Supplementary Figure 6 (A) Knock-down of PGAM5 by siRNA transfection strongly enhanced responsiveness of murine C2C12 cells to WNT3A stimulation as determined by TOP-Flash reporter gene assays normalized to β-Galactosidase. (B) PGAM5 knock-down in HEK293T cells resulted in stabilization of cytoplasmic β-Catenin and upregulation of the feedback target AXIN2.
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