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Figure 2. (A–F) Expression of lhx1 on the control side and nephrectomized side at 24, 48, and 96 hr after nephrectomy. N indicates the number of examined embryos. (D) lhx1 expression appears in regenerating nephric tubules within 24 hr (arrows). (E, F) This expression becomes stronger around 48 hr but disappears at 96 hr. (G–L) Expression of pax8. pax8 expression appears in regenerating nephric tubules and is still detected at 96 hr after nephrectomy. (M–R) Expression of pax2 is not observed at 24 hr after nephrectomy (P, arrow). (S) Quantification of expression signals for lhx1, pax8, and pax2. The significance of differences between the control side and the nephrectomized side at 48 hr is calculated by two-tailed paired t-test (lhx1: p=0.0414; pax8: p=0.0102; pax2: p=0.0453). Lines in boxes indicate the median.

Image published in: Suzuki N et al. (2019)

Image downloaded from an Open Access article in PubMed Central. © 2019, Suzuki et al

GeneSynonymsSpeciesStage(s)Tissue
lhx1.LXlim1, Xlim-1, Lim1, lim-1, lim1X.laevisSometime during NF stage 41 to NF stage 42pronephric duct
pronephric kidney
lhx1.LXlim1, Xlim-1, Lim1, lim-1, lim1X.laevisSometime during NF stage 45 to NF stage 46pronephric duct
pronephric kidney
pax8.LXPax8, XPax-8, pax-8X.laevisSometime during NF stage 41 to NF stage 42pronephric tubule
pax8.LXPax8, XPax-8, pax-8X.laevisSometime during NF stage 45 to NF stage 46pronephric tubule
pax8.LXPax8, XPax-8, pax-8X.laevisSometime during NF stage 47 to NF stage 48pronephric tubule
pax2.LXPax2, XPax-2, pax-2, pax2-a, pax2-bX.laevisSometime during NF stage 41 to NF stage 42pronephric tubule
pronephric nephrostome
pronephric duct
pax2.LXPax2, XPax-2, pax-2, pax2-a, pax2-bX.laevisSometime during NF stage 45 to NF stage 46pronephric nephrostome
pronephric duct
pronephric tubule
pax2.LXPax2, XPax-2, pax-2, pax2-a, pax2-bX.laevisSometime during NF stage 47 to NF stage 48pronephric kidney

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