,Santhiya ST, Exp Eye Res. May 1, 2013; 110:0014-4835.

Embryonic exposure to propylthiouracil disrupts left-right patterning in Xenopus embryos., van Veenendaal NR,Ulmer B,Boskovski MT,Fang X,Khokha MK,Wendler CC,Blum M,Rivkees SA, FASEB J. February 1, 2013; 27(2):1530-6860.

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Exon capture and bulk segregant analysis: rapid discovery of causative mutations using high-throughput sequencing., del Viso F,Bhattacharya D,Kong Y,Gilchrist MJ,Khokha MK, BMC Genomics. November 21, 2012; 13:1471-2164.

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Functional analysis of nonsynonymous single nucleotide polymorphisms in human SLC26A9., Chen AP,Chang MH,Romero MF, Hum Mutat. August 1, 2012; 33(8):1098-1004.

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Imbalance of Hsp70 family variants fosters tau accumulation., Jinwal UK,Akoury E,Abisambra JF,O'Leary JC,Thompson AD,Blair LJ,Jin Y,Bacon J,Nordhues BA,Cockman M,Zhang J,Li P,Zhang B,Borysov S,Uversky VN,Biernat J,Mandelkow E,Gestwicki JE,Zweckstetter M,Dickey CA, FASEB J. April 1, 2013; 27(4):1530-6860.

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Functional analysis of missense mutations in Kv8.2 causing cone dystrophy with supernormal rod electroretinogram., Smith KE,Wilkie SE,Tebbs-Warner JT,Jarvis BJ,Gallasch L,Stocker M,Hunt DM, J Biol Chem. December 21, 2012; 287(52):1083-351X.

Transmembrane voltage potential is an essential cellular parameter for the detection and control of tumor development in a Xenopus model., Chernet BT,Levin M, Dis Model Mech. May 1, 2013; 6(3):1754-8411.

Restricted neural plasticity in vestibulospinal pathways after unilateral labyrinthectomy as the origin for scoliotic deformations., Lambert FM,Malinvaud D,Gratacap M,Straka H,Vidal PP, J Neurosci. April 17, 2013; 33(16):1529-2401.

Connexins in epidermal homeostasis and skin disease., Scott CA,Tattersall D,O'Toole EA,Kelsell DP, Biochim Biophys Acta. August 1, 2012; 1818(8):0006-3002.

Identification and characterization of a small-molecule inhibitor of Wnt signaling in glioblastoma cells., De Robertis A,Valensin S,Rossi M,Tunici P,Verani M,De Rosa A,Giordano C,Varrone M,Nencini A,Pratelli C,Benicchi T,Bakker A,Hill J,Sangthongpitag K,Pendharkar V,Liu B,Ng FM,Then SW,Jing Tai S,Cheong SM,He X,Caricasole A,Salerno M, Mol Cancer Ther. July 1, 2013; 12(7):1538-8514.

Towards a humanized PPARγ reporter system for in vivo screening of obesogens., Punzon I,Latapie V,Le Mével S,Hagneau A,Jolivet P,Palmier K,Fini JB,Demeneix BA, Mol Cell Endocrinol. July 15, 2013; 374(1-2):1872-8057.

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Gout-causing Q141K mutation in ABCG2 leads to instability of the nucleotide-binding domain and can be corrected with small molecules., Woodward OM,Tukaye DN,Cui J,Greenwell P,Constantoulakis LM,Parker BS,Rao A,Köttgen M,Maloney PC,Guggino WB, Proc Natl Acad Sci U S A. March 26, 2013; 110(13):1091-6490.

MCTP2 is a dosage-sensitive gene required for cardiac outflow tract development., Lalani SR,Ware SM,Wang X,Zapata G,Tian Q,Franco LM,Jiang Z,Jiang Z,Bucasas K,Scott DA,Campeau PM,Hanchard N,Umaña L,Cast A,Patel A,Cheung SW,McBride KL,Bray M,Craig Chinault A,Boggs BA,Huang M,Baker MR,Hamilton S,Towbin J,Jefferies JL,Fernbach SD,Potocki L,Belmont JW, Hum Mol Genet. November 1, 2013; 22(21):1460-2083.

Disease-associated mutations in CNGB3 promote cytotoxicity in photoreceptor-derived cells., Liu C,Sherpa T,Varnum MD, Mol Vis. June 11, 2013; 19:1090-0535.

ANKS6 is a central component of a nephronophthisis module linking NEK8 to INVS and NPHP3., Hoff S,Halbritter J,Epting D,Frank V,Nguyen TM,van Reeuwijk J,Boehlke C,Schell C,Yasunaga T,Helmstädter M,Mergen M,Filhol E,Boldt K,Horn N,Ueffing M,Otto EA,Eisenberger T,Elting MW,van Wijk JA,Bockenhauer D,Sebire NJ,Rittig S,Vyberg M,Ring T,Pohl M,Pape L,Neuhaus TJ,Elshakhs NA,Koon SJ,Harris PC,Grahammer F,Huber TB,Kuehn EW,Kramer-Zucker A,Bolz HJ,Roepman R,Saunier S,Walz G,Hildebrandt F,Bergmann C,Lienkamp SS, Nat Genet. August 1, 2013; 45(8):1546-1718.

Modeling human neurodevelopmental disorders in the Xenopus tadpole: from mechanisms to therapeutic targets., Pratt KG,Khakhalin AS, Dis Model Mech. September 1, 2013; 6(5):1754-8411.

Correction of mutations within the cystic fibrosis transmembrane conductance regulator by site-directed RNA editing., Montiel-Gonzalez MF,Vallecillo-Viejo I,Yudowski GA,Rosenthal JJ, Proc Natl Acad Sci U S A. November 5, 2013; 110(45):1091-6490.

Ciliogenesis and cerebrospinal fluid flow in the developing Xenopus brain are regulated by foxj1., Hagenlocher C,Walentek P,M Ller C,Thumberger T,Feistel K, Cilia. April 29, 2013; 2(1):2046-2530.

GRIN2B mutations in West syndrome and intellectual disability with focal epilepsy., Lemke JR,Hendrickx R,Geider K,Laube B,Schwake M,Harvey RJ,James VM,Pepler A,Steiner I,Hörtnagel K,Neidhardt J,Ruf S,Wolff M,Bartholdi D,Caraballo R,Platzer K,Suls A,De Jonghe P,Biskup S,Weckhuysen S, Ann Neurol. January 1, 2014; 75(1):1531-8249.

Characterization of SLC26A9 in patients with CF-like lung disease., Bakouh N,Bienvenu T,Thomas A,Ehrenfeld J,Liote H,Roussel D,Duquesnoy P,Farman N,Viel M,Cherif-Zahar B,Amselem S,Taam RA,Edelman A,Planelles G,Sermet-Gaudelus I, Hum Mutat. October 1, 2013; 34(10):1098-1004.

Essential roles of LEM-domain protein MAN1 during organogenesis in Xenopus laevis and overlapping functions of emerin., Reil M,Dabauvalle MC, Eur J Cell Biol. January 1, 2013; 92(8-9):0171-9335.

The heterotaxy gene GALNT11 glycosylates Notch to orchestrate cilia type and laterality., Boskovski MT,Yuan S,Pedersen NB,Goth CK,Makova S,Clausen H,Brueckner M,Khokha MK, Nature. December 19, 2013; 504(7480):0143-5221.

Cardiac expression and atrial fibrillation-associated remodeling of K₂p2.1 (TREK-1) K⁺ channels in a porcine model., Schmidt C,Wiedmann F,Tristram F,Anand P,Wenzel W,Lugenbiel P,Schweizer PA,Katus HA,Thomas D, Life Sci. March 3, 2014; 97(2):0024-3205.

The variant hERG/R148W associated with LQTS is a mutation that reduces current density on co-expression with the WT., Mechakra A,Vincent Y,Chevalier P,Millat G,Ficker E,Jastrzebski M,Poulin H,Pouliot V,Chahine M,Christé G, Gene. February 25, 2014; 536(2):1879-0038.

KCNJ10 mutations display differential sensitivity to heteromerisation with KCNJ16., Parrock S,Hussain S,Issler N,Differ AM,Lench N,Guarino S,Oosterveld MJ,Keijzer-Veen M,Brilstra E,van Wieringen H,Konijnenberg AY,Amin-Rasip S,Dumitriu S,Klootwijk E,Knoers N,Bockenhauer D,Kleta R,Zdebik AA, Nephron Physiol. January 1, 2013; 123(3-4):1660-2137.

Simple and efficient CRISPR/Cas9-mediated targeted mutagenesis in Xenopus tropicalis., Nakayama T,Fish MB,Fisher M,Oomen-Hajagos J,Thomsen GH,Grainger RM, Genesis. December 1, 2013; 51(12):1526-968X.

Functional characterization of an AQP0 missense mutation, R33C, that causes dominant congenital lens cataract, reveals impaired cell-to-cell adhesion., Kumari SS,Gandhi J,Mustehsan MH,Eren S,Varadaraj K, Exp Eye Res. November 1, 2013; 116:0014-4835.

Propofol modulation of α1 glycine receptors does not require a structural transition at adjacent subunits that is crucial to agonist-induced activation., Lynagh T,Kunz A,Laube B, ACS Chem Neurosci. November 20, 2013; 4(11):1948-7193.

The severe autosomal dominant retinitis pigmentosa rhodopsin mutant Ter349Glu mislocalizes and induces rapid rod cell death., Hollingsworth TJ,Gross AK, J Biol Chem. October 4, 2013; 288(40):1083-351X.

ZC88, a novel 4-amino piperidine analog, inhibits the growth of neuroblastoma cells through blocking hERG potassium channel., Wei X,Sun H,Yan H,Zhang C,Zhang S,Liu X,Hua N,Ma X,Zheng J, Cancer Biol Ther. May 1, 2013; 14(5):1555-8576.

ZMYND10 is mutated in primary ciliary dyskinesia and interacts with LRRC6., Zariwala MA,Gee HY,Kurkowiak M,Al-Mutairi DA,Leigh MW,Hurd TW,Hjeij R,Dell SD,Chaki M,Dougherty GW,Adan M,Spear PC,Esteve-Rudd J,Loges NT,Rosenfeld M,Diaz KA,Olbrich H,Wolf WE,Sheridan E,Batten TF,Halbritter J,Porath JD,Kohl S,Lovric S,Hwang DY,Pittman JE,Burns KA,Ferkol TW,Sagel SD,Olivier KN,Morgan LC,Werner C,Raidt J,Pennekamp P,Sun Z,Zhou W,Airik R,Natarajan S,Allen SJ,Amirav I,Wieczorek D,Landwehr K,Nielsen K,Schwerk N,Sertic J,Köhler G,Washburn J,Levy S,Fan S,Koerner-Rettberg C,Amselem S,Williams DS,Mitchell BJ,Drummond IA,Otto EA,Omran H,Knowles MR,Hildebrandt F, Am J Hum Genet. August 8, 2013; 93(2):1537-6605.

The retinal pigment epithelium: an important player of retinal disorders and regeneration., Chiba C, Exp Eye Res. June 1, 2014; 123:0014-4835.

Type 1 sodium-dependent phosphate transporter acts as a membrane potential-driven urate exporter., Miyaji T,Kawasaki T,Togawa N,Omote H,Moriyama Y, Curr Mol Pharmacol. July 1, 2013; 6(2):1874-4702.

A mutation in TGFB3 associated with a syndrome of low muscle mass, growth retardation, distal arthrogryposis and clinical features overlapping with Marfan and Loeys-Dietz syndrome., Rienhoff HY,Yeo CY,Morissette R,Khrebtukova I,Melnick J,Luo S,Leng N,Kim YJ,Schroth G,Westwick J,Vogel H,McDonnell N,Hall JG,Whitman M, Am J Med Genet A. August 1, 2013; 161A(8):1552-4833.

Transmembrane water-flux through SLC4A11: a route defective in genetic corneal diseases., Vilas GL,Loganathan SK,Liu J,Riau AK,Young JD,Mehta JS,Vithana EN,Casey JR, Hum Mol Genet. November 15, 2013; 22(22):1460-2083.

CNGA3 achromatopsia-associated mutation potentiates the phosphoinositide sensitivity of cone photoreceptor CNG channels by altering intersubunit interactions., Dai G,Varnum MD, Am J Physiol Cell Physiol. July 15, 2013; 305(2):1522-1563.

Generation and validation of a zebrafish model of EAST (epilepsy, ataxia, sensorineural deafness and tubulopathy) syndrome., Mahmood F,Mozere M,Zdebik AA,Stanescu HC,Tobin J,Beales PL,Kleta R,Bockenhauer D,Russell C, Dis Model Mech. May 1, 2013; 6(3):1754-8411.

Multi-functional norrin is a ligand for the LGR4 receptor., Deng C,Reddy P,Cheng Y,Luo CW,Hsiao CL,Hsueh AJ, J Cell Sci. May 1, 2013; 126(Pt 9):1477-9137.

Functional and electrophysiological characterization of four non-truncating mutations responsible for creatine transporter (SLC6A8) deficiency syndrome., Valayannopoulos V,Bakouh N,Mazzuca M,Nonnenmacher L,Hubert L,Makaci FL,Chabli A,Salomons GS,Mellot-Draznieks C,Brulé E,de Lonlay P,Toulhoat H,Munnich A,Planelles G,de Keyzer Y, J Inherit Metab Dis. January 1, 2013; 36(1):1573-2665.

Identification of compound heterozygous KCNJ1 mutations (encoding ROMK) in a kindred with Bartter's syndrome and a functional analysis of their pathogenicity., Srivastava S,Li D,Edwards N,Hynes AM,Wood K,Al-Hamed M,Wroe AC,Reaich D,Moochhala SH,Welling PA,Sayer JA, Physiol Rep. November 1, 2013; 1(6):2051-817X.

A potential molecular pathogenesis of cardiac/laterality defects in Oculo-Facio-Cardio-Dental syndrome., Tanaka K,Kato A,Angelocci C,Watanabe M,Kato Y, Dev Biol. March 1, 2014; 387(1):1095-564X.

The unusual stoichiometry of ADP activation of the KATP channel., Hosy E,Vivaudou M, Front Physiol. January 28, 2014; 5:1664-042X.

Fgfr signaling is required as the early eye field forms to promote later patterning and morphogenesis of the eye., Atkinson-Leadbeater K,Hehr CL,McFarlane S, Dev Dyn. May 1, 2014; :1058-8388.

Avermectins differentially affect ethanol intake and receptor function: implications for developing new therapeutics for alcohol use disorders., Asatryan L,Yardley MM,Khoja S,Trudell JR,Hyunh N,Louie SG,Petasis NA,Alkana RL,Davies DL, Int J Neuropsychopharmacol. June 1, 2014; 17(6):1469-5111.

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RFX7 is required for the formation of cilia in the neural tube., Manojlovic Z,Earwood R,Kato A,Stefanovic B,Kato Y, Mech Dev. May 1, 2014; 132:1872-6356.

PCP and septins compartmentalize cortical actomyosin to direct collective cell movement., Shindo A,Wallingford JB, Science. February 7, 2014; 343(6171):1095-9203.

The different effects on cranial and trunk neural crest cell behaviour following exposure to a low concentration of alcohol in vitro., Czarnobaj J,Bagnall KM,Bamforth JS,Milos NC, Arch Oral Biol. May 1, 2014; 59(5):1879-1506.

Heparanase 2, mutated in urofacial syndrome, mediates peripheral neural development in Xenopus., Roberts NA,Woolf AS,Stuart HM,Thuret R,McKenzie EA,Newman WG,Hilton EN, Hum Mol Genet. August 15, 2014; 23(16):1460-2083.

CHD7, the gene mutated in CHARGE syndrome, regulates genes involved in neural crest cell guidance., Schulz Y,Wehner P,Opitz L,Salinas-Riester G,Bongers EM,van Ravenswaaij-Arts CM,Wincent J,Schoumans J,Kohlhase J,Borchers A,Pauli S, Hum Genet. August 1, 2014; 133(8):1432-1203.

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A critical role of non-classical MHC in tumor immune evasion in the amphibian Xenopus model., Haynes-Gilmore N,Banach M,Edholm ES,Lord E,Robert J, Carcinogenesis. August 1, 2014; 35(8):1460-2180.

Mutations in CCNO result in congenital mucociliary clearance disorder with reduced generation of multiple motile cilia., Wallmeier J,Al-Mutairi DA,Chen CT,Loges NT,Pennekamp P,Menchen T,Ma L,Shamseldin HE,Olbrich H,Dougherty GW,Werner C,Alsabah BH,Köhler G,Jaspers M,Boon M,Griese M,Schmitt-Grohé S,Zimmermann T,Koerner-Rettberg C,Horak E,Kintner C,Alkuraya FS,Omran H, Nat Genet. June 1, 2014; 46(6):1546-1718.

Recessive mutations in PCBD1 cause a new type of early-onset diabetes., Simaite D,Kofent J,Gong M,Rüschendorf F,Jia S,Arn P,Bentler K,Ellaway C,Kühnen P,Hoffmann GF,Blau N,Spagnoli FM,Hübner N,Raile K, Diabetes. October 1, 2014; 63(10):1939-327X.

Retinoic acid induced-1 (Rai1) regulates craniofacial and brain development in Xenopus., Tahir R,Kennedy A,Elsea SH,Dickinson AJ, Mech Dev. August 1, 2014; 133:1872-6356.

miR-34/449 miRNAs are required for motile ciliogenesis by repressing cp110., Song R,Walentek P,Sponer N,Klimke A,Lee JS,Lee JS,Dixon G,Harland R,Wan Y,Lishko P,Lize M,Kessel M,He L, Nature. June 5, 2014; 510(7503):0143-5221.

A single codon insertion in PICALM is associated with development of familial subvalvular aortic stenosis in Newfoundland dogs., Stern JA,White SN,Lehmkuhl LB,Reina-Doreste Y,Ferguson JL,Nascone-Yoder NM,Meurs KM, Hum Genet. September 1, 2014; 133(9):1432-1203.

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Congenital ataxia and hemiplegic migraine with cerebral edema associated with a novel gain of function mutation in the calcium channel CACNA1A., García Segarra N,Gautschi I,Mittaz-Crettol L,Kallay Zetchi C,Al-Qusairi L,Van Bemmelen MX,Maeder P,Bonafé L,Schild L,Roulet-Perez E, J Neurol Sci. July 15, 2014; 342(1-2):1878-5883.

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The molecular mechanism of intestinal levodopa absorption and its possible implications for the treatment of Parkinson's disease., Camargo SM,Vuille-dit-Bille RN,Mariotta L,Ramadan T,Huggel K,Singer D,Götze O,Verrey F, J Pharmacol Exp Ther. October 1, 2014; 351(1):1521-0103.

The extreme anterior domain is an essential craniofacial organizer acting through Kinin-Kallikrein signaling., Jacox L,Sindelka R,Chen J,Rothman A,Dickinson A,Sive H, Cell Rep. July 24, 2014; 8(2):2211-1247.

Cystic fibrosis transmembrane conductance regulator (CFTR) potentiators protect G551D but not ΔF508 CFTR from thermal instability., Liu X,Dawson DC, Biochemistry. September 9, 2014; 53(35):1520-4995.

The prostaglandin EP1 receptor potentiates kainate receptor activation via a protein kinase C pathway and exacerbates status epilepticus., Rojas A,Gueorguieva P,Lelutiu N,Quan Y,Shaw R,Dingledine R, Neurobiol Dis. October 1, 2014; 70:1095-953X.

FANCJ promotes DNA synthesis through G-quadruplex structures., Castillo Bosch P,Segura-Bayona S,Koole W,van Heteren JT,Dewar JM,Tijsterman M,Knipscheer P, EMBO J. November 3, 2014; 33(21):0261-4189.

5-Mehtyltetrahydrofolate rescues alcohol-induced neural crest cell migration abnormalities., Shi Y,Shi Y,Li J,Chen C,Gong M,Chen Y,Chen Y,Liu Y,Chen J,Li T,Song W, Mol Brain. September 16, 2014; 7:1756-6606.

The splicing factor PQBP1 regulates mesodermal and neural development through FGF signaling., Iwasaki Y,Thomsen GH, Development. October 1, 2014; 141(19):1477-9129.

Aberrant connexin26 hemichannels underlying keratitis-ichthyosis-deafness syndrome are potently inhibited by mefloquine., Levit NA,Sellitto C,Wang HZ,Li L,Srinivas M,Brink PR,White TW, J Invest Dermatol. April 1, 2015; 135(4):1523-1747.

Inhibitory effects of insulin on GABAA currents modulated by the GABAA alpha subunit., Williams DB, J Recept Signal Transduct Res. January 1, 2015; 35(6):1532-4281.

Cathepsin B contributes to Na+ hyperabsorption in cystic fibrosis airway epithelial cultures., Tan CD,Hobbs C,Sameni M,Sloane BF,Stutts MJ,Tarran R, J Physiol. December 1, 2014; 592(23):0022-3751.

Mutations in the voltage-gated potassium channel gene KCNH1 cause Temple-Baraitser syndrome and epilepsy., Simons C,Rash LD,Crawford J,Ma L,Cristofori-Armstrong B,Miller D,Ru K,Baillie GJ,Alanay Y,Jacquinet A,Debray FG,Verloes A,Shen J,Yesil G,Guler S,Yuksel A,Cleary JG,Grimmond SM,McGaughran J,King GF,Gabbett MT,Taft RJ, Nat Genet. January 1, 2015; 47(1):1546-1718.

Effect of the CALHM1 G330D and R154H human variants on the control of cytosolic Ca2+ and Aβ levels., Vingtdeux V,Tanis JE,Chandakkar P,Zhao H,Dreses-Werringloer U,Campagne F,Foskett JK,Marambaud P, PLoS One. November 6, 2014; 9(11):1932-6203.

Properties, regulation, pharmacology, and functions of the K₂p channel, TRESK., Enyedi P,Czirják G, Pflugers Arch. May 1, 2015; 467(5):1432-2013.

Isoquercitrin suppresses colon cancer cell growth in vitro by targeting the Wnt/β-catenin signaling pathway., Amado NG,Predes D,Fonseca BF,Cerqueira DM,Reis AH,Dudenhoeffer AC,Borges HL,Mendes FA,Abreu JG, J Biol Chem. December 19, 2014; 289(51):1083-351X.

Photoactivation-induced instability of rhodopsin mutants T4K and T17M in rod outer segments underlies retinal degeneration in X. laevis transgenic models of retinitis pigmentosa., Tam BM,Noorwez SM,Kaushal S,Kono M,Moritz OL, J Neurosci. October 1, 2014; 34(40):1529-2401.

Xenopus mutant reveals necessity of rax for specifying the eye field which otherwise forms tissue with telencephalic and diencephalic character., Fish MB,Nakayama T,Fisher M,Hirsch N,Cox A,Reeder R,Carruthers S,Hall A,Stemple DL,Grainger RM, Dev Biol. November 15, 2014; 395(2):1095-564X.

The bile acid receptor TGR5 activates the TRPA1 channel to induce itch in mice., Lieu T,Jayaweera G,Zhao P,Poole DP,Jensen D,Grace M,McIntyre P,Bron R,Wilson YM,Krappitz M,Haerteis S,Korbmacher C,Steinhoff MS,Nassini R,Materazzi S,Geppetti P,Corvera CU,Bunnett NW, Gastroenterology. December 1, 2014; 147(6):1528-0012.

