Fig. 2. (A) Whole-mount in situ hybridization with labeled antisense probes against XMEF2D, XMEF2A and XMEF2C during embryonic development. The numbers refer to the developmental stages. The anterior side of the embryos is on the left. Lateral view for all embryos except dorsal view for XMEF2D stages 12, 16 and 20; XMEF2A stages 16 and 20; and anterior view for XMEF2C stage 19. (B) XMEF2A, XMEF2D and XMEF2C expression at stages 37â38 in head muscle anlagens as indicated by XMRF4 mRNAs localization. Lateral view on the left. ba, brachial arches; cm, cranio-facial muscle; fhr, frontal head region; nc, neural crest; h, heart; hm, hypaxial muscles. Arrowhead: hypaxial migratory cells.
Image published in: della Gaspera B et al. (2009)
Copyright © 2009. Image reproduced with permission of the Publisher, Elsevier B. V.
| Gene | Synonyms | Species | Stage(s) | Tissue |
|---|---|---|---|---|
| mef2d.S | mef2d-a, mef2d-b, sl1, XMEF2D | X. laevis | Throughout NF stage 12 | presomitic mesoderm |
| mef2a.L | adcad1, rsrfc4, rsrfc9, sl2, xmef2a | X. laevis | Sometime during NF stage 16 to NF stage 20 | presomitic mesoderm neural plate |
| mef2d.S | mef2d-a, mef2d-b, sl1, XMEF2D | X. laevis | Sometime during NF stage 16 to NF stage 20 | neural plate mesoderm |
| mef2c.L | XMEF2C | X. laevis | Sometime during NF stage 19 to NF stage 22 | cranial neural crest |
| mef2a.L | adcad1, rsrfc4, rsrfc9, sl2, xmef2a | X. laevis | Sometime during NF stage 23 to NF stage 29 and 30 | somite trunk somite mesoderm muscle myotome |
| mef2d.S | mef2d-a, mef2d-b, sl1, XMEF2D | X. laevis | Throughout NF stage 25 | mesoderm somite heart primordium |
| mef2c.L | XMEF2C | X. laevis | Throughout NF stage 28 | cranial neural crest mandibular crest branchial crest hyoid crest heart primordium |
| mef2d.S | mef2d-a, mef2d-b, sl1, XMEF2D | X. laevis | Throughout NF stage 29 and 30 | head head region muscle myotome somite branchial arch |
| mef2c.L | XMEF2C | X. laevis | Throughout NF stage 29 and 30 | muscle somite branchial arch |
| mef2d.S | mef2d-a, mef2d-b, sl1, XMEF2D | X. laevis | Throughout NF stage 32 | head region muscle somite hatching gland heart primordium tail somite optic vesicle |
| mef2a.L | adcad1, rsrfc4, rsrfc9, sl2, xmef2a | X. laevis | Throughout NF stage 32 | head region muscle myotome somite trunk somite |
| mef2c.L | XMEF2C | X. laevis | Throughout NF stage 33 and 34 | head region muscle myotome somite trunk somite |
| mef2c.L | XMEF2C | X. laevis | Throughout NF stage 35 and 36 | head region muscle myotome somite hypaxial muscle heart primordium |
| myf6.L | herculin, mrf4, myf6-a, myf6-b, Xmrf4, XMRF4-a, XMRF4a | X. laevis | Throughout NF stage 37 and 38 | head region muscle |
| mef2a.L | adcad1, rsrfc4, rsrfc9, sl2, xmef2a | X. laevis | Sometime during NF stage 37 and 38 to NF stage 40 | head region muscle myotome somite hypaxial muscle head mesoderm |
| mef2c.L | XMEF2C | X. laevis | Sometime during NF stage 37 and 38 to NF stage 40 | head region muscle somite hypaxial muscle |
| mef2d.S | mef2d-a, mef2d-b, sl1, XMEF2D | X. laevis | Throughout NF stage 37 and 38 to NF stage 40 | head region muscle somite hypaxial muscle tail region |
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