Figure 5. Sox9 is expressed throughout the otic vesicle and in the developing semicircular canals. Developmental expression of Sox9 in the otocyst of wild type embryos by whole-mount in situ hybridization (A,B,D) and by in situ hybridization on section (C,E-I). The embryonic stage (Nieuwkoop and Faber,[1967]) is indicated in the upper right corner of each panel. A-H: Sox9 is initially expressed throughout the entire otic epithelium (A-C) and then become progressively restricted to the dorsal and ventral aspects of the otic vesicle (D-H). I: At stage 45, Sox9 is also detected in the protrusions of the developing semicircular canals (arrow). In all panels, dorsal to top. For whole embryos staining anterior is to the right. Scale bars = 300 mu m in A,B,D; 50 mu m in C,E.I.
Image published in: Park BY and Saint-Jeannet JP (2010)
Copyright © 2010. Image reproduced with permission of the Publisher, John Wiley & Sons.
| Gene | Synonyms | Species | Stage(s) | Tissue |
|---|---|---|---|---|
| sox9.S | cmd1, cmpd1, sox-9, sox9-a, sox9-b, sra1 | X. laevis | Throughout NF stage 15 | otic region lateral epibranchial placode lateral line placode |
| sox9.S | cmd1, cmpd1, sox-9, sox9-a, sox9-b, sra1 | X. laevis | Throughout NF stage 24 | otic region otic vesicle otic placode epibranchial placode lateral line placode olfactory placode eye primordium |
| sox9.S | cmd1, cmpd1, sox-9, sox9-a, sox9-b, sra1 | X. laevis | Sometime during NF stage 27 to NF stage 40 | otic vesicle epithelium epibranchial placode lateral line placode optic vesicle dorsal ventral brain hindbrain midbrain-hindbrain boundary pineal gland olfactory region |
| sox9.S | cmd1, cmpd1, sox-9, sox9-a, sox9-b, sra1 | X. laevis | Throughout NF stage 45 | semicircular canal otic vesicle inner ear epithelium auditory apparatus ventral dorsal |
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