Cloning, functional characterization, and remodeling of K2P3.1 (TASK-1) potassium channels in a porcine model of atrial fibrillation and heart failure., Schmidt C,Wiedmann F,Langer C,Tristram F,Anand P,Wenzel W,Lugenbiel P,Schweizer PA,Katus HA,Thomas D, Heart Rhythm. October 1, 2014; 11(10):1547-5271.

Moving gating charges through the gating pore in a Kv channel voltage sensor., Lacroix JJ,Hyde HC,Campos FV,Bezanilla F, Proc Natl Acad Sci U S A. May 13, 2014; 111(19):1091-6490.

Stoichiometry and specific assembly of Best ion channels., Bharill S,Fu Z,Palty R,Isacoff EY, Proc Natl Acad Sci U S A. April 29, 2014; 111(17):1091-6490.

A missense mutation accelerating the gating of the lysosomal Cl-/H+-exchanger ClC-7/Ostm1 causes osteopetrosis with gingival hamartomas in cattle., Sartelet A,Stauber T,Coppieters W,Ludwig CF,Fasquelle C,Druet T,Zhang Z,Zhang Z,Zhang Z,Ahariz N,Cambisano N,Jentsch TJ,Charlier C, Dis Model Mech. January 1, 2014; 7(1):1754-8411.

A Gro/TLE-NuRD corepressor complex facilitates Tbx20-dependent transcriptional repression., Kaltenbrun E,Greco TM,Slagle CE,Kennedy LM,Li T,Cristea IM,Conlon FL, J Proteome Res. December 6, 2013; 12(12):1535-3907.

Insights on the mechanisms of Ca(2+) regulation of connexin26 hemichannels revealed by human pathogenic mutations (D50N/Y)., Lopez W,Gonzalez J,Liu Y,Harris AL,Contreras JE, J Gen Physiol. July 1, 2013; 142(1):1540-7748.

The cataract and glucosuria associated monocarboxylate transporter MCT12 is a new creatine transporter., Abplanalp J,Laczko E,Philp NJ,Neidhardt J,Zuercher J,Braun P,Schorderet DF,Munier FL,Verrey F,Berger W,Camargo SM,Kloeckener-Gruissem B, Hum Mol Genet. August 15, 2013; 22(16):1460-2083.

Distinct patterns of compartmentalization and proteolytic stability of PDE6C mutants linked to achromatopsia., Cheguru P,Majumder A,Artemyev NO, Mol Cell Neurosci. January 1, 2015; 64:1044-7431.

Long-range gap junctional signaling controls oncogene-mediated tumorigenesis in Xenopus laevis embryos., Chernet BT,Fields C,Levin M, Front Physiol. January 19, 2015; 5:1664-042X.

Semi-solid tumor model in Xenopus laevis/gilli cloned tadpoles for intravital study of neovascularization, immune cells and melanophore infiltration., Haynes-Gimore N,Banach M,Brown E,Dawes R,Edholm ES,Kim M,Robert J, Dev Biol. December 15, 2015; 408(2):1095-564X.

The Rac1 regulator ELMO controls basal body migration and docking in multiciliated cells through interaction with Ezrin., Epting D,Slanchev K,Boehlke C,Hoff S,Loges NT,Yasunaga T,Indorf L,Nestel S,Lienkamp SS,Omran H,Kuehn EW,Ronneberger O,Walz G,Kramer-Zucker A, Development. January 1, 2015; 142(1):1477-9129.

R-(+) and S-(-) isomers of cotinine augment cholinergic responses in vitro and in vivo., Terry AV,Callahan PM,Bertrand D, J Pharmacol Exp Ther. February 1, 2015; 352(2):1521-0103.

A functional correlate of severity in alternating hemiplegia of childhood., Li M,Jazayeri D,Corry B,McSweeney KM,Heinzen EL,Goldstein DB,Petrou S, Neurobiol Dis. May 1, 2015; 77:1095-953X.

A recurrent de novo mutation in KCNC1 causes progressive myoclonus epilepsy., Muona M,Berkovic SF,Dibbens LM,Oliver KL,Maljevic S,Bayly MA,Joensuu T,Canafoglia L,Franceschetti S,Michelucci R,Markkinen S,Heron SE,Hildebrand MS,Andermann E,Andermann F,Gambardella A,Tinuper P,Licchetta L,Scheffer IE,Criscuolo C,Filla A,Ferlazzo E,Ahmad J,Ahmad A,Baykan B,Said E,Topcu M,Riguzzi P,King MD,Ozkara C,Andrade DM,Engelsen BA,Crespel A,Lindenau M,Lohmann E,Saletti V,Massano J,Privitera M,Espay AJ,Kauffmann B,Duchowny M,Møller RS,Straussberg R,Afawi Z,Ben-Zeev B,Samocha KE,Daly MJ,Petrou S,Lerche H,Palotie A,Lehesjoki AE, Nat Genet. January 1, 2015; 47(1):1546-1718.

TASK-1 and TASK-3 may form heterodimers in human atrial cardiomyocytes., Rinné S,Kiper AK,Schlichthörl G,Dittmann S,Netter MF,Limberg SH,Silbernagel N,Zuzarte M,Moosdorf R,Wulf H,Schulze-Bahr E,Rolfes C,Decher N, J Mol Cell Cardiol. April 1, 2015; 81:1095-8584.

Loss of functional endothelial connexin40 results in exercise-induced hypertension in mice., Morton SK,Chaston DJ,Howitt L,Heisler J,Nicholson BJ,Fairweather S,Bröer S,Ashton AW,Matthaei KI,Hill CE, Hypertension. March 1, 2015; 65(3):1524-4563.

Using Xenopus tissue cultures for the study of myasthenia gravis pathogenesis., Yeo HL,Lim JY,Fukami Y,Yuki N,Lee CW,Lee CW,Lee CW, Dev Biol. December 15, 2015; 408(2):1095-564X.

More similar than you think: Frog metamorphosis as a model of human perinatal endocrinology., Buchholz DR, Dev Biol. December 15, 2015; 408(2):1095-564X.

Derricin and derricidin inhibit Wnt/β-catenin signaling and suppress colon cancer cell growth in vitro., Fonseca BF,Predes D,Cerqueira DM,Reis AH,Amado NG,Cayres MC,Kuster RM,Oliveira FL,Mendes FA,Abreu JG, PLoS One. March 16, 2015; 10(3):1932-6203.

Ascl1 phospho-status regulates neuronal differentiation in a Xenopus developmental model of neuroblastoma., Wylie LA,Hardwick LJ,Papkovskaia TD,Thiele CJ,Philpott A, Dis Model Mech. May 1, 2015; 8(5):1754-8411.

Osmostress-induced apoptosis in Xenopus oocytes: role of stress protein kinases, calpains and Smac/DIABLO., Ben Messaoud N,Yue J,Valent D,Katzarova I,López JM, PLoS One. January 1, 2015; 10(4):1932-6203.

ATP4a is required for development and function of the Xenopus mucociliary epidermis - a potential model to study proton pump inhibitor-associated pneumonia., Walentek P,Beyer T,Hagenlocher C,Müller C,Feistel K,Schweickert A,Harland RM,Blum M, Dev Biol. December 15, 2015; 408(2):1095-564X.

Xenopus pax6 mutants affect eye development and other organ systems, and have phenotypic similarities to human aniridia patients., Nakayama T,Fisher M,Fisher M,Nakajima K,Odeleye AO,Zimmerman KB,Zimmerman KB,Fish MB,Yaoita Y,Chojnowski JL,Lauderdale JD,Netland PA,Grainger RM, Dev Biol. December 15, 2015; 408(2):1095-564X.

Molecular mechanism of CHRDL1-mediated X-linked megalocornea in humans and in Xenopus model., Pfirrmann T,Emmerich D,Ruokonen P,Quandt D,Buchen R,Fischer-Zirnsak B,Hecht J,Krawitz P,Meyer P,Klopocki E,Stricker S,Lausch E,Seliger B,Hollemann T,Reinhard T,Auw-Haedrich C,Zabel B,Hoffmann K,Villavicencio-Lorini P, Hum Mol Genet. June 1, 2015; 24(11):1460-2083.

An oncologist׳s friend: How Xenopus contributes to cancer research., Hardwick LJ,Philpott A, Dev Biol. December 15, 2015; 408(2):1095-564X.

Valproate-induced neurodevelopmental deficits in Xenopus laevis tadpoles., James EJ,Gu J,Ramirez-Vizcarrondo CM,Hasan M,Truszkowski TL,Tan Y,Oupravanh PM,Khakhalin AS,Aizenman CD, J Neurosci. February 18, 2015; 35(7):1529-2401.

A role for BMP-induced homeobox gene MIXL1 in acute myelogenous leukemia and identification of type I BMP receptor as a potential target for therapy., Raymond A,Liu B,Liang H,Wei C,Guindani M,Lu Y,Liang S,St John LS,Molldrem J,Nagarajan L, Oncotarget. December 30, 2014; 5(24):1949-2553.

Hyperkalemic hypertension-associated cullin 3 promotes WNK signaling by degrading KLHL3., McCormick JA,Yang CL,Zhang C,Davidge B,Blankenstein KI,Terker AS,Yarbrough B,Meermeier NP,Park HJ,McCully B,West M,Borschewski A,Himmerkus N,Bleich M,Bachmann S,Mutig K,Argaiz ER,Gamba G,Singer JD,Ellison DH, J Clin Invest. November 1, 2014; 124(11):1558-8238.

Nav1.1 modulation by a novel triazole compound attenuates epileptic seizures in rodents., Gilchrist J,Dutton S,Diaz-Bustamante M,McPherson A,Olivares N,Kalia J,Escayg A,Bosmans F, ACS Chem Biol. May 16, 2014; 9(5):1554-8937.

Mutating a conserved proline residue within the trimerization domain modifies Na+ binding to excitatory amino acid transporters and associated conformational changes., Hotzy J,Schneider N,Kovermann P,Fahlke C, J Biol Chem. December 20, 2013; 288(51):1083-351X.

Stereoselective inhibition of serotonin transporters by antimalarial compounds., Beckman ML,Pramod AB,Perley D,Henry LK, Neurochem Int. July 1, 2014; 73:1872-9754.

Heterologous expression of NaV1.9 chimeras in various cell systems., Goral RO,Leipold E,Nematian-Ardestani E,Heinemann SH, Pflugers Arch. December 1, 2015; 467(12):1432-2013.

Remyelination by Resident Oligodendrocyte Precursor Cells in a Xenopus laevis Inducible Model of Demyelination., Sekizar S,Mannioui A,Azoyan L,Colin C,Thomas JL,Du Pasquier D,Mallat M,Zalc B, Dev Neurosci. January 1, 2015; 37(3):1421-9859.

The evolutionarily conserved transcription factor PRDM12 controls sensory neuron development and pain perception., Nagy V,Cole T,Van Campenhout C,Khoung TM,Leung C,Vermeiren S,Novatchkova M,Wenzel D,Cikes D,Polyansky AA,Kozieradzki I,Meixner A,Bellefroid EJ,Neely GG,Penninger JM, Cell Cycle. January 1, 2015; 14(12):1551-4005.

Genetically induced dysfunctions of Kir2.1 channels: implications for short QT3 syndrome and autism-epilepsy phenotype., Ambrosini E,Sicca F,Brignone MS,D'Adamo MC,Napolitano C,Servettini I,Moro F,Ruan Y,Guglielmi L,Pieroni S,Servillo G,Lanciotti A,Valvo G,Catacuzzeno L,Franciolini F,Molinari P,Marchese M,Grottesi A,Guerrini R,Santorelli FM,Priori S,Pessia M, Hum Mol Genet. September 15, 2014; 23(18):1460-2083.

Follicle Online: an integrated database of follicle assembly, development and ovulation., Hua J,Xu B,Yang Y,Yang Y,Ban R,Iqbal F,Cooke HJ,Zhang Y,Zhang Y,Shi Q, Database (Oxford). April 29, 2015; 2015:1758-0463.

State-dependent network connectivity determines gating in a K+ channel., Bollepalli MK,Fowler PW,Rapedius M,Shang L,Sansom MS,Tucker SJ,Baukrowitz T, Structure. July 8, 2014; 22(7):1878-4186.

Transcriptional regulator PRDM12 is essential for human pain perception., Chen YC,Chen YC,Auer-Grumbach M,Matsukawa S,Zitzelsberger M,Themistocleous AC,Strom TM,Samara C,Moore AW,Cho LT,Young GT,Weiss C,Schabhüttl M,Stucka R,Schmid AB,Parman Y,Graul-Neumann L,Heinritz W,Passarge E,Watson RM,Hertz JM,Moog U,Baumgartner M,Valente EM,Pereira D,Restrepo CM,Katona I,Dusl M,Stendel C,Wieland T,Stafford F,Reimann F,von Au K,Finke C,Willems PJ,Nahorski MS,Shaikh SS,Carvalho OP,Nicholas AK,Karbani G,McAleer MA,Cilio MR,McHugh JC,Murphy SM,Irvine AD,Jensen UB,Windhager R,Weis J,Bergmann C,Rautenstrauss B,Baets J,De Jonghe P,Reilly MM,Kropatsch R,Kurth I,Chrast R,Michiue T,Bennett DL,Woods CG,Senderek J, Nat Genet. July 1, 2015; 47(7):1546-1718.

Autosomal-Recessive Mutations in SLC34A1 Encoding Sodium-Phosphate Cotransporter 2A Cause Idiopathic Infantile Hypercalcemia., Schlingmann KP,Ruminska J,Kaufmann M,Dursun I,Patti M,Kranz B,Pronicka E,Ciara E,Akcay T,Bulus D,Cornelissen EA,Gawlik A,Sikora P,Patzer L,Galiano M,Boyadzhiev V,Dumic M,Vivante A,Kleta R,Dekel B,Levtchenko E,Bindels RJ,Rust S,Forster IC,Hernando N,Jones G,Wagner CA,Konrad M, J Am Soc Nephrol. February 1, 2016; 27(2):1533-3450.

Structure-activity analysis of a CFTR channel potentiator: Distinct molecular parts underlie dual gating effects., Csanády L,Töröcsik B, J Gen Physiol. October 1, 2014; 144(4):1540-7748.

Regulation of the Rev1-pol ζ complex during bypass of a DNA interstrand cross-link., Budzowska M,Graham TG,Sobeck A,Waga S,Walter JC, EMBO J. July 14, 2015; 34(14):0261-4189.

High incidence of functional ion-channel abnormalities in a consecutive Long QT cohort with novel missense genetic variants of unknown significance., Steffensen AB,Refaat MM,David JP,Mujezinovic A,Calloe K,Wojciak J,Nussbaum RL,Scheinman MM,Schmitt N, Sci Rep. January 12, 2015; 5:2045-2322.

Three charged amino acids in extracellular loop 1 are involved in maintaining the outer pore architecture of CFTR., Cui G,Rahman KS,Infield DT,Kuang C,Prince CZ,McCarty NA, J Gen Physiol. August 1, 2014; 144(2):1540-7748.

Disrupted coupling of gating charge displacement to Na+ current activation for DIIS4 mutations in hypokalemic periodic paralysis., Mi W,Rybalchenko V,Cannon SC, J Gen Physiol. August 1, 2014; 144(2):1540-7748.

The involvement of PCP proteins in radial cell intercalations during Xenopus embryonic development., Ossipova O,Chu CW,Fillatre J,Brott BK,Itoh K,Sokol SY, Dev Biol. December 15, 2015; 408(2):1095-564X.

BMP signalling controls the construction of vertebrate mucociliary epithelia., Cibois M,Luxardi G,Chevalier B,Thomé V,Mercey O,Zaragosi LE,Barbry P,Pasini A,Marcet B,Kodjabachian L, Development. July 1, 2015; 142(13):1477-9129.

TALEN-mediated apc mutation in Xenopus tropicalis phenocopies familial adenomatous polyposis., Van Nieuwenhuysen T,Naert T,Tran HT,Van Imschoot G,Geurs S,Sanders E,Creytens D,Van Roy F,Vleminckx K,Vleminckx K, Oncoscience. May 19, 2015; 2(5):2331-4737.

9B.03: A NOVEL INSERTIONAL SOMATIC KCNJ5 MUTATION IN AN AUSTRALIAN PATIENT WITH AN ALDOSTERONE PRODUCING ADENOMA., Xu S,Hardege I,Murthy M,Gordon R,Stowasser M,OʼShaughnessy K, J Hypertens. June 1, 2015; 33 Suppl 1:1473-5598.

PnPP-19, a Synthetic and Nontoxic Peptide Designed from a Phoneutria nigriventer Toxin, Potentiates Erectile Function via NO/cGMP., Silva CN,Nunes KP,Torres FS,Cassoli JS,Santos DM,Almeida Fde M,Matavel A,Cruz JS,Santos-Miranda A,Nunes AD,Castro CH,Machado de Ávila RA,Chávez-Olórtegui C,Láuar SS,Felicori L,Resende JM,Camargos ER,Borges MH,Cordeiro MN,Peigneur S,Tytgat J,de Lima ME, J Urol. November 1, 2015; 194(5):1527-3792.

Molecular asymmetry in the 8-cell stage Xenopus tropicalis embryo described by single blastomere transcript sequencing., De Domenico E,Owens ND,Grant IM,Gomes-Faria R,Gilchrist MJ, Dev Biol. December 15, 2015; 408(2):1095-564X.

Developmental role of plk4 in Xenopus laevis and Danio rerio: implications for Seckel Syndrome., Rapchak CE,Patel N,Hudson J,Crawford M, Biochem Cell Biol. August 1, 2015; 93(4):1208-6002.

The role of folate metabolism in orofacial development and clefting., Wahl SE,Kennedy AE,Wyatt BH,Moore AD,Pridgen DE,Cherry AM,Mavila CB,Dickinson AJ, Dev Biol. September 1, 2015; 405(1):1095-564X.

The UNC-45 myosin chaperone: from worms to flies to vertebrates., Lee CF,Lee CF,Lee CF,Melkani GC,Bernstein SI, Int Rev Cell Mol Biol. January 1, 2014; 313:1937-6448.

GABAA currents are decreased by IL-1β in epileptogenic tissue of patients with temporal lobe epilepsy: implications for ictogenesis., Roseti C,van Vliet EA,Cifelli P,Ruffolo G,Baayen JC,Di Castro MA,Bertollini C,Limatola C,Aronica E,Vezzani A,Palma E, Neurobiol Dis. October 1, 2015; 82:1095-953X.

ADAM13 cleavage of cadherin-11 promotes CNC migration independently of the homophilic binding site., Abbruzzese G,Becker SF,Kashef J,Alfandari D,Alfandari D, Dev Biol. July 15, 2016; 415(2):1095-564X.

The N-methyl-D-aspartate receptor's neglected subunit - GluN1 matters under normal and hyperbaric conditions., Bliznyuk A,Aviner B,Golan H,Hollmann M,Grossman Y, Eur J Neurosci. October 1, 2015; 42(8):1460-9568.

Novel BCOR mutation in a boy with Lenz microphthalmia/oculo-facio-cardio-dental (OFCD) syndrome., Zhu X,Dai FR,Wang J,Zhang Y,Zhang Y,Tan ZP,Zhang Y,Zhang Y, Gene. October 15, 2015; 571(1):1879-0038.

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Xenopus as a Model for GI/Pancreas Disease., Salanga MC,Horb ME, Curr Pathobiol Rep. June 1, 2015; 3(2):2167-485X.

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A Disease Mutation Causing Episodic Ataxia Type I in the S1 Links Directly to the Voltage Sensor and the Selectivity Filter in Kv Channels., Petitjean D,Kalstrup T,Zhao J,Blunck R, J Neurosci. September 2, 2015; 35(35):1529-2401.

Analyzing and Modeling the Kinetics of Amyloid Beta Pores Associated with Alzheimer's Disease Pathology., Ullah G,Demuro A,Parker I,Pearson JE, PLoS One. September 4, 2015; 10(9):1932-6203.

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Mutations in GRIN2A cause idiopathic focal epilepsy with rolandic spikes., Lemke JR,Lal D,Reinthaler EM,Steiner I,Nothnagel M,Alber M,Geider K,Laube B,Schwake M,Finsterwalder K,Franke A,Schilhabel M,Jähn JA,Muhle H,Boor R,Van Paesschen W,Caraballo R,Fejerman N,Weckhuysen S,De Jonghe P,Larsen J,Møller RS,Hjalgrim H,Addis L,Tang S,Hughes E,Pal DK,Veri K,Vaher U,Talvik T,Dimova P,Guerrero López R,Serratosa JM,Linnankivi T,Lehesjoki AE,Ruf S,Wolff M,Buerki S,Wohlrab G,Kroell J,Datta AN,Fiedler B,Kurlemann G,Kluger G,Hahn A,Haberlandt DE,Kutzer C,Sperner J,Becker F,Weber YG,Feucht M,Steinböck H,Neophythou B,Ronen GM,Gruber-Sedlmayr U,Geldner J,Harvey RJ,Hoffmann P,Herms S,Altmüller J,Toliat MR,Thiele H,Nürnberg P,Wilhelm C,Stephani U,Helbig I,Lerche H,Zimprich F,Neubauer BA,Biskup S,von Spiczak S, Nat Genet. September 1, 2013; 45(9):1546-1718.

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Xenopus laevis as a Model to Identify Translation Impairment., de Broucker A,Semaille P,Cailliau K,Martoriati A,Comptdaer T,Bodart JF,Destée A,Chartier-Harlin MC, J Vis Exp. September 27, 2015; (103):1940-087X.

Identifying Regulators of Morphogenesis Common to Vertebrate Neural Tube Closure and Caenorhabditis elegans Gastrulation., Sullivan-Brown JL,Tandon P,Bird KE,Dickinson DJ,Tintori SC,Heppert JK,Meserve JH,Trogden KP,Orlowski SK,Conlon FL,Goldstein B, Genetics. January 1, 2016; 202(1):1943-2631.

Activation of TRPV1 channels inhibits mechanosensitive Piezo channel activity by depleting membrane phosphoinositides., Borbiro I,Badheka D,Rohacs T, Sci Signal. February 10, 2015; 8(363):1937-9145.

The NIMA-like kinase Nek2 is a key switch balancing cilia biogenesis and resorption in the development of left-right asymmetry., Endicott SJ,Basu B,Khokha M,Brueckner M, Development. December 1, 2015; 142(23):1477-9129.

Identification and Functional Characterization of CLCN1 Mutations Found in Nondystrophic Myotonia Patients., Vindas-Smith R,Fiore M,Vásquez M,Cuenca P,Del Valle G,Lagostena L,Gaitán-Peñas H,Estevez R,Pusch M,Morales F, Hum Mutat. January 1, 2016; 37(1):1098-1004.

A channelopathy mechanism revealed by direct calmodulin activation of TrpV4., Loukin SH,Teng J,Kung C, Proc Natl Acad Sci U S A. July 28, 2015; 112(30):1091-6490.

CRISPR/Cas9: An inexpensive, efficient loss of function tool to screen human disease genes in Xenopus., Bhattacharya D,Marfo CA,Li D,Lane M,Khokha MK, Dev Biol. December 15, 2015; 408(2):1095-564X.

Ptbp1 and Exosc9 knockdowns trigger skin stability defects through different pathways., Noiret M,Mottier S,Angrand G,Gautier-Courteille C,Lerivray H,Viet J,Paillard L,Mereau A,Hardy S,Audic Y, Dev Biol. January 15, 2016; 409(2):1095-564X.

