Figure 2. The cytoplasmic tail of rhodopsin can redirect GFP to the ROS. Confocal micrographs of transgenic retinas expressing GFP and GFP-CT44. Nuclei were stained with Hoescht 33342. (A) GFP distributed predominantly to the cytoplasm of the inner segment (is) and nucleoplasm. GFP resided at low levels in the outer segment (os) and was not associated with membranes. (B) GFP-CT44 localized almost exclusively to the outer segments. GFP (green) and Hoescht 33342 (blue). n, nucleus; m, mitochondria; and s, synaptic terminal. Bar, 5 μm.
Image published in: Tam BM et al. (2000)
© 2000 The Rockefeller University Press. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license
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