Fig. 1. Sequence and structure comparison of Runx3 proteins across species. (A) The predicted amino acid sequences from Xenopus laevis, human, mouse and zebrafish Runx3 were aligned using ClustalW. Conserved amino acids in all four species or in at least two species are highlighted in black and grey, respectively. The runt domain, signature motif of this class of molecules, is underlined in red. (B) Phylogenetic tree analysis of Runx proteins from Xenopus laevis (Xl), human (Hs), mouse (Mm), chicken (Gg) and zebrafish (Dr). Accession numbers for the source sequences are indicated in materials and methods.
Image published in: Park BY and Saint-Jeannet JP (2010)
Copyright © 2010. Image reproduced with permission of the Publisher, Elsevier B. V.
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