Deletions and de novo mutations of SOX11 are associated with a neurodevelopmental disorder with features of Coffin-Siris syndrome., Hempel A,Pagnamenta AT,Blyth M,Mansour S,McConnell V,Kou I,Ikegawa S,Tsurusaki Y,Matsumoto N,Lo-Castro A,Plessis G,Albrecht B,Battaglia A,Taylor JC,Howard MF,Keays D,Sohal AS,Kühl SJ,Kühl SJ,Kini U,McNeill A, J Med Genet. March 1, 2016; 53(3):1468-6244.

Ccdc11 is a novel centriolar satellite protein essential for ciliogenesis and establishment of left-right asymmetry., Silva E,Betleja E,John E,Spear P,Moresco JJ,Zhang S,Yates JR,Mitchell BJ,Mahjoub MR, Mol Biol Cell. January 1, 2016; 27(1):1939-4586.

The Effect of WNK4 on the Na+-Cl- Cotransporter Is Modulated by Intracellular Chloride., Bazúa-Valenti S,Chávez-Canales M,Rojas-Vega L,González-Rodríguez X,Vázquez N,Rodríguez-Gama A,Argaiz ER,Melo Z,Plata C,Ellison DH,García-Valdés J,Hadchouel J,Gamba G, J Am Soc Nephrol. August 1, 2015; 26(8):1533-3450.

Channelopathies: ion channel defects linked to heritable clinical disorders., Felix R, J Med Genet. October 1, 2000; 37(10):1468-6244.

Distinctive effects of nicotinic receptor intracellular-loop mutations associated with nocturnal frontal lobe epilepsy., Weltzin MM,Lindstrom JM,Lukas RJ,Whiteaker P, Neuropharmacology. March 1, 2016; 102:1873-7064.

Alternative splice variant of the thiazide-sensitive NaCl cotransporter: a novel player in renal salt handling., Tutakhel OA,Jeleń S,Valdez-Flores M,Dimke H,Piersma SR,Jimenez CR,Deinum J,Lenders JW,Hoenderop JG,Bindels RJ, Am J Physiol Renal Physiol. February 1, 2016; 310(3):1522-1466.

RNA-Seq and microarray analysis of the Xenopus inner ear transcriptome discloses orthologous OMIM(®) genes for hereditary disorders of hearing and balance., Ramírez-Gordillo D,Powers TR,van Velkinburgh JC,Trujillo-Provencio C,Schilkey F,Serrano EE, BMC Res Notes. November 18, 2015; 8:1756-0500.

Specific transport of 3-fluoro-l-α-methyl-tyrosine by LAT1 explains its specificity to malignant tumors in imaging., Wei L,Tominaga H,Ohgaki R,Wiriyasermkul P,Hagiwara K,Okuda S,Kaira K,Oriuchi N,Nagamori S,Kanai Y, Cancer Sci. March 1, 2016; 107(3):1349-7006.

Xenopus as a model system for studying pancreatic development and diabetes., Kofent J,Spagnoli FM, Semin Cell Dev Biol. March 1, 2016; 51:1096-3634.

Using frogs faces to dissect the mechanisms underlying human orofacial defects., Dickinson AJ, Semin Cell Dev Biol. March 1, 2016; 51:1096-3634.

Using Xenopus to study genetic kidney diseases., Lienkamp SS, Semin Cell Dev Biol. March 1, 2016; 51:1096-3634.

Sf3b4-depleted Xenopus embryos: A model to study the pathogenesis of craniofacial defects in Nager syndrome., Devotta A,Juraver-Geslin H,Gonzalez JA,Hong CS,Saint-Jeannet JP, Dev Biol. July 15, 2016; 415(2):1095-564X.

Iron Overload Leading to Torsades de Pointes in β-Thalassemia and Long QT Syndrome., Refaat MM,El Hage L,Steffensen AB,Hotait M,Schmitt N,Scheinman M,Badhwar N, Card Electrophysiol Clin. March 1, 2016; 8(1):1877-9190.

Polyunsaturated fatty acids are potent openers of human M-channels expressed in Xenopus laevis oocytes., Liin SI,Karlsson U,Bentzen BH,Schmitt N,Elinder F, Acta Physiol (Oxf). September 1, 2016; 218(1):1748-1716.

Xenopus as a model organism for birth defects-Congenital heart disease and heterotaxy., Duncan AR,Khokha MK, Semin Cell Dev Biol. March 1, 2016; 51:1096-3634.

Acetylcholine receptors from human muscle as pharmacological targets for ALS therapy., Palma E,Reyes-Ruiz JM,Lopergolo D,Roseti C,Bertollini C,Ruffolo G,Cifelli P,Onesti E,Limatola C,Miledi R,Inghilleri M, Proc Natl Acad Sci U S A. March 15, 2016; 113(11):1091-6490.

Efficient Activation of Pathogenic ΔPhe501 Mutation in Monocarboxylate Transporter 8 by Chemical and Pharmacological Chaperones., Braun D,Schweizer U, Endocrinology. December 1, 2015; 156(12):1945-7170.

Identification of anti-cancer chemical compounds using Xenopus embryos., Tanaka M,Kuriyama S,Itoh G,Kohyama A,Iwabuchi Y,Shibata H,Yashiro M,Aiba N, Cancer Sci. June 1, 2016; 107(6):1349-7006.

A pure chloride channel mutant of CLC-5 causes Dent's disease via insufficient V-ATPase activation., Satoh N,Yamada H,Yamazaki O,Suzuki M,Suzuki M,Nakamura M,Suzuki A,Ashida A,Yamamoto D,Kaku Y,Sekine T,Seki G,Horita S, Pflugers Arch. July 1, 2016; 468(7):1432-2013.

Successful transfer to sulfonylureas in KCNJ11 neonatal diabetes is determined by the mutation and duration of diabetes., Babiker T,Vedovato N,Patel K,Thomas N,Finn R,Männikkö R,Chakera AJ,Flanagan SE,Shepherd MH,Ellard S,Ashcroft FM,Hattersley AT, Diabetologia. June 1, 2016; 59(6):1432-0428.

Musculocontractural Ehlers-Danlos syndrome and neurocristopathies: dermatan sulfate is required for Xenopus neural crest cells to migrate and adhere to fibronectin., Gouignard N,Maccarana M,Strate I,von Stedingk K,Malmström A,Pera EM, Dis Model Mech. June 1, 2016; 9(6):1754-8411.

The search for NKCC1-selective drugs for the treatment of epilepsy: Structure-function relationship of bumetanide and various bumetanide derivatives in inhibiting the human cation-chloride cotransporter NKCC1A., Lykke K,Töllner K,Feit PW,Erker T,MacAulay N,Löscher W, Epilepsy Behav. June 1, 2016; 59:1525-5069.

The cataract related mutation N188T in human connexin46 (hCx46) revealed a critical role for residue N188 in the docking process of gap junction channels., Schadzek P,Schlingmann B,Schaarschmidt F,Lindner J,Koval M,Heisterkamp A,Preller M,Ngezahayo A, Biochim Biophys Acta. January 1, 2016; 1858(1):0006-3002.

WNT16 antagonises excessive canonical WNT activation and protects cartilage in osteoarthritis., Nalesso G,Thomas BL,Sherwood JC,Yu J,Addimanda O,Eldridge SE,Thorup AS,Dale L,Schett G,Zwerina J,Eltawil N,Pitzalis C,Dell'Accio F, Ann Rheum Dis. January 1, 2017; 76(1):1468-2060.

Identification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2-JNK signalling in breast cancer., Puvirajesinghe TM,Bertucci F,Jain A,Scerbo P,Belotti E,Audebert S,Sebbagh M,Lopez M,Brech A,Finetti P,Charafe-Jauffret E,Chaffanet M,Castellano R,Restouin A,Marchetto S,Collette Y,Gonçalvès A,Macara I,Birnbaum D,Kodjabachian L,Johansen T,Borg JP, Nat Commun. January 12, 2016; 7:2041-1723.

Immunosuppressive evidence of Tityus serrulatus toxins Ts6 and Ts15: insights of a novel K(+) channel pattern in T cells., Pucca MB,Bertolini TB,Cerni FA,Bordon KC,Peigneur S,Tytgat J,Bonato VL,Arantes EC, Immunology. February 1, 2016; 147(2):1365-2567.

A novel mutant Na + /HCO3 - cotransporter NBCe1 in a case of compound-heterozygous inheritance of proximal renal tubular acidosis., Myers EJ,Yuan L,Felmlee MA,Lin YY,Jiang Y,Pei Y,Wang O,Li M,Xing XP,Marshall A,Xia WB,Parker MD, J Physiol. November 1, 2016; 594(21):0022-3751.

A Retinoic Acid-Hedgehog Cascade Coordinates Mesoderm-Inducing Signals and Endoderm Competence during Lung Specification., Rankin SA,Rankin SA,Han L,McCracken KW,Kenny AP,Anglin CT,Grigg EA,Crawford CM,Wells JM,Shannon JM,Zorn AM, Cell Rep. June 28, 2016; 16(1):2211-1247.

ROMK expression remains unaltered in a mouse model of familial hyperkalemic hypertension caused by the CUL3Δ403-459 mutation., Murthy M,Kurz T,O'Shaughnessy KM, Physiol Rep. July 1, 2016; 4(13):2051-817X.

Functional aspects of early brain development are preserved in tuberous sclerosis complex (TSC) epileptogenic lesions., Ruffolo G,Iyer A,Cifelli P,Roseti C,Mühlebner A,van Scheppingen J,Scholl T,Hainfellner JA,Feucht M,Krsek P,Zamecnik J,Jansen FE,Spliet WG,Limatola C,Aronica E,Palma E, Neurobiol Dis. November 1, 2016; 95:1095-953X.

Potentiators exert distinct effects on human, murine, and Xenopus CFTR., Cui G,Khazanov N,Stauffer BB,Infield DT,Imhoff BR,Senderowitz H,McCarty NA, Am J Physiol Lung Cell Mol Physiol. August 1, 2016; 311(2):1522-1504.

Fragile X mental retardation protein knockdown in the developing Xenopus tadpole optic tectum results in enhanced feedforward inhibition and behavioral deficits., Truszkowski TL,James EJ,Hasan M,Wishard TJ,Liu Z,Pratt KG,Cline HT,Aizenman CD, Neural Dev. August 8, 2016; 11(1):1749-8104.

De novo and inherited mutations in the X-linked gene CLCN4 are associated with syndromic intellectual disability and behavior and seizure disorders in males and females., Palmer EE,Stuhlmann T,Weinert S,Haan E,Van Esch H,Holvoet M,Boyle J,Leffler M,Raynaud M,Moraine C,van Bokhoven H,Kleefstra T,Kahrizi K,Najmabadi H,Ropers HH,Delgado MR,Sirsi D,Golla S,Sommer A,Pietryga MP,Chung WK,Wynn J,Rohena L,Bernardo E,Hamlin D,Faux BM,Grange DK,Manwaring L,Tolmie J,Joss S,Cobben JM,Duijkers FAM,Goehringer JM,Challman TD,Hennig F,Fischer U,Grimme A,Suckow V,Musante L,Nicholl J,Shaw M,Lodh SP,Niu Z,Rosenfeld JA,Stankiewicz P,Jentsch TJ,Gecz J,Field M,Kalscheuer VM, Mol Psychiatry. February 1, 2018; 23(2):1476-5578.

Gain-of-function defects of astrocytic Kir4.1 channels in children with autism spectrum disorders and epilepsy., Sicca F,Ambrosini E,Marchese M,Sforna L,Servettini I,Valvo G,Brignone MS,Lanciotti A,Moro F,Grottesi A,Catacuzzeno L,Baldini S,Hasan S,D'Adamo MC,Franciolini F,Molinari P,Santorelli FM,Pessia M, Sci Rep. September 28, 2016; 6:2045-2322.

Functional and molecular identification of a TASK-1 potassium channel regulating chloride secretion through CFTR channels in the shark rectal gland: implications for cystic fibrosis., Telles CJ,Decker SE,Motley WW,Peters AW,Mehr AP,Frizzell RA,Forrest JN, Am J Physiol Cell Physiol. December 1, 2016; 311(6):1522-1563.

Functional Recovery of AQP2 Recessive Mutations Through Hetero-Oligomerization with Wild-Type Counterpart., El Tarazi A,Lussier Y,Da Cal S,Bissonnette P,Bichet DG, Sci Rep. September 19, 2016; 6:2045-2322.

Determining the optimal developmental stages of Xenopus laevis for initiating exposures to chemicals for sensitively detecting their feminizing effects on gonadal differentiation., Li YY,Chen J,Qin ZF, Aquat Toxicol. October 1, 2016; 179:1879-1514.

no privacy, a Xenopus tropicalis mutant, is a model of human Hermansky-Pudlak Syndrome and allows visualization of internal organogenesis during tadpole development., Nakayama T,Nakajima K,Cox A,Fisher M,Fisher M,Howell M,Fish MB,Yaoita Y,Grainger RM, Dev Biol. June 15, 2017; 426(2):1095-564X.

Congenital Heart Disease Genetics Uncovers Context-Dependent Organization and Function of Nucleoporins at Cilia., Del Viso F,Huang F,Myers J,Chalfant M,Zhang Y,Zhang Y,Reza N,Bewersdorf J,Lusk CP,Khokha MK, Dev Cell. September 12, 2016; 38(5):1878-1551.

The Enigma of the Dichotomic Pressure Response of GluN1-4a/b Splice Variants of NMDA Receptor: Experimental and Statistical Analyses., Bliznyuk A,Gradwohl G,Hollmann M,Grossman Y, Front Mol Neurosci. February 15, 2016; 9:1662-5099.

Mutation Linked to Autosomal Dominant Nocturnal Frontal Lobe Epilepsy Reduces Low-Sensitivity α4β2, and Increases α5α4β2, Nicotinic Receptor Surface Expression., Nichols WA,Henderson BJ,Marotta CB,Yu CY,Richards C,Dougherty DA,Lester HA,Cohen BN, PLoS One. January 1, 2016; 11(6):1932-6203.

A Splice Variant of Bardet-Biedl Syndrome 5 (BBS5) Protein that Is Selectively Expressed in Retina., Bolch SN,Dugger DR,Chong T,McDowell JH,Smith WC, PLoS One. January 1, 2016; 11(2):1932-6203.

CRISPR/Cas9 mediated knockout of rb1 and rbl1 leads to rapid and penetrant retinoblastoma development in Xenopus tropicalis., Naert T,Colpaert R,Van Nieuwenhuysen T,Dimitrakopoulou D,Leoen J,Haustraete J,Boel A,Steyaert W,Lepez T,Deforce D,Willaert A,Creytens D,Vleminckx K,Vleminckx K, Sci Rep. October 14, 2016; 6:2045-2322.

Expression of ribosomopathy genes during Xenopus tropicalis embryogenesis., Robson A,Owens ND,Baserga SJ,Khokha MK,Griffin JN, BMC Dev Biol. October 26, 2016; 16(1):1471-213X.

Novel KCNQ3 Mutation in a Large Family with Benign Familial Neonatal Epilepsy: A Rare Cause of Neonatal Seizures., Maljevic S,Vejzovic S,Bernhard MK,Bertsche A,Weise S,Döcker M,Lerche H,Lemke JR,Merkenschlager A,Syrbe S, Mol Syndromol. September 1, 2016; 7(4):1661-8769.

Copy number variation as a genetic basis for heterotaxy and heterotaxy-spectrum congenital heart defects., Cowan JR,Tariq M,Shaw C,Rao M,Belmont JW,Lalani SR,Smolarek TA,Ware SM, Philos Trans R Soc Lond B Biol Sci. December 19, 2016; 371(1710):1471-2970.

From cytoskeletal dynamics to organ asymmetry: a nonlinear, regulative pathway underlies left-right patterning., McDowell G,Rajadurai S,Levin M, Philos Trans R Soc Lond B Biol Sci. December 19, 2016; 371(1710):1471-2970.

Functional assessment of SLC4A11, an integral membrane protein mutated in corneal dystrophies., Loganathan SK,Schneider HP,Morgan PE,Deitmer JW,Casey JR, Am J Physiol Cell Physiol. November 1, 2016; 311(5):1522-1563.

Sox9 function in craniofacial development and disease., Lee YH,Lee YH,Saint-Jeannet JP, Genesis. April 1, 2011; 49(4):1526-968X.

Functional and clinical characterization of KCNJ2 mutations associated with LQT7 (Andersen syndrome)., Tristani-Firouzi M,Jensen JL,Donaldson MR,Sansone V,Meola G,Hahn A,Bendahhou S,Kwiecinski H,Fidzianska A,Plaster N,Fu YH,Ptacek LJ,Tawil R, J Clin Invest. August 1, 2002; 110(3):1558-8238.

Pa2G4 is a novel Six1 co-factor that is required for neural crest and otic development., Neilson KM,Abbruzzesse G,Kenyon K,Bartolo V,Krohn P,Alfandari D,Alfandari D,Moody SA, Dev Biol. January 15, 2017; 421(2):1095-564X.

An Epha4/Sipa1l3/Wnt pathway regulates eye development and lens maturation., Rothe M,Kanwal N,Dietmann P,Seigfried FA,Hempel A,Schütz D,Reim D,Engels R,Linnemann A,Schmeisser MJ,Bockmann J,Kühl M,Boeckers TM,Kühl SJ, Development. January 15, 2017; 144(2):1477-9129.

Association between Single-Nucleotide Polymorphisms of the hOGG1,NEIL1,APEX1, FEN1,LIG1, and LIG3 Genes and Alzheimer's Disease Risk., Kwiatkowski D,Czarny P,Toma M,Korycinska A,Sowinska K,Galecki P,Bachurska A,Bielecka-Kowalska A,Szemraj J,Maes M,Sliwinski T, Neuropsychobiology. January 1, 2016; 73(2):1423-0224.

Heterozygous Pathogenic Variant in DACT1 Causes an Autosomal-Dominant Syndrome with Features Overlapping Townes-Brocks Syndrome., Webb BD,Metikala S,Wheeler PG,Sherpa MD,Houten SM,Horb ME,Schadt EE, Hum Mutat. April 1, 2017; 38(4):1098-1004.

Mutations in GABRB3: From febrile seizures to epileptic encephalopathies., Møller RS,Wuttke TV,Helbig I,Marini C,Johannesen KM,Brilstra EH,Vaher U,Borggraefe I,Talvik I,Talvik T,Kluger G,Francois LL,Lesca G,de Bellescize J,Blichfeldt S,Chatron N,Holert N,Jacobs J,Swinkels M,Betzler C,Syrbe S,Nikanorova M,Myers CT,Larsen LH,Vejzovic S,Pendziwiat M,von Spiczak S,Hopkins S,Dubbs H,Mang Y,Mukhin K,Holthausen H,van Gassen KL,Dahl HA,Tommerup N,Mefford HC,Rubboli G,Guerrini R,Lemke JR,Lerche H,Muhle H,Maljevic S, Neurology. January 31, 2017; 88(5):1526-632X.

TALENs and CRISPR/Cas9 fuel genetically engineered clinically relevant Xenopus tropicalis tumor models., Naert T,Van Nieuwenhuysen T,Vleminckx K,Vleminckx K, Genesis. January 1, 2017; 55(1-2):1526-968X.

Opposing Effects of Valproic Acid Treatment Mediated by Histone Deacetylase Inhibitor Activity in Four Transgenic X. laevis Models of Retinitis Pigmentosa., Vent-Schmidt RYJ,Wen RH,Zong Z,Chiu CN,Tam BM,May CG,Moritz OL, J Neurosci. January 25, 2017; 37(4):1529-2401.

Xenopus, an ideal model organism to study laterality in conjoined twins., Tisler M,Schweickert A,Blum M, Genesis. January 1, 2017; 55(1-2):1526-968X.

Using Xenopus to understand human disease and developmental disorders., Sater AK,Moody SA, Genesis. January 1, 2017; 55(1-2):1526-968X.

Leftward Flow Determines Laterality in Conjoined Twins., Tisler M,Thumberger T,Schneider I,Schweickert A,Blum M, Curr Biol. February 20, 2017; 27(4):0960-9822.

Modeling human craniofacial disorders in Xenopus., Dubey A,Saint-Jeannet JP, Curr Pathobiol Rep. March 1, 2017; 5(1):2167-485X.

A Mutation in the G-Protein Gene GNB2 Causes Familial Sinus Node and Atrioventricular Conduction Dysfunction., Stallmeyer B,Kuß J,Kotthoff S,Zumhagen S,Vowinkel K,Rinné S,Matschke LA,Friedrich C,Schulze-Bahr E,Rust S,Seebohm G,Decher N,Schulze-Bahr E, Circ Res. May 12, 2017; 120(10):1524-4571.

Analysis of Craniocardiac Malformations in Xenopus using Optical Coherence Tomography., Deniz E,Jonas S,Hooper M,N Griffin J,Choma MA,Khokha MK, Sci Rep. February 14, 2017; 7:2045-2322.

Toolbox in a tadpole: Xenopus for kidney research., Getwan M,Lienkamp SS, Cell Tissue Res. July 1, 2017; 369(1):1432-0878.

Clinical and Genetic Spectrum of Bartter Syndrome Type 3., Seys E,Andrini O,Keck M,Mansour-Hendili L,Courand PY,Simian C,Deschenes G,Kwon T,Bertholet-Thomas A,Bobrie G,Borde JS,Bourdat-Michel G,Decramer S,Cailliez M,Krug P,Cozette P,Delbet JD,Dubourg L,Chaveau D,Fila M,Jourde-Chiche N,Knebelmann B,Lavocat MP,Lemoine S,Djeddi D,Llanas B,Louillet F,Merieau E,Mileva M,Mota-Vieira L,Mousson C,Nobili F,Novo R,Roussey-Kesler G,Vrillon I,Walsh SB,Teulon J,Blanchard A,Vargas-Poussou R, J Am Soc Nephrol. August 1, 2017; 28(8):1533-3450.

A Dominant Mutation in Nuclear Receptor Interacting Protein 1 Causes Urinary Tract Malformations via Dysregulation of Retinoic Acid Signaling., Vivante A,Mann N,Yonath H,Weiss AC,Getwan M,Kaminski MM,Bohnenpoll T,Teyssier C,Chen J,Shril S,van der Ven AT,Ityel H,Schmidt JM,Widmeier E,Bauer SB,Sanna-Cherchi S,Gharavi AG,Lu W,Magen D,Shukrun R,Lifton RP,Tasic V,Stanescu HC,Cavaillès V,Kleta R,Anikster Y,Dekel B,Kispert A,Lienkamp SS,Hildebrandt F, J Am Soc Nephrol. August 1, 2017; 28(8):1533-3450.

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A Conserved Role of the Unconventional Myosin 1d in Laterality Determination., Tingler M,Kurz S,Maerker M,Ott T,Fuhl F,Schweickert A,LeBlanc-Straceski JM,Noselli S,Blum M, Curr Biol. March 5, 2018; 28(5):0960-9822.

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Targeted deletion of the aquaglyceroporin AQP9 is protective in a mouse model of Parkinson's disease., Stahl K,Rahmani S,Prydz A,Skauli N,MacAulay N,Mylonakou MN,Torp R,Skare Ø,Berg T,Leergaard TB,Paulsen RE,Ottersen OP,Amiry-Moghaddam M, PLoS One. January 1, 2018; 13(3):1932-6203.

