Figure 5. ATP4 Is Required for Wnt/β-cat-Mediated Induction of Foxj1 During Gastrulation(A�C). Reduced mRNA expression of (A) Foxj1 in the SM of ATP4a-morphant or SCH28080-treated embryos was rescued upon coinjection of (B) a β-cat DNA expression construct. (C) Ectopic expression of Foxj1 on the ventral lip following injection of a β-cat DNA expression construct into ventral blastomeres at the four-cell stage (VMZ lineage).(D) Quantification of results.(E) Partial rescue of Pitx2c expression in ATP4a morphants upon coinjection of a Foxj1 DNA expression construct.See also Figure S4.
Image published in: Walentek P et al. (2012)
Copyright © 2012. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License.
| Gene | Synonyms | Species | Stage(s) | Tissue |
|---|---|---|---|---|
| foxj1.L | foxj1-a, foxj1-b, hfh-4, hfh4, xfoxj1 | X. laevis | Throughout NF stage 10.5 | dorsal marginal zone |
Image source: Published
| Experiment + Assay | Source | Phenotypes and Disease | ||
|---|---|---|---|---|
| Xla Wt + atp4a MO + NF10.5 (in situ hybridization) | fig.5.a, d |
| ||
| Xla Wt + SCH28080 + NF10.5 (in situ hybridization) | fig.5.a, d |
| ||
| Xla Wt + ctnnb1-GFP + NF10.5 (in situ hybridization) | fig.5.c |
|
Permanent Image Page
Printer Friendly View
XB-IMG-82877