Images

Sources

Experiment + Assay

Phenotypes

Human Diseases

Fig. 1 b row2

Yasuoka Y et al. (2014)

Xtr Wt + otx2 MO + crx MO + gsc MO + lhx1 MO

NF31-32 (whole-mount microscopy)

Anatomical Phenotype
abnormal forebrain abnormal foregut morphology abnormal head morphology absent eye absent optic stalk decreased size of the forebrain decreased size of the midbrain-hindbrain boundary

Expression Phenotype
absent eomes expression in optic stalk

fig.S1

Rankin SA et al. (2011)

Xla Wt + lhx1 MO

NF33/34-35 and 36 (morphology)

Anatomical Phenotype
abnormal gastrulation abnormal head morphology abnormal tail morphology abnormal ventral trunk morphology

fig.6, Table 4

Rana AA et al. (2006)

Xtr Wt + lhx1 MO

tailbud stage (morphology)

Anatomical Phenotype
abnormal head morphology abnormal tail bud morphology abnormal tail morphology decreased length of anterior-posterior axis