Supplementary Figure 3 – Posterior neural marker gene expression is reduced at early stages in sall morphants Splice-blocking sall1 and sall4 morpholinos induce partial loss of posterior neural marker gene expression, as assayed by whole-mount RNA in situ hybridization at stage 13 using markers hoxb9 (A-D) and hoxd10 (E-H); dorsal view, anterior up. Splice-blocking sall1 and sall4 morpholinos were injected unilaterally into the embryos shown here. Representative images are shown. Asterisks in images indicate injected side; arrows indicate partial loss of expression. Expression of hoxb9 in sall morphants at later stages is shown in Figure 2 and Supplementary Figure 2.
Image published in: Exner CRT et al. (2017)
Copyright © 2017. Image reproduced with permission of the Publisher, Elsevier B. V.
| Gene | Synonyms | Species | Stage(s) | Tissue |
|---|---|---|---|---|
| hoxb9.L | hox 2.5, xhoxb9, XlHbox-6, XlHbox6 | X. laevis | Throughout NF stage 13 | posterior neural plate |
| hoxd10.L | hox-4.4, hox4, hox4d, hox4e, LOC116406456, Xhoxd10 | X. laevis | Throughout NF stage 13 | posterior neural plate |
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