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The Effects of 4-Hydroxybenzoic Acid Identified from Bamboo (Dendrocalamus asper) Shoots on Kv1.4 Channel., Zhang J,Mohamad FH,Wong JH,Mohamad H,Ismail AH,Mohamed Yusoff AA,Osman H,Wong KT,Idris Z,Abdullah JM, Malays J Med Sci. February 1, 2018; 25(1):1394-195X.

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Identification of a cono-RFamide from the venom of Conus textile that targets ASIC3 and enhances muscle pain., Reimers C,Lee CH,Lee CH,Lee CH,Kalbacher H,Tian Y,Hung CH,Schmidt A,Prokop L,Kauferstein S,Mebs D,Chen CC,Gründer S, Proc Natl Acad Sci U S A. April 25, 2017; 114(17):1091-6490.

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Nucleotide receptor P2RY4 is required for head formation via induction and maintenance of head organizer in Xenopus laevis., Harata A,Hirakawa M,Sakuma T,Yamamoto T,Hashimoto C, Dev Growth Differ. February 1, 2019; 61(2):1440-169X.

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Katanin-like protein Katnal2 is required for ciliogenesis and brain development in Xenopus embryos., Willsey HR,Walentek P,Exner CRT,Xu Y,Xu Y,Lane AB,Harland RM,Heald R,Santama N, Dev Biol. October 15, 2018; 442(2):1095-564X.

The nucleoside-diphosphate kinase NME3 associates with nephronophthisis proteins and is required for ciliary function during renal development., Hoff S,Epting D,Falk N,Schroda S,Braun DA,Halbritter J,Hildebrandt F,Kramer-Zucker A,Bergmann C,Walz G,Lienkamp SS, J Biol Chem. September 28, 2018; 293(39):1083-351X.

Overexpression of TPX2 is associated with progression and prognosis of prostate cancer., Zou J,Huang RY,Jiang FN,Chen DX,Wang C,Wang C,Wang C,Han ZD,Liang YX,Zhong WD, Oncol Lett. September 1, 2018; 16(3):1792-1074.

Id genes are essential for early heart formation., Cunningham TJ,Yu MS,McKeithan WL,Spiering S,Carrette F,Huang CT,Bushway PJ,Tierney M,Albini S,Giacca M,Mano M,Puri PL,Sacco A,Ruiz-Lozano P,Riou JF,Umbhauer M,Duester G,Mercola M,Colas AR, Genes Dev. July 1, 2017; 31(13):1549-5477.

CRISPR/Cas9 F0 Screening of Congenital Heart Disease Genes in Xenopus tropicalis., Deniz E,Mis EK,Lane M,Khokha MK, Methods Mol Biol. January 1, 2018; 1865:1940-6029.

Cancer Models in Xenopus tropicalis by CRISPR/Cas9 Mediated Knockout of Tumor Suppressors., Naert T,Vleminckx K,Vleminckx K, Methods Mol Biol. January 1, 2018; 1865:1940-6029.

Lack of response to quinidine in KCNT1-related neonatal epilepsy., Numis AL,Nair U,Datta AN,Sands TT,Oldham MS,Patel A,Li M,Gazina E,Petrou S,Cilio MR, Epilepsia. October 1, 2018; 59(10):1528-1167.

Mutations in multiple components of the nuclear pore complex cause nephrotic syndrome., Braun DA,Lovric S,Schapiro D,Schneider R,Marquez J,Asif M,Hussain MS,Daga A,Widmeier E,Rao J,Ashraf S,Tan W,Lusk CP,Kolb A,Jobst-Schwan T,Schmidt JM,Hoogstraten CA,Eddy K,Kitzler TM,Shril S,Moawia A,Schrage K,Khayyat AIA,Lawson JA,Gee HY,Warejko JK,Hermle T,Majmundar AJ,Hugo H,Budde B,Motameny S,Altmüller J,Noegel AA,Fathy HM,Gale DP,Waseem SS,Khan A,Kerecuk L,Hashmi S,Mohebbi N,Ettenger R,Serdaroğlu E,Alhasan KA,Hashem M,Goncalves S,Ariceta G,Ubetagoyena M,Antonin W,Baig SM,Alkuraya FS,Shen Q,Xu H,Antignac C,Lifton RP,Mane S,Nürnberg P,Khokha MK,Hildebrandt F, J Clin Invest. October 1, 2018; 128(10):1558-8238.

CRISPR/Cas9 disease models in zebrafish and Xenopus: The genetic renaissance of fish and frogs., Naert T,Vleminckx K,Vleminckx K, Drug Discov Today Technol. August 1, 2018; 28:1740-6749.

A review of interventions against fetal alcohol spectrum disorder targeting oxidative stress., Zhang Y,Zhang Y,Wang H,Li Y,Peng Y, Int J Dev Neurosci. December 1, 2018; 71:0736-5748.

WDR5 Stabilizes Actin Architecture to Promote Multiciliated Cell Formation., Kulkarni SS,Griffin JN,Date PP,Liem KF,Khokha MK, Dev Cell. September 10, 2018; 46(5):1878-1551.

S4-S5 linker movement during activation and inactivation in voltage-gated K+ channels., Kalstrup T,Blunck R, Proc Natl Acad Sci U S A. July 17, 2018; 115(29):1091-6490.

Inactivation of KCNQ1 potassium channels reveals dynamic coupling between voltage sensing and pore opening., Hou P,Eldstrom J,Shi J,Zhong L,McFarland K,Gao Y,Fedida D,Cui J, Nat Commun. November 23, 2017; 8(1):2041-1723.

Par3 interacts with Prickle3 to generate apical PCP complexes in the vertebrate neural plate., Chuykin I,Ossipova O,Sokol SY, Elife. September 26, 2018; 7:2050-084X.

TPX2 level correlates with cholangiocarcinoma cell proliferation, apoptosis, and EMT., Zou Z,Zheng B,Li J,Lv X,Zhang H,Yu F,Kong L,Li Y,Yu M,Fang L,Liang B, Biomed Pharmacother. November 1, 2018; 107:0753-3322.

Paracetamol-induced liver injury modelled in Xenopus laevis embryos., Saide K,Sherwood V,Wheeler GN, Toxicol Lett. March 1, 2019; 302:1879-3169.

The evolutionary conserved FOXJ1 target gene Fam183b is essential for motile cilia in Xenopus but dispensable for ciliary function in mice., Beckers A,Ott T,Schuster-Gossler K,Boldt K,Alten L,Ueffing M,Blum M,Gossler A, Sci Rep. October 2, 2018; 8(1):2045-2322.

Functional analysis of a triplet deletion in the gene encoding the sodium glucose transporter 3, a potential risk factor for ADHD., Schäfer N,Friedrich M,Jørgensen ME,Kollert S,Koepsell H,Wischmeyer E,Lesch KP,Geiger D,Döring F, PLoS One. October 4, 2018; 13(10):1932-6203.

ITGBL1 modulates integrin activity to promote cartilage formation and protect against arthritis., Song EK,Jeon J,Jang DG,Kim HE,Sim HJ,Kwon KY,Medina-Ruiz S,Jang HJ,Lee AR,Rho JG,Lee HS,Lee HS,Kim SJ,Park CY,Myung K,Kim W,Kwon T,Yang S,Park TJ, Sci Transl Med. October 10, 2018; 10(462):1946-6242.

5-Diphosphoinositol pentakisphosphate (5-IP7) regulates phosphate release from acidocalcisomes and yeast vacuoles., Potapenko E,Cordeiro CD,Huang G,Storey M,Wittwer C,Dutta AK,Jessen HJ,Starai VJ,Docampo R, J Biol Chem. December 7, 2018; 293(49):1083-351X.

A novel GABAergic dysfunction in human Dravet syndrome., Ruffolo G,Cifelli P,Roseti C,Thom M,van Vliet EA,Limatola C,Aronica E,Palma E, Epilepsia. November 1, 2018; 59(11):1528-1167.

Retinal tissue preparation for high-resolution live imaging of photoreceptors expressing multiple transgenes., Haeri M,Zhuo X,Haeri M,Knox BE, MethodsX. March 16, 2018; 5:2215-0161.

Evolutionarily conserved Tbx5-Wnt2/2b pathway orchestrates cardiopulmonary development., Steimle JD,Rankin SA,Rankin SA,Slagle CE,Bekeny J,Rydeen AB,Chan SS,Kweon J,Yang XH,Ikegami K,Nadadur RD,Rowton M,Hoffmann AD,Lazarevic S,Thomas W,Boyle Anderson EAT,Horb ME,Luna-Zurita L,Ho RK,Kyba M,Jensen B,Zorn AM,Conlon FL,Moskowitz IP, Proc Natl Acad Sci U S A. November 6, 2018; 115(45):1091-6490.

De novo pathogenic variants in neuronal differentiation factor 2 (NEUROD2) cause a form of early infantile epileptic encephalopathy., Sega AG,Mis EK,Lindstrom K,Mercimek-Andrews S,Ji W,Cho MT,Juusola J,Konstantino M,Jeffries L,Khokha MK,Lakhani SA, J Med Genet. February 1, 2019; 56(2):1468-6244.

WDR5 regulates left-right patterning via chromatin-dependent and -independent functions., Kulkarni SS,Khokha MK, Development. November 28, 2018; 145(23):1477-9129.

A novel ATP1A2 mutation in a patient with hypokalaemic periodic paralysis and CNS symptoms., Sampedro Castañeda M,Zanoteli E,Scalco RS,Scaramuzzi V,Marques Caldas V,Conti Reed U,da Silva AMS,O'Callaghan B,Phadke R,Bugiardini E,Sud R,McCall S,Hanna MG,Poulsen H,Männikkö R,Matthews E, Brain. December 1, 2018; 141(12):1460-2156.

DNp73-induced degradation of tyrosinase links depigmentation with EMT-driven melanoma progression., Fürst K,Steder M,Logotheti S,Angerilli A,Spitschak A,Marquardt S,Schumacher T,Engelmann D,Herchenröder O,Rupp RAW,Pützer BM, Cancer Lett. February 1, 2019; 442:0304-3835.

A novel autosomal recessive GJB2-associated disorder: Ichthyosis follicularis, bilateral severe sensorineural hearing loss, and punctate palmoplantar keratoderma., Youssefian L,Vahidnezhad H,Saeidian AH,Mahmoudi H,Karamzadeh R,Kariminejad A,Huang J,Li L,Jannace TF,Fortina P,Zeinali S,White TW,Uitto J, Hum Mutat. February 1, 2019; 40(2):1098-1004.

Acetaldehyde inhibits retinoic acid biosynthesis to mediate alcohol teratogenicity., Shabtai Y,Bendelac L,Jubran H,Hirschberg J,Fainsod A, Sci Rep. January 10, 2018; 8(1):2045-2322.

The low binding affinity of D-serine at the ionotropic glutamate receptor GluD2 can be attributed to the hinge region., Tapken D,Steffensen TB,Leth R,Kristensen LB,Gerbola A,Gajhede M,Jørgensen FS,Olsen L,Kastrup JS, Sci Rep. April 7, 2017; 7:2045-2322.

Extended Cleavage Specificity of Human Neutrophil Elastase, Human Proteinase 3, and Their Distant Ortholog Clawed Frog PR3-Three Elastases With Similar Primary but Different Extended Specificities and Stability., Fu Z,Thorpe M,Akula S,Chahal G,Hellman LT, Front Immunol. September 12, 2018; 9:1664-3224.

Targeting TPX2 suppresses proliferation and promotes apoptosis via repression of the PI3k/AKT/P21 signaling pathway and activation of p53 pathway in breast cancer., Chen M,Zhang H,Zhang G,Zhong A,Ma Q,Kai J,Tong Y,Xie S,Wang Y,Zheng H,Guo L,Lu R, Biochem Biophys Res Commun. December 9, 2018; 507(1-4):1090-2104.

Mutations in Kinesin family member 6 reveal specific role in ependymal cell ciliogenesis and human neurological development., Konjikusic MJ,Yeetong P,Boswell CW,Lee C,Lee C,Lee C,Roberson EC,Ittiwut R,Suphapeetiporn K,Ciruna B,Gurnett CA,Wallingford JB,Shotelersuk V,Gray RS, PLoS Genet. November 6, 2018; 14(11):1553-7404.

A Xenopus tadpole alternative model to study innate-like T cell-mediated anti-mycobacterial immunity., Hyoe RK,Robert J, Dev Comp Immunol. March 1, 2019; 92:1879-0089.

Hydrophobic pore gates regulate ion permeation in polycystic kidney disease 2 and 2L1 channels., Zheng W,Yang X,Hu R,Cai R,Hofmann L,Wang Z,Hu Q,Liu X,Bulkley D,Yu Y,Tang J,Flockerzi V,Cao Y,Cao Y,Cao E,Chen XZ, Nat Commun. June 13, 2018; 9(1):2041-1723.

HCN2 Rescues brain defects by enforcing endogenous voltage pre-patterns., Pai VP,Pietak A,Willocq V,Ye B,Shi NQ,Levin M, Nat Commun. March 8, 2018; 9(1):2041-1723.

Candidate Heterotaxy Gene FGFR4 Is Essential for Patterning of the Left-Right Organizer in Xenopus., Sempou E,Lakhani OA,Amalraj S,Khokha MK, Front Physiol. January 1, 2018; 9:1664-042X.

A liquid-like organelle at the root of motile ciliopathy., Huizar RL,Lee C,Lee C,Lee C,Boulgakov AA,Horani A,Tu F,Marcotte EM,Brody SL,Wallingford JB, Elife. December 18, 2018; 7:2050-084X.

Leukemia inhibitory factor signaling in Xenopus embryo: Insights from gain of function analysis and dominant negative mutant of the receptor., Jalvy S,Veschambre P,Fédou S,Rezvani HR,Thézé N,Thiébaud P, Dev Biol. March 15, 2019; 447(2):1095-564X.

Retinoic acid signaling reduction recapitulates the effects of alcohol on embryo size., Shukrun N,Shabtai Y,Pillemer G,Fainsod A, Genesis. July 1, 2019; 57(7-8):1526-968X.

De Novo SOX4 Variants Cause a Neurodevelopmental Disease Associated with Mild Dysmorphism., Zawerton A,Yao B,Yeager JP,Pippucci T,Haseeb A,Smith JD,Wischmann L,Kühl SJ,Dean JCS,Pilz DT,Holder SE,McNeill A,Graziano C,Lefebvre V, Am J Hum Genet. February 7, 2019; 104(2):1537-6605.

CFTR supports cell death through ROS-dependent activation of TMEM16F (anoctamin 6)., Simões F,Ousingsawat J,Wanitchakool P,Fonseca A,Cabrita I,Benedetto R,Schreiber R,Kunzelmann K, Pflugers Arch. February 1, 2018; 470(2):1432-2013.

Anillin regulates epithelial cell mechanics by structuring the medial-apical actomyosin network., Arnold TR,Shawky JH,Stephenson RE,Dinshaw KM,Higashi T,Huq F,Davidson LA,Davidson LA,Miller AL,Miller AL, Elife. January 31, 2019; 8:2050-084X.

The clinical significance and prognostic value of Xenopus kinesin-like protein 2 expressions in human tumors: A systematic review and meta-analysis., Yang W,Wan H,Shan R,Wen W,Li J,Luo D,Wan RH, J Cell Physiol. September 1, 2019; 234(9):1097-4652.

Xenopus tropicalis: Joining the Armada in the Fight Against Blood Cancer., Dimitrakopoulou D,Tulkens D,Van Vlierberghe P,Vleminckx K,Vleminckx K, Front Physiol. January 1, 2019; 10:1664-042X.

Myasthenic congenital myopathy from recessive mutations at a single residue in NaV1.4., Elia N,Palmio J,Castañeda MS,Shieh PB,Quinonez M,Suominen T,Hanna MG,Männikkö R,Udd B,Cannon SC, Neurology. March 26, 2019; 92(13):1526-632X.

Electrophysiological Changes During Early Steps of Retinitis Pigmentosa., Bocchero U,Tam BM,Chiu CN,Torre V,Moritz OL, Invest Ophthalmol Vis Sci. March 1, 2019; 60(4):1552-5783.

FoxN3 is necessary for the development of the interatrial septum, the ventricular trabeculae and the muscles at the head/trunk interface in the African clawed frog, Xenopus laevis (Lissamphibia: Anura: Pipidae)., Naumann B,Schmidt J,Olsson L, Dev Dyn. May 1, 2019; 248(5):1058-8388.

The Frog Xenopus as a Model to Study Joubert Syndrome: The Case of a Human Patient With Compound Heterozygous Variants in PIBF1., Ott T,Kaufmann L,Granzow M,Hinderhofer K,Bartram CR,Theiß S,Seitz A,Paramasivam N,Schulz A,Moog U,Blum M,Evers CM, Front Physiol. January 1, 2019; 10:1664-042X.

Structural basis of HEAT-kleisin interactions in the human condensin I subcomplex., Hara K,Kinoshita K,Migita T,Murakami K,Shimizu K,Takeuchi K,Hirano T,Hashimoto H, EMBO Rep. May 1, 2019; 20(5):1469-3178.

Prdm12 Directs Nociceptive Sensory Neuron Development by Regulating the Expression of the NGF Receptor TrkA., Desiderio S,Vermeiren S,Van Campenhout C,Kricha S,Malki E,Richts S,Fletcher EV,Vanwelden T,Schmidt BZ,Henningfeld KA,Pieler T,Woods CG,Nagy V,Verfaillie C,Bellefroid EJ, Cell Rep. March 26, 2019; 26(13):2211-1247.

A de novo Ser111Thr variant in aquaporin-4 in a patient with intellectual disability, transient signs of brain ischemia, transient cardiac hypertrophy, and progressive gait disturbance., Berland S,Toft-Bertelsen TL,Aukrust I,Byska J,Vaudel M,Bindoff LA,MacAulay N,Houge G, Cold Spring Harb Mol Case Stud. February 1, 2018; 4(1):2373-2873.

Latrophilin2 is involved in neural crest cell migration and placode patterning in Xenopus laevis., Yokote N,Suzuki-Kosaka MY,Michiue T,Hara T,Tanegashima K, Int J Dev Biol. January 1, 2019; 63(1-2):1696-3547.

Desmoplakin is required for epidermal integrity and morphogenesis in the Xenopus laevis embryo., Bharathan NK,Dickinson AJG, Dev Biol. June 15, 2019; 450(2):1095-564X.

ANK2 functionally interacts with KCNH2 aggravating long QT syndrome in a double mutation carrier., Gessner G,Runge S,Koenen M,Heinemann SH,Koenen M,Haas J,Meder B,Thomas D,Katus HA,Schweizer PA, Biochem Biophys Res Commun. May 14, 2019; 512(4):1090-2104.

N-glycosylation-dependent regulation of hK2P17.1 currents., Wiedmann F,Schlund D,Voigt N,Ratte A,Kraft M,Katus HA,Schmidt C, Mol Biol Cell. June 1, 2019; 30(12):1939-4586.

Modeling congenital kidney diseases in Xenopus laevis., Blackburn ATM,Miller RK, Dis Model Mech. April 9, 2019; 12(4):1754-8411.

Loss of function of Kmt2d, a gene mutated in Kabuki syndrome, affects heart development in Xenopus laevis., Schwenty-Lara J,Nürnberger A,Borchers A, Dev Dyn. June 1, 2019; 248(6):1058-8388.

ECT2 associated to PRICKLE1 are poor-prognosis markers in triple-negative breast cancer., Daulat AM,Finetti P,Revinski D,Silveira Wagner M,Camoin L,Audebert S,Birnbaum D,Kodjabachian L,Borg JP,Bertucci F, Br J Cancer. April 1, 2019; 120(9):0007-0920.

Urokinase-type plasminogen activator (uPA) is not essential for epithelial sodium channel (ENaC)-mediated sodium retention in experimental nephrotic syndrome., Bohnert BN,Daiminger S,Wörn M,Sure F,Staudner T,Ilyaskin AV,Batbouta F,Janessa A,Schneider JC,Essigke D,Kanse S,Haerteis S,Korbmacher C,Artunc F, Acta Physiol (Oxf). December 1, 2019; 227(4):1748-1716.

Visualizing flow in an intact CSF network using optical coherence tomography: implications for human congenital hydrocephalus., Date P,Ackermann P,Furey C,Fink IB,Jonas S,Khokha MK,Kahle KT,Deniz E, Sci Rep. April 17, 2019; 9(1):2045-2322.

Activation of the calcium sensing receptor attenuates TRPV6-dependent intestinal calcium absorption., Lee JJ,Lee JJ,Liu X,O'Neill D,Beggs MR,Weissgerber P,Flockerzi V,Chen XZ,Dimke H,Alexander RT, JCI Insight. April 23, 2019; 5:2379-3708.

A YWHAZ Variant Associated With Cardiofaciocutaneous Syndrome Activates the RAF-ERK Pathway., Popov IK,Hiatt SM,Whalen S,Keren B,Ruivenkamp C,van Haeringen A,Chen MJ,Cooper GM,Korf BR,Chang C, Front Physiol. January 1, 2019; 10:1664-042X.

Wolf-Hirschhorn Syndrome-Associated Genes Are Enriched in Motile Neural Crest Cells and Affect Craniofacial Development in Xenopus laevis., Mills A,Bearce E,Cella R,Kim SW,Selig M,Lee S,Lowery LA, Front Physiol. January 1, 2019; 10:1664-042X.

Aβ1-42 triggers the generation of a retrograde signaling complex from sentinel mRNAs in axons., Walker CA,Randolph LK,Matute C,Alberdi E,Baleriola J,Hengst U, EMBO Rep. July 1, 2018; 19(7):1469-3178.

Antinociceptive effects of new pyrazoles compounds mediated by the ASIC-1α channel, TRPV-1 and μMOR receptors., Florentino IF,Silva DPB,Cardoso CS,Menegatti R,de Carvalho FS,Lião LM,Pinto PM,Peigneur S,Costa EA,Tytgat J, Biomed Pharmacother. July 1, 2019; 115:0753-3322.

ANP-stimulated Na+ secretion in the collecting duct prevents Na+ retention in the renal adaptation to acid load., Cheval L,Bakouh N,Walter C,Tembely D,Morla L,Escher G,Vogt B,Crambert G,Planelles G,Doucet A, Am J Physiol Renal Physiol. August 1, 2019; 317(2):1522-1466.

Injection of mRNA isolated from trophozoites of Giardia intestinalis induces expression of three types of chloride currents in Xenopus laevis oocytes., Ponce A,Ogazon Del Toro A,Jimenez L,Eligio-Garcia L,Jimenez-Cardoso E, Physiol Rep. June 1, 2019; 7(11):2051-817X.

Rare Diseases of Neurodevelopment: Maintain the Mystery or Use a Dazzling Tool for Investigation? The Case of Rett Syndrome., Ruffolo G,Cifelli P,Miranda-Lourenço C,De Felice E,Limatola C,Sebastião AM,Diógenes MJ,Aronica E,Palma E, Neuroscience. July 15, 2020; 439:1873-7544.

Dishevelled Paralogs in Vertebrate Development: Redundant or Distinct?, Gentzel M,Schambony A, Front Cell Dev Biol. May 26, 2017; 5:2296-634X.

