Larger Image Fig. 4. Coco RNA prevents expression of left side markers. Embryos were injected on the left dorsal side of four-cell stage embryos with Coco RNA (10 pg) and collected at stage 24. In situ hybridization for Pitx2c (A, B) and Xnr1 (C, D). Left and right sides of the same embryos are shown. Arrowheads in panels C and D indicate the posterior, bilateral expression domain of Xnr1, not affected by Coco RNA. Image published in: Vonica A and Brivanlou AH (2007) Copyright © 2007. Image reproduced with permission of the Publisher, Elsevier B. V.
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