Figure 3. The peripherin targeting sequence redirects the subcellular targeting of the Htr1a serotonin receptor.Panels show confocal images of transgenic frog retinas expressing YFP-fused Htr1a constructs (green) schematically illustrated above each panel. (A) Htr1a-YFP; fluorescent signal observed in calycal processes is marked by white arrows. (B) Htr1a-YFP containing the Per327–336 sequence fused at the C-terminus. (C) Same construct as in (B), but bearing the V332A mutation. Abbreviations are: OS – outer segment, IS – inner segment, N – nuclei, ST – synaptic termini. Nuclei (blue) are stained with Hoechst. Scale bar: 5 µm.
Image published in: Salinas RY et al. (2013)
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