Rabies virus modifies host behaviour through a snake-toxin like region of its glycoprotein that inhibits neurotransmitter receptors in the CNS., Hueffer K,Khatri S,Rideout S,Harris MB,Papke RL,Stokes C,Schulte MK, Sci Rep. October 9, 2017; 7(1):2045-2322.

DYRK1A-related intellectual disability: a syndrome associated with congenital anomalies of the kidney and urinary tract., Blackburn ATM,Bekheirnia N,Uma VC,Corkins ME,Xu Y,Xu Y,Rosenfeld JA,Bainbridge MN,Yang Y,Yang Y,Liu P,Madan-Khetarpal S,Delgado MR,Hudgins L,Krantz I,Rodriguez-Buritica D,Wheeler PG,Al-Gazali L,Mohamed Saeed Mohamed Al Shamsi A,Gomez-Ospina N,Chao HT,Mirzaa GM,Scheuerle AE,Kukolich MK,Scaglia F,Eng C,Willsey HR,Braun MC,Lamb DJ,Miller RK,Bekheirnia MR, Genet Med. December 1, 2019; 21(12):1530-0366.

Functional characterization of SMN evolution in mouse models of SMA., Osman EY,Bolding MR,Villalón E,Kaifer KA,Lorson ZC,Tisdale S,Hao Y,Conant GC,Pires JC,Pellizzoni L,Lorson CL, Sci Rep. July 1, 2019; 9(1):2045-2322.

Concomitant exposure to benzo[a]pyrene and triclosan at environmentally relevant concentrations induces metabolic syndrome with multigenerational consequences in Silurana (Xenopus) tropicalis., Usal M,Regnault C,Veyrenc S,Couturier K,Batandier C,Bulteau AL,Lejon D,Combourieu B,Lafond T,Raveton M,Reynaud S, Sci Total Environ. November 1, 2019; 689:1879-1026.

Kidney-specific WNK1 isoform (KS-WNK1) is a potent activator of WNK4 and NCC., Argaiz ER,Chavez-Canales M,Ostrosky-Frid M,Rodríguez-Gama A,Vázquez N,Gonzalez-Rodriguez X,Garcia-Valdes J,Hadchouel J,Ellison D,Gamba G, Am J Physiol Renal Physiol. September 1, 2018; 315(3):1522-1466.

The Many Faces of Xenopus: Xenopus laevis as a Model System to Study Wolf-Hirschhorn Syndrome., Lasser M,Pratt B,Monahan C,Kim SW,Lowery LA, Front Physiol. January 1, 2019; 10:1664-042X.

Molecular characterization of an aquaporin-2 mutation causing a severe form of nephrogenic diabetes insipidus., Saglar Ozer E,Moeller HB,Karaduman T,Fenton RA,Mergen H, Cell Mol Life Sci. March 1, 2020; 77(5):1420-9071.

The VAMP-associated protein VAPB is required for cardiac and neuronal pacemaker channel function., Silbernagel N,Walecki M,Schäfer MK,Kessler M,Zobeiri M,Rinné S,Kiper AK,Komadowski MA,Vowinkel KS,Wemhöner K,Fortmüller L,Schewe M,Dolga AM,Scekic-Zahirovic J,Matschke LA,Culmsee C,Baukrowitz T,Monassier L,Ullrich ND,Dupuis L,Just S,Budde T,Fabritz L,Decher N, FASEB J. November 1, 2018; 32(11):1530-6860.

NA3 glycan: a potential therapy for retinal pigment epithelial deficiency., Chintalapudi SR,Wang X,Wang X,Shi Y,Shi Y,Kocak M,Palamoor M,Davis RN,Hollingsworth TJ,Jablonski MM, FEBS J. December 1, 2019; 286(24):1742-4658.

Sorafenib Activity and Disposition in Liver Cancer Does Not Depend on Organic Cation Transporter 1., Chen M,Neul C,Schaeffeler E,Frisch F,Winter S,Schwab M,Koepsell H,Hu S,Laufer S,Baker SD,Sparreboom A,Nies AT, Clin Pharmacol Ther. January 1, 2020; 107(1):1532-6535.

Alkylglycerol monooxygenase, a heterotaxy candidate gene, regulates left-right patterning via Wnt signaling., Duncan AR,González DP,Del Viso F,Robson A,Khokha MK,Griffin JN, Dev Biol. December 1, 2019; 456(1):1095-564X.

Comparative Embryonic Spatio-Temporal Expression Profile Map of the Xenopus P2X Receptor Family., Blanchard C,Boué-Grabot E,Massé K, Front Cell Neurosci. January 1, 2019; 13:1662-5102.

Migraine-Associated TRESK Mutations Increase Neuronal Excitability through Alternative Translation Initiation and Inhibition of TREK., Royal P,Andres-Bilbe A,Ávalos Prado P,Verkest C,Wdziekonski B,Schaub S,Baron A,Lesage F,Gasull X,Levitz J,Sandoz G, Neuron. January 16, 2019; 101(2):0896-6273.

Xenopus: Driving the Discovery of Novel Genes in Patient Disease and Their Underlying Pathological Mechanisms Relevant for Organogenesis., Hwang WY,Marquez J,Khokha MK, Front Physiol. January 1, 2019; 10:1664-042X.

De novo variants in SLC12A6 cause sporadic early-onset progressive sensorimotor neuropathy., Park J,Flores BR,Scherer K,Kuepper H,Rossi M,Rupprich K,Rautenberg M,Deininger N,Weichselbaum A,Grimm A,Sturm M,Grasshoff U,Delpire E,Haack TB, J Med Genet. April 1, 2020; 57(4):1468-6244.

Understanding cornea homeostasis and wound healing using a novel model of stem cell deficiency in Xenopus., Adil MT,Simons CM,Sonam S,Henry JJ, Exp Eye Res. October 1, 2019; 187:0014-4835.

Divergent roles of the Wnt/PCP Formin Daam1 in renal ciliogenesis., Corkins ME,Krneta-Stankic V,Kloc M,McCrea PD,Gladden AB,Miller RK, PLoS One. January 1, 2019; 14(8):1932-6203.

Functional characterization of Kv11.1 (hERG) potassium channels split in the voltage-sensing domain., de la Peña P,Domínguez P,Barros F, Pflugers Arch. July 1, 2018; 470(7):1432-2013.

The molecular determinants of R-roscovitine block of hERG channels., Cernuda B,Fernandes CT,Allam SM,Orzillo M,Suppa G,Chia Chang Z,Athanasopoulos D,Buraei Z, PLoS One. September 3, 2019; 14(9):1932-6203.

Evaluation of mutant muscle Ca2+ channel properties using two different expression systems., Allard B, J Gen Physiol. July 2, 2018; 150(7):1540-7748.

Conservation and divergence of protein pathways in the vertebrate heart., Federspiel JD,Tandon P,Wilczewski CM,Wasson L,Herring LE,Venkatesh SS,Cristea IM,Conlon FL, PLoS Biol. September 6, 2019; 17(9):1545-7885.

Characteristics of in Vivo Model Systems for Ovarian Cancer Studies., Tudrej P,Kujawa KA,Cortez AJ,Lisowska KM, Diagnostics (Basel). September 14, 2019; 9(3):2075-4418.

ΔN-Tp63 Mediates Wnt/β-Catenin-Induced Inhibition of Differentiation in Basal Stem Cells of Mucociliary Epithelia., Haas M,Gómez Vázquez JL,Sun DI,Tran HT,Brislinger M,Tasca A,Shomroni O,Vleminckx K,Vleminckx K,Walentek P, Cell Rep. September 24, 2019; 28(13):2211-1247.

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SLC20A1 Is Involved in Urinary Tract and Urorectal Development., Rieke JM,Zhang R,Braun D,Yilmaz Ö,Japp AS,Lopes FM,Pleschka M,Hilger AC,Schneider S,Newman WG,Beaman GM,Nordenskjöld A,Ebert AK,Promm M,Rösch WH,Stein R,Hirsch K,Schäfer FM,Schmiedeke E,Boemers TM,Lacher M,Kluth D,Gosemann JH,Anderberg M,Barker G,Holmdahl G,Läckgren G,Keene D,Cervellione RM,Giorgio E,Di Grazia M,Feitz WFJ,Marcelis CLM,Van Rooij IALM,Bökenkamp A,Beckers GMA,Keegan CE,Sharma A,Dakal TC,Wittler L,Grote P,Zwink N,Jenetzky E,Brusco A,Thiele H,Ludwig M,Schweizer U,Woolf AS,Odermatt B,Reutter H, Front Cell Dev Biol. January 1, 2020; 8:2296-634X.

Characterization of AN317, a novel selective agonist of α6β2-containing nicotinic acetylcholine receptors., Sandager-Nielsen K,Ahring PK,Klein J,van Hout M,Thaneshwaran S,Dos Santos AB,Jacobsen TA,Amrutkar DV,Peters D,Jensen AA,Kohlmeier KA,Christophersen P,Dyhring T, Biochem Pharmacol. April 1, 2020; 174:1873-2968.

Tetrapeptide Ac-HAEE-NH2 Protects α4β2 nAChR from Inhibition by Aβ., Barykin EP,Garifulina AI,Tolstova AP,Anashkina AA,Adzhubei AA,Mezentsev YV,Shelukhina IV,Kozin SA,Tsetlin VI,Makarov AA, Int J Mol Sci. August 29, 2020; 21(17):1422-0067.

A Collision Coupling Model Governs the Activation of Neuronal GIRK1/2 Channels by Muscarinic-2 Receptors., Berlin S,Artzy E,Handklo-Jamal R,Kahanovitch U,Parnas H,Dascal N,Yakubovich D, Front Pharmacol. April 7, 2020; 11:1663-9812.

Using an aquatic model, Xenopus laevis, to uncover the role of chromodomain 1 in craniofacial disorders., Wyatt BH,Raymond TO,Lansdon LA,Darbro BW,Murray JC,Manak JR,Dickinson AJG, Genesis. February 1, 2021; 59(1-2):1526-968X.

Acute consequences of a unilateral VIIIth nerve transection on vestibulo-ocular and optokinetic reflexes in Xenopus laevis tadpoles., Soupiadou P,Gordy C,Forsthofer M,Sanchez-Gonzalez R,Straka H, J Neurol. December 1, 2020; 267(Suppl 1):1432-1459.

Establishing embryonic territories in the context of Wnt signaling., Velloso I,Maia LA,Amado NG,Reis AH,He X,Abreu JG, Int J Dev Biol. January 1, 2021; 65(4-5-6):1696-3547.

Role of epigenetics and miRNAs in orofacial clefts., Garland MA,Sun B,Zhang S,Reynolds K,Ji Y,Zhou CJ, Birth Defects Res. November 1, 2020; 112(19):2472-1727.

TMEM79/MATTRIN defines a pathway for Frizzled regulation and is required for Xenopus embryogenesis., Chen M,Amado N,Tan J,Reis A,Ge M,Abreu JG,He X, Elife. September 14, 2020; 9:2050-084X.

Isoform-Selective KCNA1 Potassium Channel Openers Built from Glycine., Manville RW,Abbott GW, J Pharmacol Exp Ther. June 1, 2020; 373(3):1521-0103.

Disruption of Cav1.2-mediated signaling is a pathway for ketamine-induced pathology., Chen H,Vandorpe DH,Xie X,Alper SL,Zeidel ML,Yu W, Nat Commun. August 28, 2020; 11(1):2041-1723.

Amiodarone bioconcentration and suppression of metamorphosis in Xenopus., Sanoh S,Hanada H,Kashiwagi K,Mori T,Goto-Inoue N,Suzuki KT,Mori J,Nakamura N,Yamamoto T,Kitamura S,Kotake Y,Sugihara K,Ohta S,Kashiwagi A, Aquat Toxicol. November 1, 2020; 228:1879-1514.

Structural determinants of TRPV4 inhibition and identification of new antagonists with antiviral activity., Doñate-Macian P,Duarte Y,Rubio-Moscardo F,Pérez-Vilaró G,Canan J,Díez J,González-Nilo F,Valverde MA, Br J Pharmacol. July 1, 2022; 179(14):1476-5381.

A nonsense variant in Rap Guanine Nucleotide Exchange Factor 5 (RAPGEF5) is associated with equine familial isolated hypoparathyroidism in Thoroughbred foals., Rivas VN,Magdesian KG,Fagan S,Slovis NM,Luethy D,Javsicas LH,Caserto BG,Miller AD,Dahlgren AR,Peterson J,Hales EN,Peng S,Watson KD,Khokha MK,Finno CJ, PLoS Genet. September 28, 2020; 16(9):1553-7404.

Alignment of Alzheimer's disease amyloid β-peptide and klotho., Lehrer S,Rheinstein PH, World Acad Sci J. January 1, 2020; 2(6):2632-2919.

The Stemness Gene Mex3A Is a Key Regulator of Neuroblast Proliferation During Neurogenesis., Naef V,De Sarlo M,Testa G,Corsinovi D,Azzarelli R,Borello U,Ori M, Front Cell Dev Biol. January 1, 2020; 8:2296-634X.

A Common Kinetic Property of Mutations Linked to Episodic Ataxia Type 1 Studied in the Shaker Kv Channel., Zhao J,Petitjean D,Haddad GA,Batulan Z,Blunck R, Int J Mol Sci. October 14, 2020; 21(20):1422-0067.

Nucleoporin NUP205 plays a critical role in cilia and congenital disease., Marquez J,Bhattacharya D,Lusk CP,Khokha MK, Dev Biol. January 1, 2021; 469:1095-564X.

S-nitrosylation of connexin43 hemichannels elicits cardiac stress-induced arrhythmias in Duchenne muscular dystrophy mice., Lillo MA,Himelman E,Shirokova N,Xie LH,Fraidenraich D,Contreras JE, JCI Insight. December 19, 2019; 4(24):2379-3708.

Dual Screen for Efficacy and Toxicity Identifies HDAC Inhibitor with Distinctive Activity Spectrum for BAP1-Mutant Uveal Melanoma., Kuznetsoff JN,Owens DA,Lopez A,Rodriguez DA,Chee NT,Kurtenbach S,Bilbao D,Roberts ER,Volmar CH,Wahlestedt C,Brothers SP,Harbour JW, Mol Cancer Res. February 1, 2021; 19(2):1557-3125.

Disease-associated HCN4 V759I variant is not sufficient to impair cardiac pacemaking., Erlenhardt N,Kletke O,Wohlfarth F,Komadowski MA,Clasen L,Makimoto H,Rinné S,Kelm M,Jungen C,Decher N,Meyer C,Klöcker N, Pflugers Arch. December 1, 2020; 472(12):1432-2013.

Structural bioinformatics predicts that the Retinitis Pigmentosa-28 protein of unknown function FAM161A is a homologue of the microtubule nucleation factor Tpx2., Levine TP, F1000Res. January 1, 2020; 9:2046-1402.

Potential reproductive toxicity of multi-walled carbon nanotubes and their chronic exposure effects on the growth and development of Xenopus tropicalis., Zhao J,Luo W,Xu Y,Xu Y,Ling J,Deng L, Sci Total Environ. April 20, 2021; 766:1879-1026.

Stapled and Xenopus Glucagon-Like Peptide 1 (GLP-1)-Based Dual GLP-1/Gastrin Receptor Agonists with Improved Metabolic Benefits in Rodent Models of Obesity and Diabetes., Chen X,Fu J,Zhou F,Yang Q,Wang J,Feng H,Jiang W,Jin L,Tang X,Jiang N,Yin J,Han J, J Med Chem. November 12, 2020; 63(21):1520-4804.

The anticonvulsant zonisamide positively modulates recombinant and native glycine receptors at clinically relevant concentrations., Devenish SO,Winters BL,Anderson LL,Arnold JC,McGregor IS,Vaughan CW,Chebib M,Absalom NL, Neuropharmacology. January 1, 2021; 182:1873-7064.

Voltage-Dependent Dopamine Potency at D1-Like Dopamine Receptors., Ågren R,Sahlholm K, Front Pharmacol. April 7, 2020; 11:1663-9812.

Simple binding of protein kinase A prior to phosphorylation allows CFTR anion channels to be opened by nucleotides., Mihályi C,Iordanov I,Töröcsik B,Csanády L, Proc Natl Acad Sci U S A. September 1, 2020; 117(35):1091-6490.

Allosteric regulation of mammalian Na+/I- symporter activity by perchlorate., Llorente-Esteban A,Manville RW,Reyna-Neyra A,Abbott GW,Amzel LM,Carrasco N, Nat Struct Mol Biol. June 1, 2020; 27(6):1545-9985.

Periodic albinism of a widely used albino mutant of Xenopus laevis caused by deletion of two exons in the Hermansky-Pudlak syndrome type 4 gene., Fukuzawa T, Genes Cells. January 1, 2021; 26(1):1356-9597.

Experimental Approaches to Identify Selective Picomolar Inhibitors for Carbonic Anhydrase IX., Kazokaitė-Adomaitienė J,Becker HM,Smirnovienė J,Dubois LJ,Matulis D, Curr Med Chem. January 1, 2021; 28(17):1875-533X.

Increased Dissociation of Adamantanamines in Influenza A M2 S31N with Partial Block by Rimantadine., McGuire KL,Hill JT,Busath DD, Biophys J. November 3, 2020; 119(9):1542-0086.

R-spondins are BMP receptor antagonists in Xenopus early embryonic development., Lee H,Lee H,Seidl C,Sun R,Glinka A,Niehrs C, Nat Commun. November 4, 2020; 11(1):2041-1723.

Functional Integrity of Synapses in the Central Nervous System of Cognitively Intact Individuals with High Alzheimer's Disease Neuropathology Is Associated with Absence of Synaptic Tau Oligomers., Singh A,Allen D,Fracassi A,Tumurbaatar B,Natarajan C,Scaduto P,Woltjer R,Kayed R,Limon A,Krishnan B,Taglialatela G, J Alzheimers Dis. January 1, 2020; 78(4):1875-8908.

Building neuromuscular junctions in vitro., Barbeau S,Tahraoui-Bories J,Legay C,Martinat C, Development. November 16, 2020; 147(22):1477-9129.

DAAM2 Variants Cause Nephrotic Syndrome via Actin Dysregulation., Schneider R,Deutsch K,Hoeprich GJ,Marquez J,Hermle T,Braun DA,Seltzsam S,Kitzler TM,Mao Y,Buerger F,Majmundar AJ,Onuchic-Whitford AC,Kolvenbach CM,Schierbaum L,Schneider S,Halawi AA,Nakayama M,Mann N,Connaughton DM,Klämbt V,Wagner M,Riedhammer KM,Renders L,Katsura Y,Thumkeo D,Soliman NA,Mane S,Lifton RP,Shril S,Khokha MK,Hoefele J,Goode BL,Hildebrandt F, Am J Hum Genet. December 3, 2020; 107(6):1537-6605.

Functional partitioning of a liquid-like organelle during assembly of axonemal dyneins., Lee C,Lee C,Lee C,Cox RM,Papoulas O,Horani A,Drew K,Devitt CC,Brody SL,Marcotte EM,Wallingford JB, Elife. December 2, 2020; 9:2050-084X.

A System for Assessing Dual Action Modulators of Glycine Transporters and Glycine Receptors., Sheipouri D,Gallagher CI,Shimmon S,Rawling T,Vandenberg RJ, Biomolecules. November 30, 2020; 10(12):2218-273X.

Clinical and molecular characterization of the R751L-CFTR mutation., Haq IJ,Althaus M,Gardner AI,Yeoh HY,Joshi U,Saint-Criq V,Verdon B,Townshend J,O'Brien C,Ben-Hamida M,Thomas M,Bourke S,van der Sluijs P,Braakman I,Ward C,Gray MA,Brodlie M, Am J Physiol Lung Cell Mol Physiol. February 1, 2021; 320(2):1522-1504.

Overexpression of TPX2 predicts poor clinical outcome and is associated with immune infiltration in hepatic cell cancer., Zhu H,Liu J,Feng J,Zhang Q,Bian T,Li X,Sun H,Zhang J,Liu Y, Medicine (Baltimore). December 4, 2020; 99(49):1536-5964.

Characterization of the GABRB2-Associated Neurodevelopmental Disorders., El Achkar CM,Harrer M,Smith L,Kelly M,Iqbal S,Maljevic S,Niturad CE,Vissers LELM,Poduri A,Yang E,Lal D,Lerche H,Møller RS,Olson HE, Ann Neurol. March 1, 2021; 89(3):1531-8249.

A Functional Comparison of Homopentameric Nicotinic Acetylcholine Receptors (ACR-16) Receptors From Necator americanus and Ancylostoma ceylanicum., Kaji MD,Geary TG,Beech RN, Front Mol Neurosci. January 1, 2020; 13:1662-5099.

The RNA helicase DDX3 induces neural crest by promoting AKT activity., Perfetto M,Xu X,Lu C,Shi Y,Shi Y,Yousaf N,Li J,Yien YY,Wei S, Development. January 19, 2021; 148(2):1477-9129.

Functional modulation of the human voltage-gated sodium channel NaV1.8 by auxiliary β subunits., Nevin ST,Lawrence N,Nicke A,Lewis RJ,Adams DJ, Channels (Austin). December 1, 2021; 15(1):1933-6969.

VX-770-mediated potentiation of numerous human CFTR disease mutants is influenced by phosphorylation level., Cui G,Stauffer BB,Imhoff BR,Rab A,Hong JS,Sorscher EJ,McCarty NA, Sci Rep. September 17, 2019; 9(1):2045-2322.

Beneficial actions of the [A14K] analog of the frog skin peptide PGLa-AM1 in mice with obesity and degenerative diabetes: A mechanistic study., Musale V,Moffett RC,Conlon JM,Flatt PR,Abdel-Wahab YH, Peptides. February 1, 2021; 136:1873-5169.

Familial neonatal seizures caused by the Kv7.3 selectivity filter mutation T313I., Maghera J,Li J,Lamothe SM,Braun M,Appendino JP,Au PYB,Kurata HT, Epilepsia Open. December 1, 2020; 5(4):2470-9239.

MiR-9 and the Midbrain-Hindbrain Boundary: A Showcase for the Limited Functional Conservation and Regulatory Complexity of MicroRNAs., Alwin Prem Anand A,Alvarez-Bolado G,Wizenmann A, Front Cell Dev Biol. January 1, 2020; 8:2296-634X.

Differential Coassembly of α1-GABAARs Associated with Epileptic Encephalopathy., Hannan S,Affandi AHB,Minere M,Jones C,Goh P,Warnes G,Popp B,Trollmann R,Nizetic D,Smart TG, J Neurosci. July 15, 2020; 40(29):1529-2401.

Using Xenopus to analyze neurocristopathies like Kabuki syndrome., Schwenty-Lara J,Pauli S,Borchers A, Genesis. February 1, 2021; 59(1-2):1526-968X.

Xenopus leads the way: Frogs as a pioneering model to understand the human brain., Exner CRT,Willsey HR, Genesis. February 1, 2021; 59(1-2):1526-968X.

Editorial: Xenopus Models of Organogenesis and Disease., Griffin JN,Liu KJ,Liu KJ,Sempou E, Front Physiol. January 1, 2020; 11:1664-042X.

Phosphorylation of a chronic pain mutation in the voltage-gated sodium channel Nav1.7 increases voltage sensitivity., Kerth CM,Hautvast P,Körner J,Lampert A,Meents JE, J Biol Chem. January 1, 2021; 296:1083-351X.

