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Fig. 1. Geminin regulates epidermal, mesodermal and endodermal gene expression. Geminin RNA or morpholino/MO-injected regions are oriented rightwards, indicated by yellow arrowheads, and lineage is labeled by β-galactosidase RNA co-injection and Red-gal (Mix.2, Brachyury/Xbra, and Sox17 at stage 11) or X-gal staining. Embryos are stage 10.5-11, except for Epidermal keratin/Epiker and Sox17 (right), which are stage 12-13. Views are indicated: (veg, vegetal; post, posterior).

Image published in: Lim JW et al. (2011)

Copyright © 2011. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License.

GeneSynonymsSpeciesStage(s)Tissue
krt12.4.Lck81, cytok, cytokeratin, E-keratin, epi-keratin, epidermal keratin, Epidermis-specific keratin, EpiK, epiker, EpK, epK, K81, xK81, xk81a, xk81a1X. laevisThroughout NF stage 12 to NF stage 13animal cap
ectoderm
a2m.SA2Moo, Alpha2-macroglobulin, edd, endod, endodermin, LOC108695707, ovomacroglobulinX. laevisThroughout NF stage 10.5 to NF stage 11blastopore lip
mix1.Smix.1, mix.2, mix2, tMixX. laevisThroughout NF stage 10.5 to NF stage 11dorso-lateral marginal zone
dorsal marginal zone
sox17a.Lsox17 alpha, sox17-alpha, Sox17alpha, tSox17alpha, xsox17, Xsox17-alpha, xsox17a, Xsox17alpha, xSox17alpha1, xSox17alpha2X. laevisThroughout NF stage 12 to NF stage 13endoderm
tbxt.Sbra, brachyury, ntl, t, t-a, t-b, X-bra, Xbra, XbrachyuryX. laevisThroughout NF stage 10.5 to NF stage 11mesoderm
hhex.Lhex, tHex, XHexX. laevisThroughout NF stage 10.5 to NF stage 11endomesoderm
post.LLOC108704914, XpoX. laevisThroughout NF stage 12 to NF stage 13blastopore
ventral marginal zone
ventro-lateral marginal zone
dorso-lateral marginal zone
dorsal marginal zone

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