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Figure 6. Analysis of the spatial expression patterns of the intracellular fgfs and hormone-like fgfs subfamilies. A: Whole mount in situ hybridisations of fgf12, fgf13, and fgf14 at the indicated stages. B: Whole mount of the hormone-like fgfs at the indicated stages. For stage 10.5, the images are vegetal views; for stage 15, the images are dorsal views; and for stage 23, 28, 35, and 40, the images are lateral views (anterior is left, posterior is right, dorsal is up, and ventral is down). A schematic representation of a Xenopus embryo at stage 28 with the different embryonic tissues labelled is presented in Supp. Figure S3.

Image published in: Lea R et al. (2009)

Copyright © 2009. Image reproduced with permission of the Publisher, John Wiley & Sons.

GeneSynonymsSpeciesStage(s)Tissue
fgf12X.tropicalisThroughout NF stage 10.5dorsal
ectoderm
fgf12X.tropicalisThroughout NF stage 15neural plate
fgf12X.tropicalisThroughout NF stage 23eye
olfactory placode
fgf12X.tropicalisSometime during NF stage 28 to NF stage 35 and 36eye
olfactory placode
anterior neural tube
head region
fgf12X.tropicalisThroughout NF stage 40eye
head region
olfactory placode
fgf13mgc81084, fgf13.1X.tropicalisThroughout NF stage 10.5ectoderm
fgf13mgc81084, fgf13.1X.tropicalisThroughout NF stage 15neural plate
fgf13mgc81084, fgf13.1X.tropicalisThroughout NF stage 23neural tube
intersomitic region
trigeminal placode
fgf13mgc81084, fgf13.1X.tropicalisThroughout NF stage 28eye
neural tube
trigeminal placode
fgf13mgc81084, fgf13.1X.tropicalisSometime during NF stage 35 and 36 to NF stage 40lens
forebrain
eye
neural tube
intersomitic region
neurogenic placode
trigeminal ganglion
fgf14fhf4, sca27X.tropicalisThroughout NF stage 10.5mesoderm
ectoderm
fgf14fhf4, sca27X.tropicalisThroughout NF stage 15caudal presomitic mesoderm
fgf14fhf4, sca27X.tropicalisThroughout NF stage 23intersomitic region
head region
fgf14fhf4, sca27X.tropicalisThroughout NF stage 28eye
intersomitic region
neurogenic placode
profundal placode
trigeminal placode
pharyngeal arch
fgf14fhf4, sca27X.tropicalisThroughout NF stage 35 and 36trigeminal ganglion
profundus ganglion
eye
lens
intersomitic region
pineal gland
fgf14fhf4, sca27X.tropicalisThroughout NF stage 40intersomitic region
head mesenchyme
fgf19fgf-19X.tropicalisThroughout NF stage 10.5ectoderm
mesoderm
fgf19fgf-19X.tropicalisThroughout NF stage 15neural plate
anterior placodal area
posterior
mesoderm
fgf19fgf-19X.tropicalisThroughout NF stage 23tail bud
eye
anterior neural tube
fgf19fgf-19X.tropicalisSometime during NF stage 28 to NF stage 35 and 36eye
head region
fgf19fgf-19X.tropicalisThroughout NF stage 40head
eye
fgf23.1fgf23X.tropicalisThroughout NF stage 10.5dorsal
ectoderm
fgf23.1fgf23X.tropicalisThroughout NF stage 15neural plate
fgf23.1fgf23X.tropicalisSometime during NF stage 23 to NF stage 28eye
cranial neural crest
neural tube
pronephric mesenchyme
head region
epidermis
fgf23.1fgf23X.tropicalisThroughout NF stage 35 and 36otic vesicle
eye
pharyngeal region
head region
fgf23.1fgf23X.tropicalisThroughout NF stage 40lens
eye
head

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