Xenopus epidermal and endodermal epithelia as models for mucociliary epithelial evolution, disease, and metaplasia., Walentek P, Genesis. February 1, 2021; 59(1-2):1526-968X.

Distinct roles for prominin-1 and photoreceptor cadherin in outer segment disc morphogenesis in CRISPR-altered X. laevis., Carr BJ,Stanar P,Moritz OL, J Cell Sci. January 11, 2021; 134(1):1477-9137.

Developing Tadpole Xenopus laevis as a Comparative Animal Model to Study Mycobacterium abscessus Pathogenicity., Lopez A,Shoen C,Cynamon M,Dimitrakopoulou D,Paiola M,Pavelka MS,Robert J, Int J Mol Sci. January 15, 2021; 22(2):1422-0067.

Rab11fip5 regulates telencephalon development via ephrinB1 recycling., Yoon J,Garo J,Lee M,Sun J,Hwang YS,Daar IO, Development. February 2, 2021; 148(3):1477-9129.

TRESK and TREK-2 two-pore-domain potassium channel subunits form functional heterodimers in primary somatosensory neurons., Lengyel M,Czirják G,Jacobson DA,Enyedi P, J Biol Chem. August 28, 2020; 295(35):1083-351X.

Neural tube closure requires the endocytic receptor Lrp2 and its functional interaction with intracellular scaffolds., Kowalczyk I,Lee C,Lee C,Lee C,Schuster E,Hoeren J,Trivigno V,Riedel L,Görne J,Wallingford JB,Hammes A,Feistel K, Development. January 26, 2021; 148(2):1477-9129.

Molecular Mechanism of Autosomal Recessive Long QT-Syndrome 1 without Deafness., Oertli A,Rinné S,Moss R,Kääb S,Seemann G,Beckmann BM,Decher N, Int J Mol Sci. January 23, 2021; 22(3):1422-0067.

Parallel in vivo analysis of large-effect autism genes implicates cortical neurogenesis and estrogen in risk and resilience., Willsey HR,Exner CRT,Xu Y,Xu Y,Everitt A,Sun N,Wang B,Dea J,Schmunk G,Zaltsman Y,Teerikorpi N,Kim A,Anderson AS,Shin D,Seyler M,Nowakowski TJ,Harland RM,Willsey AJ,State MW, Neuron. March 3, 2021; 109(5):0896-6273.

Aquatic models of human ciliary diseases., Corkins ME,Krneta-Stankic V,Kloc M,Miller RK, Genesis. February 1, 2021; 59(1-2):1526-968X.

Quantifying the dose-dependent impact of intracellular amyloid beta in a mathematical model of calcium regulation in xenopus oocyte., Minicucci J,Alfond M,Demuro A,Gerberry D,Latulippe J, PLoS One. January 28, 2021; 16(1):1932-6203.

Use of Xenopus laevis cell-free extracts to study BRCA2 role in chromosome alignment., El Dika M, DNA Repair (Amst). April 1, 2021; 100:1568-7856.

Geoffroea decorticans fruit extracts inhibit the wnt/β-catenin pathway, a therapeutic target in cancer., Somaini GC,Aybar MJ,Aybar MJ,Vera NR,Tríbulo C, Biochem Biophys Res Commun. March 26, 2021; 546:1090-2104.

Xenopus to the rescue: A model to validate and characterize candidate ciliopathy genes., Rao VG,Kulkarni SS, Genesis. February 1, 2021; 59(1-2):1526-968X.

Retinol binding protein 1 affects Xenopus anterior neural development via all-trans retinoic acid signaling., Flach H,Basten T,Schreiner C,Dietmann P,Greco S,Nies L,Roßmanith N,Walter S,Kühl M,Kühl SJ, Dev Dyn. August 1, 2021; 250(8):1058-8388.

Mutations in PRDM15 Are a Novel Cause of Galloway-Mowat Syndrome., Mann N,Mzoughi S,Schneider R,Kühl SJ,Schanze D,Klämbt V,Lovric S,Mao Y,Shi S,Tan W,Kühl M,Onuchic-Whitford AC,Treimer E,Kitzler TM,Kause F,Schumann S,Nakayama M,Buerger F,Shril S,van der Ven AT,Majmundar AJ,Holton KM,Kolb A,Braun DA,Rao J,Jobst-Schwan T,Mildenberger E,Lennert T,Kuechler A,Wieczorek D,Gross O,Ermisch-Omran B,Werberger A,Skalej M,Janecke AR,Soliman NA,Mane SM,Lifton RP,Kadlec J,Guccione E,Schmeisser MJ,Zenker M,Hildebrandt F, J Am Soc Nephrol. March 1, 2021; 32(3):1533-3450.

Synthesis and biological evaluation of benzhydryl-based antiplasmodial agents possessing Plasmodium falciparum chloroquine resistance transporter (PfCRT) inhibitory activity., Relitti N,Federico S,Pozzetti L,Butini S,Lamponi S,Taramelli D,D'Alessandro S,Martin RE,Shafik SH,Summers RL,Babij SK,Habluetzel A,Tapanelli S,Caldelari R,Gemma S,Campiani G, Eur J Med Chem. April 5, 2021; 215:1768-3254.

Biallelic variants in COPB1 cause a novel, severe intellectual disability syndrome with cataracts and variable microcephaly., Macken WL,Godwin A,Wheway G,Stals K,Nazlamova L,Ellard S,Alfares A,Aloraini T,AlSubaie L,Alfadhel M,Alajaji S,Wai HA,Self J,Douglas AGL,Kao AP,Guille M,Baralle D, Genome Med. February 25, 2021; 13(1):1756-994X.

Sleep-related hypermotor epilepsy associated mutations uncover important kinetic roles of α4β2- nicotinic acetylcholine receptor intracellular structures., Weltzin MM,George AA,Lukas RJ,Whiteaker P, PLoS One. March 3, 2021; 16(3):1932-6203.

Functional and Structural Characterization of ClC-1 and Nav1.4 Channels Resulting from CLCN1 and SCN4A Mutations Identified Alone and Coexisting in Myotonic Patients., Brenes O,Barbieri R,Vásquez M,Vindas-Smith R,Roig J,Romero A,Valle GD,Bermúdez-Guzmán L,Bertelli S,Pusch M,Morales F, Cells. February 11, 2021; 10(2):2073-4409.

Differential Regulation of Human Serotonin Receptor Type 3A by Chanoclavine and Ergonovine., Eom S,Jung W,Lee J,Lee J,Yeom HD,Lee S,Kim C,Park HD,Lee JH,Lee JH, Molecules. February 24, 2021; 26(5):1420-3049.

BRCA1-BARD1 regulates transcription through BRD4 in Xenopus nucleoplasmic extract., Barrows JK,Fullbright G,Long DT, Nucleic Acids Res. April 6, 2021; 49(6):1362-4962.

High nuclear TPX2 expression correlates with TP53 mutation and poor clinical behavior in a large breast cancer cohort, but is not an independent predictor of chromosomal instability., Matson DR,Denu RA,Zasadil LM,Burkard ME,Weaver BA,Flynn C,Stukenberg PT, BMC Cancer. February 23, 2021; 21(1):1471-2407.

Thyroid Disrupting Chemicals in Mixture Perturb Thymocyte Differentiation in Xenopus laevis Tadpoles., McGuire CC,Lawrence BP,Robert J, Toxicol Sci. May 27, 2021; 181(2):1096-0929.

Mcrs1 interacts with Six1 to influence early craniofacial and otic development., Neilson KM,Keer S,Bousquet N,Macrorie O,Majumdar HD,Kenyon KL,Alfandari D,Alfandari D,Moody SA, Dev Biol. November 1, 2020; 467(1-2):1095-564X.

Compound Heterozygous KCNQ1 Mutations Causing Recessive Romano-Ward Syndrome: Functional Characterization by Mutant Co-expression., González-Garrido A,Domínguez-Pérez M,Jacobo-Albavera L,López-Ramírez O,Guevara-Chávez JG,Zepeda-García O,Iturralde P,Carnevale A,Villarreal-Molina T, Front Cardiovasc Med. February 22, 2021; 8:2297-055X.

RNA demethylation by FTO stabilizes the FOXJ1 mRNA for proper motile ciliogenesis., Kim H,Lee YS,Lee YS,Kim SM,Jang S,Choi H,Lee JW,Lee JW,Kim TD,Kim VN, Dev Cell. April 19, 2021; 56(8):1878-1551.

Cation leak underlies neuronal excitability in an HCN1 developmental and epileptic encephalopathy., Bleakley LE,McKenzie CE,Soh MS,Forster IC,Pinares-Garcia P,Sedo A,Kathirvel A,Churilov L,Jancovski N,Maljevic S,Berkovic SF,Scheffer IE,Petrou S,Santoro B,Reid CA, Brain. August 17, 2021; 144(7):1460-2156.

Functional assessment of the "two-hit" model for neurodevelopmental defects in Drosophila and X. laevis., Pizzo L,Lasser M,Yusuff T,Jensen M,Ingraham P,Huber E,Singh MD,Monahan C,Iyer J,Desai I,Karthikeyan S,Gould DJ,Yennawar S,Weiner AT,Pounraja VK,Krishnan A,Rolls MM,Lowery LA,Girirajan S, PLoS Genet. April 5, 2021; 17(4):1553-7404.

Dissecting the Molecular Determinants of GABAA Receptors Current Rundown, a Hallmark of Refractory Human Epilepsy., Cifelli P,Di Angelantonio S,Alfano V,Morano A,De Felice E,Aronica E,Ruffolo G,Palma E, Brain Sci. March 30, 2021; 11(4):2076-3425.

Bioelectric signaling: Reprogrammable circuits underlying embryogenesis, regeneration, and cancer., Levin M, Cell. April 15, 2021; :1097-4172.

N-terminal region of RecQ4 inhibits non-homologous end joining and chromatin association of the Ku heterodimer in Xenopus egg extracts., Tsuyama T,Fujita K,Sasaki R,Hamanaka S,Sotoyama Y,Ogawa A,Kusuzaki K,Azuma Y,Tada S, Gene. June 30, 2021; 787:1879-0038.

Structure Basis for Shaping the Nse4 Protein by the Nse1 and Nse3 Dimer within the Smc5/6 Complex., Jo A,Li S,Shin JW,Zhao X,Cho Y, J Mol Biol. April 30, 2021; 433(9):1089-8638.

Molecular mechanisms of hearing loss in Nager syndrome., Maharana SK,Saint-Jeannet JP, Dev Biol. August 1, 2021; 476:1095-564X.

HPF1-dependent PARP activation promotes LIG3-XRCC1-mediated backup pathway of Okazaki fragment ligation., Kumamoto S,Nishiyama A,Chiba Y,Miyashita R,Konishi C,Azuma Y,Nakanishi M, Nucleic Acids Res. May 21, 2021; 49(9):1362-4962.

Functional rice with tandemly repeated Cbl-b ubiquitin ligase inhibitory pentapeptide prevents denervation-induced muscle atrophy in vivo., Akama K,Shimajiri Y,Kainou K,Iwasaki R,Nakao R,Nikawa T,Nishikawa A, Biosci Biotechnol Biochem. May 25, 2021; 85(6):1347-6947.

Local Anesthetics Inhibit Transient Receptor Potential Vanilloid Subtype 3 Channel Function in Xenopus Oocytes., Horishita R,Ogata Y,Fukui R,Yamazaki R,Moriwaki K,Ueno S,Yanagihara N,Uezono Y,Yokoyama Y,Minami K,Horishita T, Anesth Analg. June 1, 2021; 132(6):1526-7598.

Chronic Exposure to Two Gestagens Differentially Alters Morphology and Gene Expression in Silurana tropicalis., Thomson P,Pineda M,Yargeau V,Langlois VS, Arch Environ Contam Toxicol. May 1, 2021; 80(4):0090-4341.

Signaling Control of Mucociliary Epithelia: Stem Cells, Cell Fates, and the Plasticity of Cell Identity in Development and Disease., Walentek P, Cells Tissues Organs. January 1, 2022; 211(6):1422-6405.

WIN55,212-2, a Dual Modulator of Cannabinoid Receptors and G Protein-Coupled Inward Rectifier Potassium Channels., An D,Peigneur S,Tytgat J, Biomedicines. April 28, 2021; 9(5):2227-9059.

High-resolution structures of multiple 5-HT3AR-setron complexes reveal a novel mechanism of competitive inhibition., Basak S,Kumar A,Ramsey S,Gibbs E,Kapoor A,Filizola M,Chakrapani S, Elife. October 16, 2020; 9:2050-084X.

Loss-of-function variants in Kv 11.1 cardiac channels as a biomarker for SUDEP., Soh MS,Bagnall RD,Bennett MF,Bleakley LE,Mohamed Syazwan ES,Phillips AM,Chiam MDF,McKenzie CE,Hildebrand M,Crompton D,Bahlo M,Semsarian C,Scheffer IE,Berkovic SF,Reid CA, Ann Clin Transl Neurol. July 1, 2021; 8(7):2328-9503.

Reconstitution of β-adrenergic regulation of CaV1.2: Rad-dependent and Rad-independent protein kinase A mechanisms., Katz M,Subramaniam S,Chomsky-Hecht O,Tsemakhovich V,Flockerzi V,Klussmann E,Hirsch JA,Weiss S,Dascal N, Proc Natl Acad Sci U S A. May 25, 2021; 118(21):1091-6490.

Anaplastic lymphoma kinase (alk), a neuroblastoma associated gene, is expressed in neural crest domains during embryonic development of Xenopus., Moreno MM,Barrell WB,Godwin A,Guille M,Liu KJ,Liu KJ, Gene Expr Patterns. June 1, 2021; 40:1567-133X.

LRR1-mediated replisome disassembly promotes DNA replication by recycling replisome components., Fan Y,Köberlin MS,Ratnayeke N,Liu C,Deshpande M,Gerhardt J,Meyer T, J Cell Biol. August 2, 2021; 220(8):1540-8140.

Early Developmental Exposure to Fluoxetine and Citalopram Results in Different Neurodevelopmental Outcomes., Liu K,Garcia A,Park JJ,Toliver AA,Ramos L,Aizenman CD, Neuroscience. July 15, 2021; 467:1873-7544.

Modeling endoderm development and disease in Xenopus., Edwards NA,Zorn AM, Curr Top Dev Biol. January 1, 2021; 145:1557-8933.

Susceptibility of anurans, lizards, and fish to infection with Dracunculus species larvae and implications for their roles as paratenic hosts., Box EK,Yabsley MJ,Garrett KB,Thompson AT,Wyckoff ST,Cleveland CA, Sci Rep. June 3, 2021; 11(1):2045-2322.

Generation of anisotropic strain dysregulates wild-type cell division at the interface between host and oncogenic tissue., Moruzzi M,Nestor-Bergmann A,Goddard GK,Tarannum N,Brennan K,Woolner S, Curr Biol. August 9, 2021; 31(15):0960-9822.

Altering metabolite distribution at Xenopus cleavage stages affects left-right gene expression asymmetries., Onjiko RM,Nemes P,Moody SA, Genesis. June 1, 2021; 59(5-6):1526-968X.

Protein phosphatase 2A holoenzymes regulate leucine-rich repeat kinase 2 phosphorylation and accumulation., Drouyer M,Bolliger MF,Lobbestael E,Van den Haute C,Emanuele M,Lefebvre R,Sibran W,De Wit T,Leghay C,Mutez E,Dzamko N,Halliday GM,Murayama S,Martoriati A,Cailliau K,Bodart JF,Chartier-Harlin MC,Baekelandt V,Nichols RJ,Taymans JM, Neurobiol Dis. September 1, 2021; 157:1095-953X.

Copepod consumption by amphibians and fish with implications for transmission of Dracunculus species., Box EK,Cleveland CA,Garrett KB,Grunert RK,Hutchins K,Majewska AA,Thompson AT,Wyckoff ST,Ehlers C,Yabsley MJ, Int J Parasitol Parasites Wildl. June 8, 2021; 15:2213-2244.

Fosl1 is vital to heart regeneration upon apex resection in adult Xenopus tropicalis., Wu HY,Zhou YM,Liao ZQ,Zhong JW,Liu YB,Zhao H,Liang CQ,Huang RJ,Park KS,Feng SS,Zheng L,Cai DQ,Qi XF, NPJ Regen Med. June 29, 2021; 6(1):2057-3995.

Tau, XMAP215/Msps and Eb1 co-operate interdependently to regulate microtubule polymerisation and bundle formation in axons., Hahn I,Voelzmann A,Parkin J,Fülle JB,Slater PG,Lowery LA,Sanchez-Soriano N,Prokop A, PLoS Genet. July 1, 2021; 17(7):1553-7404.

Recurrent seizure-related GRIN1 variant: Molecular mechanism and targeted therapy., Xu Y,Xu Y,Song R,Chen W,Strong K,Shrey D,Gedela S,Traynelis SF,Zhang G,Yuan H, Ann Clin Transl Neurol. July 1, 2021; 8(7):2328-9503.

Stapled, Long-Acting Xenopus GLP-1-Based Dual GLP-1/Glucagon Receptor Agonists with Potent Therapeutic Efficacy for Metabolic Disease., Han C,Sun Y,Yang Q,Zhou F,Chen X,Wu L,Sun L,Han J, Mol Pharm. August 2, 2021; 18(8):1543-8392.

Role of matrix metalloproteinase-9 in neurodevelopmental deficits and experience-dependent plasticity in Xenopus laevis., Gore SV,James EJ,Huang LC,Park JJ,Berghella A,Thompson AC,Cline HT,Aizenman CD, Elife. July 20, 2021; 10:2050-084X.

A polycystin-2 protein with modified channel properties leads to an increased diameter of renal tubules and to renal cysts., Grosch M,Brunner K,Ilyaskin AV,Schober M,Staudner T,Schmied D,Stumpp T,Schmidt KN,Madej MG,Pessoa TD,Othmen H,Kubitza M,Osten L,de Vries U,Mair MM,Somlo S,Moser M,Kunzelmann K,Ziegler C,Haerteis S,Korbmacher C,Witzgall R, J Cell Sci. August 15, 2021; 134(16):1477-9137.

Sobp modulates the transcriptional activation of Six1 target genes and is required during craniofacial development., Tavares ALP,Jourdeuil K,Neilson KM,Majumdar HD,Moody SA, Development. September 1, 2021; 148(17):1477-9129.

A convergent molecular network underlying autism and congenital heart disease., Rosenthal SB,Willsey HR,Xu Y,Xu Y,Mei Y,Dea J,Wang S,Curtis C,Sempou E,Khokha MK,Chi NC,Willsey AJ,Fisch KM,Ideker T, Cell Syst. November 17, 2021; 12(11):2405-4720.

Neonatal NaV 1.5 channels: pharmacological distinctiveness of a cancer-related voltage-gated sodium channel splice variant., Fraser SP,Onkal R,Theys M,Bosmans F,Djamgoz MBA, Br J Pharmacol. February 1, 2022; 179(3):1476-5381.

Genetic and Physiological Effects of Insulin on Human Urate Homeostasis., Mandal AK,Leask MP,Estiverne C,Choi HK,Merriman TR,Mount DB, Front Physiol. January 1, 2021; 12:1664-042X.

Influence of Sox protein SUMOylation on neural development and regeneration., Chang KC, Neural Regen Res. March 1, 2022; 17(3):1673-5374.

Conserved role of the urotensin II receptor 4 signalling pathway to control body straightness in a tetrapod., Alejevski F,Leemans M,Gaillard AL,Leistenschneider D,de Flori C,Bougerol M,Le Mével S,Herrel A,Fini JB,Pézeron G,Tostivint H, Open Biol. August 1, 2021; 11(8):2046-2441.

A role for zinc transporter gene SLC39A12 in the nervous system and beyond., Davis DN,Strong MD,Chambers E,Hart MD,Bettaieb A,Clarke SL,Smith BJ,Stoecker BJ,Lucas EA,Lin D,Chowanadisai W, Gene. October 5, 2021; 799:1879-0038.

KCND2 variants associated with global developmental delay differentially impair Kv4.2 channel gating., Zhang Y,Zhang Y,Tachtsidis G,Schob C,Koko M,Hedrich UBS,Lerche H,Lemke JR,van Haeringen A,Ruivenkamp C,Prescott T,Tveten K,Gerstner T,Pruniski B,DiTroia S,VanNoy GE,Rehm HL,McLaughlin H,Bolz HJ,Zechner U,Bryant E,McDonough T,Kindler S,Bähring R, Hum Mol Genet. November 16, 2021; 30(23):1460-2083.

Crosstalk between repair pathways elicits double-strand breaks in alkylated DNA and implications for the action of temozolomide., Fuchs RP,Isogawa A,Paulo JA,Onizuka K,Takahashi T,Amunugama R,Duxin JP,Fujii S, Elife. July 8, 2021; 10:2050-084X.

KCNK18 Biallelic Variants Associated with Intellectual Disability and Neurodevelopmental Disorders Alter TRESK Channel Activity., Pavinato L,Nematian-Ardestani E,Zonta A,De Rubeis S,Buxbaum J,Mancini C,Bruselles A,Tartaglia M,Pessia M,Tucker SJ,D'Adamo MC,Brusco A, Int J Mol Sci. June 4, 2021; 22(11):1422-0067.

Molecular Regulation of Betulinic Acid on α3β4 Nicotinic Acetylcholine Receptors., Lee S,Jung W,Eom S,Yeom HD,Park HD,Lee JH,Lee JH, Molecules. May 1, 2021; 26(9):1420-3049.

Stable desensitization of α7 nicotinic acetylcholine receptors by NS6740 requires interaction with S36 in the orthosteric agonist binding site., Pismataro MC,Horenstein NA,Stokes C,Dallanoce C,Thakur GA,Papke RL, Eur J Pharmacol. August 15, 2021; 905:1879-0712.

Weight of Evidence and Human Relevance Evaluation of the Benfluralin Mode of Action in Rats (Part II): Thyroid carcinogenesis., Strupp C,Quesnot N,Weber-Parmentier C,Richert L,Bomann WH,Singh P, Regul Toxicol Pharmacol. November 1, 2020; 117:1096-0295.

GlyT1 encephalopathy: Characterization of presumably disease causing GlyT1 mutations., Hauf K,Barsch L,Bauer D,Buchert R,Armbruster A,Frauenfeld L,Grasshoff U,Eulenburg V, Neurochem Int. October 1, 2020; 139:1872-9754.

Transport rate of EAAT2 is regulated by amino acid located at the interface between the scaffolding and substrate transport domains., Duffield M,Patel A,Mortensen OV,Schnur D,Gonzalez-Suarez AD,Torres-Salazar D,Fontana ACK, Neurochem Int. October 1, 2020; 139:1872-9754.

Comparative analysis of alternating hemiplegia of childhood and rapid-onset dystonia-parkinsonism ATP1A3 mutations reveals functional deficits, which do not correlate with disease severity., Lazarov E,Hillebrand M,Schröder S,Ternka K,Hofhuis J,Ohlenbusch A,Barrantes-Freer A,Pardo LA,Fruergaard MU,Nissen P,Brockmann K,Gärtner J,Rosewich H, Neurobiol Dis. September 1, 2020; 143:1095-953X.

Mechanosensitive TREK-1 two-pore-domain potassium (K2P) channels in the cardiovascular system., Wiedmann F,Rinné S,Donner B,Decher N,Katus HA,Schmidt C, Prog Biophys Mol Biol. January 1, 2021; 159:1873-1732.

