Fig. 2. Expression of nIF mRNA in the contralateral, unoperated control eye at late stages of regeneration (A–E) and in the operated eye 6 (F–J) and 12 (K–O) days after optic nerve crush. Neighboring transverse sections were hybridized with digoxigenin-labeled cRNA probes to peripherin (A,F,K), xefiltin (B,G,L), XNIF (C,H,M), NF-M (D,I,N), and NF-L (E,J,O). A representative example of a section from an operated eye hybridized with a sense probe to peripherin showed no label above background (P). i, inner nuclear layer; p, retinal pigmented epithelium (naturally pigmented and not labeled); r, retinal ganglion cell (RGC) layer. Scale bar 100 m in P and applies to all panels.
Image published in: Gervasi C et al. (2003)
Copyright © 2003. Image reproduced with permission of the Publisher, John Wiley & Sons.
| Gene | Synonyms | Species | Stage(s) | Tissue |
|---|---|---|---|---|
| ina.S | ina-a, inexa, nifa, xefiltin, xina | X. laevis | Throughout NF stage 66 | retinal ganglion cell layer retinal ganglion cell retina eye |
| prph.L | nef4, peripherin, XIF3 | X. laevis | Throughout NF stage 66 | |
| nef1f.L | nif | X. laevis | Throughout NF stage 66 | eye retina retinal ganglion cell layer retinal ganglion cell |
| nefm.L | nef-m, nef3, nefm-a, nefm-b, nf-m | X. laevis | Throughout NF stage 66 | eye retina retinal ganglion cell layer retinal ganglion cell |
| nefl.L | NF-L, XNF-L | X. laevis | Throughout NF stage 66 | eye retina retinal ganglion cell layer retinal ganglion cell |
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