Figure 3. A catalog of the mutations found in a single albino CRISPR/Cas embryo. The wild-type sequence (parental) is shown at the top. Nineteen PCR product sequences are shown. Red highlighted bases indicate the target site with the PAM sequence in black bold and underlined. The nature of the mutations is indicated in the right column. Δ, deletion; sub, substitutions; WT, wild-type. *Clone 7 has a complex mutation consisting of a direct imperfect repeat of 19 base pairs (underlined).
Image published in: Blitz IL et al. (2013)
Copyright © 2013. Image reproduced with permission of the Publisher, John Wiley & Sons.
Permanent Image Page
Printer Friendly View
XB-IMG-84492