Discovery of Dihydropyrrolo[1,2-a]pyrazin-3(4H)-one-Based Second-Generation GluN2C- and GluN2D-Selective Positive Allosteric Modulators (PAMs) of the N-Methyl-d-Aspartate (NMDA) Receptor., Epplin MP,Mohan A,Harris LD,Zhu Z,Strong KL,Bacsa J,Le P,Menaldino DS,Traynelis SF,Liotta DC, J Med Chem. July 23, 2020; 63(14):1520-4804.

BK channel openers NS1619 and NS11021 reverse hydrogen peroxide-induced membrane potential changes in skeletal muscle., Coskun C,Buyuknacar HS,Cicek F,Gunay I, J Recept Signal Transduct Res. October 1, 2020; 40(5):1532-4281.

Coordinated action of multiple transporters in the acquisition of essential cationic amino acids by the intracellular parasite Toxoplasma gondii., Fairweather SJ,Rajendran E,Blume M,Javed K,Steinhöfel B,McConville MJ,Kirk K,Bröer S,van Dooren GG, PLoS Pathog. August 25, 2021; 17(8):1553-7374.

Function of chromatin modifier Hmgn1 during neural crest and craniofacial development., Ihewulezi C,Saint-Jeannet JP, Genesis. October 1, 2021; 59(10):1526-968X.

Biochemical and developmental effects of thyroid and anti-thyroid drugs on different early life stages of Xenopus laevis., Boran F,Güngördü A, Environ Toxicol Pharmacol. October 1, 2021; 87:1872-7077.

The Molecular Basis of Glucose Galactose Malabsorption in a Large Swedish Pedigree., Lostao MP,Loo DD,Hernell O,Meeuwisse G,Martin MG,Wright EM, Function (Oxf). January 1, 2021; 2(5):2633-8823.

Natural Polyhydroxy Flavonoids, Curcuminoids, and Synthetic Curcumin Analogs as α7 nAChRs Positive Allosteric Modulators., Ximenis M,Mulet J,Sala S,Sala F,Criado M,González-Muñiz R,Pérez de Vega MJ, Int J Mol Sci. January 19, 2021; 22(2):1422-0067.

Modeling human congenital disorders with neural crest developmental defects using patient-derived induced pluripotent stem cells., Okuno H,Okano H, Regen Ther. August 24, 2021; 18:2352-3204.

Single-minded 2 is required for left-right asymmetric stomach morphogenesis., Wyatt BH,Amin NM,Bagley K,Wcisel DJ,Dush MK,Yoder JA,Nascone-Yoder NM, Development. September 1, 2021; 148(17):1477-9129.

Ttc30a affects tubulin modifications in a model for ciliary chondrodysplasia with polycystic kidney disease., Getwan M,Hoppmann A,Schlosser P,Grand K,Song W,Diehl R,Schroda S,Heeg F,Deutsch K,Hildebrandt F,Lausch E,Köttgen A,Lienkamp SS, Proc Natl Acad Sci U S A. September 28, 2021; 118(39):1091-6490.

E-liquids and vanillin flavoring disrupts retinoic acid signaling and causes craniofacial defects in Xenopus embryos., Dickinson AJG,Turner SD,Wahl S,Kennedy AE,Wyatt BH,Howton DA, Dev Biol. January 1, 2022; 481:1095-564X.

Characterization of a Compound Heterozygous SLC2A9 Mutation That Causes Hypouricemia., Yoon J,Cachau R,David VA,Thompson M,Jung W,Jee SH,Daar IO,Winkler CA,Cho SK, Biomedicines. September 6, 2021; 9(9):2227-9059.

The Role of RNA-Binding Proteins in Vertebrate Neural Crest and Craniofacial Development., Forman TE,Dennison BJC,Fantauzzo KA, J Dev Biol. August 27, 2021; 9(3):2221-3759.

Molecular Confirmation of Ranavirus Infection in Amphibians From Chad, Africa., Box EK,Cleveland CA,Subramaniam K,Waltzek TB,Yabsley MJ, Front Vet Sci. September 16, 2021; 8:2297-1769.

Physical basis for distinct basal and mechanically gated activity of the human K+ channel TRAAK., Rietmeijer RA,Sorum B,Li B,Brohawn SG, Neuron. September 15, 2021; 109(18):0896-6273.

Structural comparison of GLUT1 to GLUT3 reveal transport regulation mechanism in sugar porter family., Custódio TF,Paulsen PA,Frain KM,Pedersen BP, Life Sci Alliance. February 3, 2021; 4(4):2575-1077.

Galloway-Mowat syndrome: New insights from bioinformatics and expression during Xenopus embryogenesis., Treimer E,Niedermayer K,Schumann S,Zenker M,Schmeisser MJ,Kühl SJ, Gene Expr Patterns. December 1, 2021; 42:1567-133X.

Teriflunomide Promotes Oligodendroglial 8,9-Unsaturated Sterol Accumulation and CNS Remyelination., Martin E,Aigrot MS,Lamari F,Bachelin C,Lubetzki C,Nait Oumesmar B,Zalc B,Stankoff B, Neurol Neuroimmunol Neuroinflamm. November 1, 2021; 8(6):2332-7812.

Translocation of TMEM175 Lysosomal Potassium Channel to the Plasma Membrane by Dynasore Compounds., Pergel E,Veres I,Csigi GI,Czirják G, Int J Mol Sci. September 29, 2021; 22(19):1422-0067.

Huntingtin CAG expansion impairs germ layer patterning in synthetic human 2D gastruloids through polarity defects., Galgoczi S,Ruzo A,Markopoulos C,Yoney A,Phan-Everson T,Li S,Haremaki T,Metzger JJ,Etoc F,Brivanlou AH, Development. October 1, 2021; 148(19):1477-9129.

Generation of a new six1-null line in Xenopus tropicalis for study of development and congenital disease., Coppenrath K,Tavares ALP,Shaidani NI,Wlizla M,Moody SA,Horb M, Genesis. December 1, 2021; 59(12):1526-968X.

A novel I551F variant of the Na+/HCO3- cotransporter NBCe1-A shows reduced cell surface expression, resulting in diminished transport activity., Yamazaki O,Yamashita M,Li J,Ochiai-Homma F,Yoshida T,Hirahashi J,Furukawa T,Kozuma K,Fujigaki Y,Seki G,Hayashi M,Shibata S, Am J Physiol Renal Physiol. December 1, 2021; 321(6):1522-1466.

Membrane cholesterol regulates TRPV4 function, cytoskeletal expression, and the cellular response to tension., Lakk M,Hoffmann GF,Gorusupudi A,Enyong E,Lin A,Bernstein PS,Toft-Bertelsen T,MacAulay N,Elliott MH,Križaj D, J Lipid Res. January 1, 2021; 62:0022-2275.

Deep learning is widely applicable to phenotyping embryonic development and disease., Naert T,Çiçek Ö,Ogar P,Bürgi M,Shaidani NI,Kaminski MM,Xu Y,Xu Y,Grand K,Vujanovic M,Prata D,Hildebrandt F,Brox T,Ronneberger O,Voigt FF,Helmchen F,Loffing J,Horb ME,Willsey HR,Lienkamp SS, Development. November 1, 2021; 148(21):1477-9129.

Exposure to a mixture of benzo[a]pyrene and triclosan induces multi-and transgenerational metabolic disorders associated with decreased female investment in reproduction in Silurana (Xenopus) tropicalis., Usal M,Veyrenc S,Darracq-Ghitalla-Ciock M,Regnault C,Sroda S,Fini JB,Raveton M,Reynaud S, Environ Pollut. January 1, 2022; 292(Pt B):1873-6424.

Kv3.1 channelopathy: a novel loss-of-function variant and the mechanistic basis of its clinical phenotypes., Li X,Zheng Y,Li S,Nair U,Sun C,Zhao C,Lu J,Zhang VW,Maljevic S,Petrou S,Lin J, Ann Transl Med. September 1, 2021; 9(18):2305-5839.

Molecular mechanisms underlying enhanced hemichannel function of a cataract-associated Cx50 mutant., Tong JJ,Khan U,Haddad BG,Minogue PJ,Beyer EC,Berthoud VM,Reichow SL,Ebihara L, Biophys J. December 21, 2021; 120(24):1542-0086.

Virus-Host Interactions of Enteroviruses and Parvovirus B19 in Myocarditis., Ho HT,Peischard S,Strutz-Seebohm N,Seebohm G, Cell Physiol Biochem. November 18, 2021; 55(6):1421-9778.

CRISPR-SID: Identifying EZH2 as a druggable target for desmoid tumors via in vivo dependency mapping., Naert T,Tulkens D,Van Nieuwenhuysen T,Przybyl J,Demuynck S,van de Rijn M,Al-Jazrawe M,Alman BA,Coucke PJ,De Leeneer K,Vanhove C,Savvides SN,Creytens D,Vleminckx K,Vleminckx K, Proc Natl Acad Sci U S A. November 23, 2021; 118(47):1091-6490.

Structure-based screening combined with computational and biochemical analyses identified the inhibitor targeting the binding of DNA Ligase 1 to UHRF1., Kori S,Shibahashi Y,Ekimoto T,Nishiyama A,Yoshimi S,Yamaguchi K,Nagatoishi S,Ohta M,Tsumoto K,Nakanishi M,Defossez PA,Ikeguchi M,Arita K, Bioorg Med Chem. December 15, 2021; 52:1464-3391.

Evidence for a Genotype-Phenotype Correlation in Patients with Pathogenic GLUT2 (SLC2A2) Variants., Grünert SC,Schumann A,Baronio F,Tsiakas K,Murko S,Spiekerkoetter U,Santer R, Genes (Basel). November 10, 2021; 12(11):2073-4425.

Ion permeation controlled by hydrophobic residues and proton binding in the proton-activated chloride channel., Cai R,Tang J,Chen XZ, iScience. November 1, 2021; 24(12):2589-0042.

Interspecies Differences in Activation of Peroxisome Proliferator-Activated Receptor γ by Pharmaceutical and Environmental Chemicals., Garoche C,Boulahtouf A,Grimaldi M,Chiavarina B,Toporova L,den Broeder MJ,Legler J,Bourguet W,Balaguer P, Environ Sci Technol. December 21, 2021; 55(24):1520-5851.

Frequent SLC12A3 mutations in Chinese Gitelman syndrome patients: structure and function disorder., Jiang L,Peng X,Zhao B,Zhang L,Xu L,Li X,Nie M,Chen L, Endocr Connect. January 27, 2022; 11(1):2049-3614.

Proteolytic activation of the epithelial sodium channel (ENaC) by factor VII activating protease (FSAP) and its relevance for sodium retention in nephrotic mice., Artunc F,Bohnert BN,Schneider JC,Staudner T,Sure F,Ilyaskin AV,Wörn M,Essigke D,Janessa A,Nielsen NV,Birkenfeld AL,Etscheid M,Haerteis S,Korbmacher C,Kanse SM, Pflugers Arch. February 1, 2022; 474(2):1432-2013.

Identification of SCN5a p.C335R Variant in a Large Family with Dilated Cardiomyopathy and Conduction Disease., Sedaghat-Hamedani F,Rebs S,El-Battrawy I,Chasan S,Krause T,Haas J,Zhong R,Liao Z,Xu Q,Zhou X,Zhou X,Akin I,Zitron E,Frey N,Streckfuss-Bömeke K,Kayvanpour E, Int J Mol Sci. November 30, 2021; 22(23):1422-0067.

Discovery of a genetic module essential for assigning left-right asymmetry in humans and ancestral vertebrates., Szenker-Ravi E,Ott T,Khatoo M,Moreau de Bellaing A,Goh WX,Chong YL,Beckers A,Kannesan D,Louvel G,Anujan P,Ravi V,Bonnard C,Moutton S,Schoen P,Fradin M,Colin E,Megarbane A,Daou L,Chehab G,Di Filippo S,Rooryck C,Deleuze JF,Boland A,Arribard N,Eker R,Tohari S,Ng AY,Rio M,Lim CT,Eisenhaber B,Eisenhaber F,Venkatesh B,Amiel J,Crollius HR,Gordon CT,Gossler A,Roy S,Attie-Bitach T,Blum M,Bouvagnet P,Reversade B, Nat Genet. January 1, 2022; 54(1):1546-1718.

Functional cross-talk between phosphorylation and disease-causing mutations in the cardiac sodium channel Nav1.5., Galleano I,Harms H,Choudhury K,Khoo K,Delemotte L,Pless SA, Proc Natl Acad Sci U S A. August 17, 2021; 118(33):1091-6490.

The Ubiquitin Ligase TRAIP: Double-Edged Sword at the Replisome., Wu RA,Pellman DS,Walter JC, Trends Cell Biol. February 1, 2021; 31(2):1879-3088.

A revised mechanism of action of hyperaldosteronism-linked mutations in cytosolic domains of GIRK4 (KCNJ5)., Shalomov B,Handklo-Jamal R,Reddy HP,Theodor N,Bera AK,Dascal N, J Physiol. March 1, 2022; 600(6):0022-3751.

Uncoupling the BMP receptor antagonist function from the WNT agonist function of R-spondin 2 using the inhibitory peptide dendrimer RWd., Lee H,Lee H,Sun R,Niehrs C, J Biol Chem. February 1, 2022; 298(2):1083-351X.

Migration of antibiotic resistance genes and evolution of flora structure in the Xenopus tropicalis intestinal tract with combined exposure to roxithromycin and oxytetracycline., Lin X,Xu Y,Xu Y,Han R,Luo W,Zheng L, Sci Total Environ. May 10, 2022; 820:1879-1026.

Engineered Wnt ligands enable blood-brain barrier repair in neurological disorders., Martin M,Vermeiren S,Bostaille N,Eubelen M,Spitzer D,Vermeersch M,Profaci CP,Pozuelo E,Toussay X,Raman-Nair J,Tebabi P,America M,De Groote A,Sanderson LE,Cabochette P,Germano RFV,Torres D,Boutry S,de Kerchove d'Exaerde A,Bellefroid EJ,Phoenix TN,Devraj K,Lacoste B,Daneman R,Liebner S,Vanhollebeke B, Science. February 18, 2022; 375(6582):1095-9203.

From cohorts to molecules: Adverse impacts of endocrine disrupting mixtures., Caporale N,Leemans M,Birgersson L,Germain PL,Cheroni C,Borbély G,Engdahl E,Lindh C,Bressan RB,Cavallo F,Chorev NE,D'Agostino GA,Pollard SM,Rigoli MT,Tenderini E,Tobon AL,Trattaro S,Troglio F,Zanella M,Bergman Å,Damdimopoulou P,Jönsson M,Kiess W,Kitraki E,Kiviranta H,Nånberg E,Öberg M,Rantakokko P,Rudén C,Söder O,Bornehag CG,Demeneix B,Fini JB,Gennings C,Rüegg J,Sturve J,Testa G, Science. February 18, 2022; 375(6582):1095-9203.

Lysosomes are required for early dorsal signaling in the Xenopus embryo., Tejeda-Muñoz N,De Robertis EM, Proc Natl Acad Sci U S A. April 26, 2022; 119(17):1091-6490.

16p12.1 Deletion Orthologs are Expressed in Motile Neural Crest Cells and are Important for Regulating Craniofacial Development in Xenopus laevis., Lasser M,Bolduc J,Murphy L,O'Brien C,Lee S,Girirajan S,Lowery LA, Front Genet. January 1, 2022; 13:1664-8021.

Reduced Retinoic Acid Signaling During Gastrulation Induces Developmental Microcephaly., Gur M,Bendelac-Kapon L,Shabtai Y,Pillemer G,Fainsod A, Front Cell Dev Biol. January 1, 2022; 10:2296-634X.

Ventx Family and Its Functional Similarities with Nanog: Involvement in Embryonic Development and Cancer Progression., Kumar S,Kumar S,Kumar S,Kumar V,Li W,Kim J, Int J Mol Sci. March 1, 2022; 23(5):1422-0067.

CRISPR/Cas9-Mediated Models of Retinitis Pigmentosa Reveal Differential Proliferative Response of Müller Cells between Xenopus laevis and Xenopus tropicalis., Parain K,Lourdel S,Donval A,Chesneau A,Borday C,Bronchain O,Locker M,Perron M, Cells. February 25, 2022; 11(5):2073-4409.

Global analysis of cell behavior and protein dynamics reveals region-specific roles for Shroom3 and N-cadherin during neural tube closure., Baldwin AT,Kim JH,Seo H,Wallingford JB, Elife. March 4, 2022; 11:2050-084X.

Pharmacological characterization of novel heteromeric GluCl subtypes from Caenorhabditis elegans and parasitic nematodes., Lamassiaude N,Courtot E,Corset A,Charvet CL,Neveu C, Br J Pharmacol. March 1, 2022; 179(6):1476-5381.

Pharmacological characterization of a novel negative allosteric modulator of NMDA receptors, UBP792., Sapkota K,Burnell ES,Irvine MW,Fang G,Gawande DY,Dravid SM,Jane DE,Monaghan DT, Neuropharmacology. December 15, 2021; 201:1873-7064.

Multistep mechanism of G-quadruplex resolution during DNA replication., Sato K,Martin-Pintado N,Post H,Altelaar M,Knipscheer P, Sci Adv. September 24, 2021; 7(39):2375-2548.

Homozygous variants in PANX1 cause human oocyte death and female infertility., Wang W,Qu R,Dou Q,Wu F,Wang W,Chen B,Mu J,Zhang Z,Zhang Z,Zhang Z,Zhao L,Zhou Z,Dong J,Zeng Y,Liu R,Du J,Zhu S,Li Q,He L,Jin L,Wang L,Sang Q, Eur J Hum Genet. September 1, 2021; 29(9):1476-5438.

Inhibition of the Aquaporin-1 Cation Conductance by Selected Furan Compounds Reduces Red Blood Cell Sickling., Chow PH,Cox CD,Pei JV,Anabaraonye N,Nourmohammadi S,Henderson SW,Martinac B,Abdulmalik O,Yool AJ, Front Pharmacol. October 1, 2021; 12:1663-9812.

A transepithelial pathway delivers succinate to macrophages, thus perpetuating their pro-inflammatory metabolic state., Fremder M,Kim SW,Khamaysi A,Shimshilashvili L,Eini-Rider H,Park IS,Hadad U,Cheon JH,Ohana E, Cell Rep. August 10, 2021; 36(6):2211-1247.

PCD Genes-From Patients to Model Organisms and Back to Humans., Niziolek M,Bicka M,Osinka A,Samsel Z,Sekretarska J,Poprzeczko M,Bazan R,Fabczak H,Joachimiak E,Wloga D, Int J Mol Sci. February 3, 2022; 23(3):1422-0067.

Thyroid Hormone Receptor α Controls the Hind Limb Metamorphosis by Regulating Cell Proliferation and Wnt Signaling Pathways in Xenopus tropicalis., Tanizaki Y,Shibata Y,Zhang H,Shi YB,Shi YB, Int J Mol Sci. January 22, 2022; 23(3):1422-0067.

ATP and large signaling metabolites flux through caspase-activated Pannexin 1 channels., Narahari AK,Kreutzberger AJ,Gaete PS,Chiu YH,Leonhardt SA,Medina CB,Jin X,Oleniacz PW,Kiessling V,Barrett PQ,Ravichandran KS,Yeager M,Contreras JE,Tamm LK,Bayliss DA, Elife. January 7, 2021; 10:2050-084X.

The Ribosomal Protein L5 Functions During Xenopus Anterior Development Through Apoptotic Pathways., Schreiner C,Kernl B,Dietmann P,Riegger RJ,Kühl M,Kühl SJ, Front Cell Dev Biol. January 1, 2022; 10:2296-634X.

Identification and validation of candidate risk genes in endocytic vesicular trafficking associated with esophageal atresia and tracheoesophageal fistulas., Zhong G,Ahimaz P,Edwards NA,Hagen JJ,Faure C,Lu Q,Kingma P,Middlesworth W,Khlevner J,El Fiky M,Schindel D,Fialkowski E,Kashyap A,Forlenza S,Kenny AP,Zorn AM,Shen Y,Chung WK, HGG Adv. July 14, 2022; 3(3):2666-2477.

Cilia-localized GID/CTLH ubiquitin ligase complex regulates protein homeostasis of sonic hedgehog signaling components., Hantel F,Liu H,Fechtner L,Neuhaus H,Ding J,Arlt D,Walentek P,Villavicencio-Lorini P,Gerhardt C,Hollemann T,Pfirrmann T, J Cell Sci. May 1, 2022; 135(9):1477-9137.

Trafficking of the glutamate transporter is impaired in LRRK2-related Parkinson's disease., Iovino L,Giusti V,Pischedda F,Giusto E,Plotegher N,Marte A,Battisti I,Di Iacovo A,Marku A,Piccoli G,Bandopadhyay R,Perego C,Bonifacino T,Bonanno G,Roseti C,Bossi E,Arrigoni G,Bubacco L,Greggio E,Hilfiker S,Civiero L, Acta Neuropathol. July 1, 2022; 144(1):1432-0533.

Distinctive mechanisms of epilepsy-causing mutants discovered by measuring S4 movement in KCNQ2 channels., Edmond MA,Hinojo-Perez A,Wu X,Perez Rodriguez ME,Barro-Soria R, Elife. June 1, 2022; 11:2050-084X.

Functional analysis reveals ionotropic GABA receptor subunit RDL is a target site of ivermectin and fluralaner in the yellow fever mosquito, Aedes aegypti., Wang Q,Wang H,Zhang Y,Zhang Y,Chen J,Upadhyay A,Bhowmick B,Hang J,Wu S,Liao C,Han Q, Pest Manag Sci. October 1, 2022; 78(10):1526-4998.

Predictive assays for craniofacial malformations: evaluation in Xenopus laevis embryos exposed to triadimefon., Battistoni M,Metruccio F,Di Renzo F,Bacchetta R,Menegola E, Arch Toxicol. October 1, 2022; 96(10):0340-5761.

Metalloprotease ADAM9 cleaves ephrin-B ligands and differentially regulates Wnt and mTOR signaling downstream of Akt kinase in colorectal cancer cells., Chandrasekera P,Perfetto M,Lu C,Zhuo M,Bahudhanapati H,Li J,Chen WC,Kulkarni P,Christian L,Liu J,Yien YY,Yu C,Wei S, J Biol Chem. August 1, 2022; 298(8):1083-351X.

Pharmacological Modulation of Melanocortin 1 Receptor Signaling by Mrap Proteins in Xenopus tropicalis., Tai X,Zhang Y,Zhang Y,Yao J,Li X,Liu J,Han J,Lyu J,Lin G,Zhang C, Front Endocrinol (Lausanne). January 1, 2022; 13:1664-2392.

Adrenergic receptor signaling induced by Klf15, a regulator of regeneration enhancer, promotes kidney reconstruction., Suzuki N,Kanai A,Suzuki Y,Ogino H,Ochi H, Proc Natl Acad Sci U S A. August 16, 2022; 119(33):1091-6490.

Aquatic Freshwater Vertebrate Models of Epilepsy Pathology: Past Discoveries and Future Directions for Therapeutic Discovery., Williams RE,Mruk K, Int J Mol Sci. August 3, 2022; 23(15):1422-0067.

