Figure 3. Tel1 Is Required for the Programming of Adult Hemangioblasts in the Lpm (A) Expression analysis showing that Tel1 is expressed in the DLP (arrows) at the time adult hemangioblasts are specified. (B) Analysis of hematopoietic expression in the DLP of Tel1 morphants. Tel1 is dispensable for Gata2 and Lmo2 expression, but required for Scl expression in the DLP (arrows). Arrowheads indicate expression in embryonic erythrocytes located in the ventral blood island. (C) Analysis of endothelial expression in the DLP of Tel1 morphants. Tel1 is required for DLP expression of Flt1 and Flt4, but not Flk1 (arrows). All embryos were hybridized as whole mounts and are shown in lateral view, with anterior to the left and dorsal to the top. Stages of development are as indicated. The numbers of embryos represented by each panel, out of the number analyzed, are indicated in the top right corner. See also Figure S1 and Table S1.
Image published in: Ciau-Uitz A et al. (2010)
Copyright © 2010. Image reproduced with permission of the Publisher, Elsevier B. V.
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