abnormal left-right organizer morphology
has
3
anatomical phenotype(s)
Images
Sources
Experiment + Assay
Phenotypes
Human Diseases
Fig. 3 A-H, L, M
Sempou E et al. (2018)
Xtr Wt + fgfr4 CRISPR
NF17 (immunohistochemistry)
Anatomical Phenotype
abnormal gastrocoel roof plate morphology
abnormal left-right organizer morphology
abnormally decreased number of cilium in the left-right organizer
congenital heart disease
visceral heterotaxy
Fig. 3 I-K
Sempou E et al. (2018)
Xtr Wt + fgfr4 CRISPR
NF17 (immunohistochemistry)
Anatomical Phenotype
abnormal gastrocoel roof plate morphology
abnormal left-right organizer morphology
decreased size of the presomitic mesoderm
Expression Phenotype
decreased amount
myod1
expression in gastrocoel roof plate
decreased amount
myod1
expression in left-right organizer
congenital heart disease
visceral heterotaxy
Fig. S 2 A, B
Sempou E et al. (2018)
Xtr Wt + fgfr4 CRISPR
NF17 (immunohistochemistry)
Anatomical Phenotype
abnormal gastrocoel roof plate morphology
abnormal left-right organizer morphology
abnormally decreased number of cilium in the left-right organizer
Expression Phenotype
decreased amount
tuba4b
expression in left-right organizer
congenital heart disease
visceral heterotaxy