Functions of block of proliferation 1 during anterior development in Xenopus laevis., Gärtner C,Meßmer A,Dietmann P,Kühl M,Kühl SJ, PLoS One. August 2, 2022; 17(8):1932-6203.

Functional characterization of a novel TP53RK mutation identified in a family with Galloway-Mowat syndrome., Treimer E,Kalayci T,Schumann S,Suer I,Greco S,Schanze D,Schmeisser MJ,Kühl SJ,Zenker M, Hum Mutat. December 1, 2022; 43(12):1098-1004.

INTS13 variants causing a recessive developmental ciliopathy disrupt assembly of the Integrator complex., Mascibroda LG,Shboul M,Elrod ND,Colleaux L,Hamamy H,Huang KL,Peart N,Singh MK,Lee H,Lee H,Merriman B,Jodoin JN,Sitaram P,Lee LA,Fathalla R,Al-Rawashdeh B,Ababneh O,El-Khateeb M,Escande-Beillard N,Nelson SF,Wu Y,Tong L,Kenney LJ,Roy S,Russell WK,Amiel J,Reversade B,Wagner EJ, Nat Commun. October 13, 2022; 13(1):2041-1723.

Transcription suppression is mediated by the HDAC1-Sin3 complex in Xenopus nucleoplasmic extract., Quaas CE,Lin B,Long DT, J Biol Chem. November 1, 2022; 298(11):1083-351X.

Mink1 regulates spemann organizer cell fate in the xenopus gastrula via Hmga2., Colleluori V,Khokha MK, Dev Biol. March 1, 2023; 495:1095-564X.

The Flavonol Quercitrin Hinders GSK3 Activity and Potentiates the Wnt/β-Catenin Signaling Pathway., Predes D,Maia LA,Matias I,Araujo HPM,Soares C,Barros-Aragão FGQ,Oliveira LFS,Reis RR,Amado NG,Simas ABC,Mendes FA,Gomes FCA,Figueiredo CP,Abreu JG, Int J Mol Sci. October 11, 2022; 23(20):1422-0067.

GABAA receptor function is enhanced by Interleukin-10 in human epileptogenic gangliogliomas and its effect is counteracted by Interleukin-1β., Ruffolo G,Alfano V,Romagnolo A,Zimmer T,Mills JD,Cifelli P,Gaeta A,Morano A,Anink J,Mühlebner A,Vezzani A,Aronica E,Palma E, Sci Rep. October 26, 2022; 12(1):2045-2322.

De novo KCNA6 variants with attenuated KV 1.6 channel deactivation in patients with epilepsy., Salpietro V,Galassi Deforie V,Efthymiou S,O'Connor E,Marcé-Grau A,Maroofian R,Striano P,Zara F,Morrow MM,Reich A,Blevins A,Sala-Coromina J,Accogli A,Fortuna S,Alesandrini M,Au PYB,Singhal NS,Cogne B,Isidor B,Hanna MG,Macaya A,Kullmann DM,Houlden H,Männikkö R, Epilepsia. February 1, 2023; 64(2):1528-1167.

Amphibians as a model to study the role of immune cell heterogeneity in host and mycobacterial interactions., Paiola M,Dimitrakopoulou D,Pavelka MS,Robert J, Dev Comp Immunol. February 1, 2023; 139:1879-0089.

Hnf1b renal expression directed by a distal enhancer responsive to Pax8., Goea L,Buisson I,Bello V,Eschstruth A,Paces-Fessy M,Le Bouffant R,Chesneau A,Cereghini S,Riou JF,Umbhauer M, Sci Rep. November 19, 2022; 12(1):2045-2322.

Functional and clinical studies reveal pathophysiological complexity of CLCN4-related neurodevelopmental condition., Palmer EE,Pusch M,Picollo A,Forwood C,Nguyen MH,Suckow V,Gibbons J,Hoff A,Sigfrid L,Megarbane A,Nizon M,Cogné B,Beneteau C,Alkuraya FS,Chedrawi A,Hashem MO,Stamberger H,Weckhuysen S,Vanlander A,Ceulemans B,Rajagopalan S,Nunn K,Arpin S,Raynaud M,Motter CS,Ward-Melver C,Janssens K,Meuwissen M,Beysen D,Dikow N,Grimmel M,Haack TB,Clement E,McTague A,Hunt D,Townshend S,Ward M,Richards LJ,Simons C,Costain G,Dupuis L,Mendoza-Londono R,Dudding-Byth T,Boyle J,Saunders C,Fleming E,El Chehadeh S,Spitz MA,Piton A,Gerard B,Abi Warde MT,Rea G,McKenna C,Douzgou S,Banka S,Akman C,Bain JM,Sands TT,Wilson GN,Silvertooth EJ,Miller L,Lederer D,Sachdev R,Macintosh R,Monestier O,Karadurmus D,Collins F,Carter M,Rohena L,Willemsen MH,Ockeloen CW,Pfundt R,Kroft SD,Field M,Laranjeira FER,Fortuna AM,Soares AR,Michaud V,Naudion S,Golla S,Weaver DD,Bird LM,Friedman J,Clowes V,Joss S,Pölsler L,Campeau PM,Blazo M,Bijlsma EK,Rosenfeld JA,Beetz C,Powis Z,McWalter K,Brandt T,Torti E,Mathot M,Mohammad SS,Armstrong R,Kalscheuer VM, Mol Psychiatry. February 1, 2023; 28(2):1476-5578.

Pharmacological rescue of specific long QT variants of KCNQ1/KCNE1 channels., Zou X,Wu X,Sampson KJ,Colecraft HM,Larsson HP,Kass RS, Front Physiol. January 1, 2022; 13:1664-042X.

Genome-wide analysis of copy-number variation in humans with cleft lip and/or cleft palate identifies COBLL1, RIC1, and ARHGEF38 as clefting genes., Lansdon LA,Dickinson A,Arlis S,Liu H,Hlas A,Hahn A,Bonde G,Long A,Standley J,Tyryshkina A,Wehby G,Lee NR,Daack-Hirsch S,Mohlke K,Girirajan S,Darbro BW,Cornell RA,Houston DW,Murray JC,Manak JR, Am J Hum Genet. January 5, 2023; 110(1):1537-6605.

The H2A.Z and NuRD associated protein HMG20A controls early head and heart developmental transcription programs., Herchenröther A,Gossen S,Friedrich T,Reim A,Daus N,Diegmüller F,Leers J,Sani HM,Gerstner S,Schwarz L,Stellmacher I,Szymkowiak LV,Nist A,Stiewe T,Borggrefe T,Mann M,Mackay JP,Bartkuhn M,Borchers A,Lan J,Hake SB, Nat Commun. January 28, 2023; 14(1):2041-1723.

HNF1B Alters an Evolutionarily Conserved Nephrogenic Program of Target Genes., Grand K,Stoltz M,Rizzo L,Röck R,Kaminski MM,Salinas G,Getwan M,Naert T,Pichler R,Lienkamp SS, J Am Soc Nephrol. March 1, 2023; 34(3):1533-3450.

The SARS-CoV-2 Virus and the Cholinergic System: Spike Protein Interaction with Human Nicotinic Acetylcholine Receptors and the Nicotinic Agonist Varenicline., Carlson EC,Macsai M,Bertrand S,Bertrand D,Nau J, Int J Mol Sci. March 15, 2023; 24(6):1422-0067.

Long-QT mutations in KCNE1 modulate the 17β-estradiol response of Kv7.1/KCNE1., Erlandsdotter LM,Giammarino L,Halili A,Nikesjö J,Gréen H,Odening KE,Liin SI, Sci Adv. March 17, 2023; 9(11):2375-2548.

Dopamine-induced arrestin recruitment and desensitization of the dopamine D4 receptor is regulated by G protein-coupled receptor kinase-2., Burström V,Ågren R,Betari N,Valle-León M,Garro-Martínez E,Ciruela F,Sahlholm K, Front Pharmacol. January 1, 2023; 14:1663-9812.

Increased Hemichannel Activity Displayed by a Connexin43 Mutation Causing a Familial Connexinopathy Exhibiting Hypotrichosis with Follicular Keratosis and Hyperostosis., Crouthamel OE,Li L,Dilluvio MT,White TW, Int J Mol Sci. January 22, 2023; 24(3):1422-0067.

The phenotypic spectrum of pathogenic ATP1A1 variants expands: the novel p.P600R substitution causes demyelinating Charcot-Marie-Tooth disease., Cinarli Yuksel F,Nicolaou P,Spontarelli K,Dohrn MF,Rebelo AP,Koutsou P,Georghiou A,Artigas P,Züchner SL,Kleopa KA,Christodoulou K, J Neurol. May 1, 2023; 270(5):1432-1459.

Functional Characterization of a Spectrum of Novel Romano-Ward Syndrome KCNQ1 Variants., Rinné S,Oertli A,Nagel C,Tomsits P,Jenewein T,Kääb S,Kauferstein S,Loewe A,Beckmann BM,Decher N, Int J Mol Sci. January 10, 2023; 24(2):1422-0067.

Characteristic tetraspanin expression patterns mark various tissues during early Xenopus development., Kuriyama S,Tanaka M, Dev Growth Differ. February 1, 2023; 65(2):1440-169X.

OXGR1 is a candidate disease gene for human calcium oxalate nephrolithiasis., Majmundar AJ,Widmeier E,Heneghan JF,Daga A,Wu CW,Buerger F,Hugo H,Ullah I,Amar A,Ottlewski I,Braun DA,Jobst-Schwan T,Lawson JA,Zahoor MY,Rodig NM,Tasic V,Nelson CP,Khaliq S,Schönauer R,Halbritter J,Sayer JA,Fathy HM,Baum MA,Shril S,Mane S,Alper SL,Hildebrandt F, Genet Med. March 1, 2023; 25(3):1530-0366.

RAF1 deficiency causes a lethal syndrome that underscores RTK signaling during embryogenesis., Wong S,Tan YX,Loh AYT,Tan KY,Lee H,Lee H,Aziz Z,Nelson SF,Özkan E,Kayserili H,Escande-Beillard N,Reversade B, EMBO Mol Med. May 8, 2023; 15(5):1757-4684.

Pleiotropic role of TRAF7 in skull-base meningiomas and congenital heart disease., Mishra-Gorur K,Barak T,Kaulen LD,Henegariu O,Jin SC,Aguilera SM,Yalbir E,Goles G,Nishimura S,Miyagishima D,Djenoune L,Altinok S,Rai DK,Viviano S,Prendergast A,Zerillo C,Ozcan K,Baran B,Sencar L,Goc N,Yarman Y,Ercan-Sencicek AG,Bilguvar K,Lifton RP,Moliterno J,Louvi A,Yuan S,Deniz E,Brueckner M,Gunel M, Proc Natl Acad Sci U S A. April 18, 2023; 120(16):1091-6490.

The Splicing Factor PTBP1 Represses TP63 γ Isoform Production in Squamous Cell Carcinoma., Taylor W,Deschamps S,Reboutier D,Paillard L,Méreau A,Audic Y, Cancer Res Commun. December 1, 2022; 2(12):2767-9764.

The histone H4K20 methyltransferase SUV4-20H1/KMT5B is required for multiciliated cell differentiation in Xenopus., Angerilli A,Tait J,Berges J,Shcherbakova I,Pokrovsky D,Schauer T,Smialowski P,Hsam O,Mentele E,Nicetto D,Rupp RA, Life Sci Alliance. July 1, 2023; 6(7):2575-1077.

Exploring the Structural and Functional Diversity among FGF Signals: A Comparative Study of Human, Mouse, and Xenopus FGF Ligands in Embryonic Development and Cancer Pathogenesis., Goutam RS,Kumar V,Lee U,Kim J, Int J Mol Sci. April 20, 2023; 24(8):1422-0067.

Age-associated DNA methylation changes in Xenopus frogs., Morselli M,Bennett R,Shaidani NI,Horb M,Peshkin L,Pellegrini M, Epigenetics. December 1, 2023; 18(1):1559-2308.

TPX2 expression as a negative predictor of gemcitabine efficacy in pancreatic cancer., Guenther M,Surendran SA,Haas M,Heinemann V,von Bergwelt-Baildon M,Engel J,Werner J,Boeck S,Ormanns S, Br J Cancer. July 1, 2023; 129(1):0007-0920.

Pleiotropy of autism-associated chromatin regulators., Lasser M,Sun N,Xu Y,Xu Y,Wang S,Drake S,Law K,Gonzalez S,Wang B,Drury V,Castillo O,Zaltsman Y,Dea J,Bader E,McCluskey KE,State MW,Willsey AJ,Willsey HR, Development. July 15, 2023; 150(14):1477-9129.

Genetically programmed retinoic acid deficiency during gastrulation phenocopies most known developmental defects due to acute prenatal alcohol exposure in FASD., Petrelli B,Oztürk A,Pind M,Ayele H,Fainsod A,Hicks GG, Front Cell Dev Biol. January 1, 2023; 11:2296-634X.

Phenotype-genotype relationships in Xenopus sox9 crispants provide insights into campomelic dysplasia and vertebrate jaw evolution., Hossain N,Igawa T,Suzuki M,Suzuki M,Tazawa I,Nakao Y,Hayashi T,Suzuki N,Ogino H, Dev Growth Differ. October 1, 2023; 65(8):1440-169X.

Post-infection treatment with the E protein inhibitor BIT225 reduces disease severity and increases survival of K18-hACE2 transgenic mice infected with a lethal dose of SARS-CoV-2., Ewart G,Bobardt M,Bentzen BH,Yan Y,Thomson A,Klumpp K,Becker S,Rosenkilde MM,Miller M,Gallay P, PLoS Pathog. August 1, 2023; 19(8):1553-7374.

Rare variants in CAPN2 increase risk for isolated hypoplastic left heart syndrome., Blue EE,White JJ,Dush MK,Gordon WW,Wyatt BH,White P,Marvin CT,Helle E,Ojala T,Priest JR,Jenkins MM,Almli LM,Reefhuis J,Pangilinan F,Brody LC,McBride KL,Garg V,Shaw GM,Romitti PA,Nembhard WN,Browne ML,Werler MM,Kay DM,Mital S,Chong JX,Nascone-Yoder NM,Bamshad MJ, HGG Adv. October 12, 2023; 4(4):2666-2477.

Inactivation influences the extent of inhibition of voltage-gated Ca+2 channels by Gem-implications for channelopathies., Allam S,Levenson-Palmer R,Chia Chang Z,Kaur S,Cernuda B,Raman A,Booth A,Dobbins S,Suppa G,Yang J,Buraei Z, Front Physiol. January 1, 2023; 14:1664-042X.

Time-resolved quantitative proteomic analysis of the developing Xenopus otic vesicle reveals putative congenital hearing loss candidates., Baxi AB,Nemes P,Moody SA, iScience. September 15, 2023; 26(9):2589-0042.

TBC1D32 variants disrupt retinal ciliogenesis and cause retinitis pigmentosa., Bocquet B,Borday C,Erkilic N,Mamaeva D,Donval A,Masson C,Parain K,Kaminska K,Quinodoz M,Perea-Romero I,Garcia-Garcia G,Jimenez-Medina C,Boukhaddaoui H,Coget A,Leboucq N,Calzetti G,Gandolfi S,Percesepe A,Barili V,Uliana V,Delsante M,Bozzetti F,Scholl HP,Corton M,Ayuso C,Millan JM,Rivolta C,Meunier I,Perron M,Kalatzis V, JCI Insight. November 8, 2023; 8(21):2379-3708.

ADAM11 a novel regulator of Wnt and BMP4 signaling in neural crest and cancer., Pandey A,Cousin H,Horr B,Alfandari D,Alfandari D, Front Cell Dev Biol. January 1, 2023; 11:2296-634X.

Deleterious functional consequences of perfluoroalkyl substances accumulation into the myelin sheath., Butruille L,Jubin P,Martin E,Aigrot MS,Lhomme M,Fini JB,Demeneix B,Stankoff B,Lubetzki C,Zalc B,Remaud S, Environ Int. October 1, 2023; 180:0160-4120.

Generation of translucent Xenopus tropicalis through triple knockout of pigmentation genes., Nakajima K,Tazawa I,Furuno N, Dev Growth Differ. December 1, 2023; 65(9):1440-169X.

Xenopus Ssbp2 is required for embryonic pronephros morphogenesis and terminal differentiation., Cervino AS,Collodel MG,Lopez IA,Roa C,Hochbaum D,Hukriede NA,Cirio MC, Sci Rep. October 4, 2023; 13(1):2045-2322.

Estimating the true stability of the prehydrolytic outward-facing state in an ABC protein., Simon MA,Iordanov I,Szollosi A,Csanády L, Elife. October 2, 2023; 12:2050-084X.

The structural mechanism of dimeric DONSON in replicative helicase activation., Cvetkovic MA,Passaretti P,Butryn A,Reynolds-Winczura A,Kingsley G,Skagia A,Fernandez-Cuesta C,Poovathumkadavil D,George R,Chauhan AS,Jhujh SS,Stewart GS,Gambus A,Costa A, Mol Cell. November 16, 2023; 83(22):1097-4164.

The USP46 complex deubiquitylates LRP6 to promote Wnt/β-catenin signaling., Ng VH,Spencer Z,Neitzel LR,Nayak A,Loberg MA,Shen C,Kassel SN,Kroh HK,An Z,Anthony CC,Bryant JM,Lawson A,Goldsmith L,Benchabane H,Hansen AG,Li J,D'Souza S,Lebensohn AM,Rohatgi R,Weiss WA,Weiss VL,Williams C,Hong CC,Robbins DJ,Ahmed Y,Lee E,Lee E, Nat Commun. October 5, 2023; 14(1):2041-1723.

Advancements in the use of xenopus oocytes for modelling neurological disease for novel drug discovery., O'Connor EC,Kambara K,Bertrand D, Expert Opin Drug Discov. February 1, 2024; 19(2):1746-045X.

FGFR1 variants contributed to families with tooth agenesis., Yao S,Zhou X,Zhou X,Gu M,Zhang C,Bartsch O,Vona B,Fan L,Ma L,Pan Y, Hum Genomics. October 13, 2023; 17(1):1479-7364.

Using Xenopus to discover new candidate genes involved in BOR and other congenital hearing loss syndromes., Neal SJ,Rajasekaran A,Jusić N,Taylor L,Read M,Alfandari D,Alfandari D,Pignoni F,Moody SA, J Exp Zool B Mol Dev Evol. October 13, 2023; :1552-5015.

Zmym4 is required for early cranial gene expression and craniofacial cartilage formation., Jourdeuil K,Neilson KM,Cousin H,Tavares ALP,Majumdar HD,Alfandari D,Alfandari D,Moody SA, Front Cell Dev Biol. January 1, 2023; 11:2296-634X.

Small molecule-mediated reprogramming of Xenopus blastula stem cells to a neural crest state., Huber PB,LaBonne C, Dev Biol. January 1, 2024; 505:1095-564X.

GRIN2A mutation and early-onset epileptic encephalopathy: personalized therapy with memantine., Pierson TM,Yuan H,Marsh ED,Fuentes-Fajardo K,Adams DR,Markello T,Golas G,Simeonov DR,Holloman C,Tankovic A,Karamchandani MM,Schreiber JM,Mullikin JC,Tifft CJ,Toro C,Boerkoel CF,Traynelis SF,Gahl WA, Ann Clin Transl Neurol. March 1, 2014; 1(3):2328-9503.

Remarkable effect of transdermal nicotine in children with CHRNA4-related autosomal dominant sleep-related hypermotor epilepsy., Lossius K,de Saint Martin A,Myren-Svelstad S,Bjørnvold M,Minken G,Seegmuller C,Valenti Hirsch MP,Chelly J,Steinlein O,Picard F,Brodtkorb E, Epilepsy Behav. April 1, 2020; 105:1525-5069.

Mertk-expressing microglia influence oligodendrogenesis and myelin modelling in the CNS., Nguyen LT,Aprico A,Nwoke E,Walsh AD,Blades F,Avneri R,Martin E,Zalc B,Kilpatrick TJ,Binder MD, J Neuroinflammation. November 6, 2023; 20(1):1742-2094.

Bi-allelic ACBD6 variants lead to a neurodevelopmental syndrome with progressive and complex movement disorders., Kaiyrzhanov R,Rad A,Lin SJ,Bertoli-Avella A,Kallemeijn WW,Godwin A,Zaki MS,Huang K,Lau T,Petree C,Efthymiou S,Karimiani EG,Hempel M,Normand EA,Rudnik-Schöneborn S,Schatz UA,Baggelaar MP,Ilyas M,Sultan T,Alvi JR,Ganieva M,Fowler B,Aanicai R,Tayfun GA,Al Saman A,Alswaid A,Amiri N,Asilova N,Shotelersuk V,Yeetong P,Azam M,Babaei M,Monajemi GB,Mohammadi P,Samie S,Banu SH,Pinto Basto J,Kortüm F,Bauer M,Bauer P,Beetz C,Garshasbi M,Issa AH,Eyaid W,Ahmed H,Hashemi N,Hassanpour K,Herman I,Ibrohimov S,Abdul-Majeed BA,Imdad M,Isrofilov M,Kaiyal Q,Khan S,Kirmse B,Koster J,Lourenço CM,Mitani T,Moldovan O,Murphy D,Najafi M,Pehlivan D,Rocha ME,Salpietro V,Schmidts M,Shalata A,Mahroum M,Talbeya JK,Taylor RW,Vazquez D,Vetro A,Waterham HR,Zaman M,Schrader TA,Chung WK,Guerrini R,Lupski JR,Gleeson J,Suri M,Jamshidi Y,Bhatia KP,Vona B,Schrader M,Severino M,Guille M,Tate EW,Varshney GK,Houlden H,Maroofian R, Brain. April 4, 2024; 147(4):1460-2156.

Enhanced C-To-T and A-To-G Base Editing in Mitochondrial DNA with Engineered DdCBE and TALED., Wei Y,Jin M,Huang S,Yao F,Ren N,Xu K,Li S,Gao P,Zhou Y,Chen Y,Chen Y,Yang H,Li W,Xu C,Zhang M,Wang X, Adv Sci (Weinh). January 1, 2024; 11(3):2198-3844.

Functional and clinical characterization of a novel homozygous KCNH2 missense variant in the pore region of Kv11.1 leading to a viable but severe long-QT syndrome., Delinière A,Jaupart L,Janin A,Millat G,Boulin T,Andrini O,Chevalier P, Gene. March 1, 2024; 897:1879-0038.

Enhanced Membrane Incorporation of H289Y Mutant GluK1 Receptors from the Audiogenic Seizure-Prone GASH/Sal Model: Functional and Morphological Impacts on Xenopus Oocytes., Díaz-Rodríguez SM,Ivorra I,Espinosa J,Vegar C,Herrero-Turrión MJ,López DE,Gómez-Nieto R,Alberola-Die A, Int J Mol Sci. November 28, 2023; 24(23):1422-0067.

Alcohol induces neural tube defects by reducing retinoic acid signaling and promoting neural plate expansion., Edri T,Cohen D,Shabtai Y,Fainsod A, Front Cell Dev Biol. January 1, 2023; 11:2296-634X.

Selective block of human Kv1.1 channels and an epilepsy-associated gain-of-function mutation by AETX-K peptide., Zhao R,Qasim A,Sophanpanichkul P,Dai H,Nayak M,Sher I,Chill J,Goldstein SAN, FASEB J. January 1, 2024; 38(1):1530-6860.

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