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Fig. 3. Comparison of ATP sensitivities. (a) IC50 for MgATP inhibition and (b) fraction of unblocked current at 3 mmol/l MgATP for the indicated channels: WT (n = 13), homE23K (n = 5), hetG324R (n = 6), homG324R (n = 8), hetE227L (n = 7). Mean values for TNDM (white hatched bars), PNDM (grey hatched bars) and DEND/iDEND (grey bars) channels are given for comparison (for references, see ESM Fig. 1). Data are mean ± SEM. **p < 0.01 compared with WT (t test)

Image published in: Vedovato N et al. (2016)

© The Author(s) 2016. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license

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