Fig.7.B

Gur M et al. (2022)

Xla Wt + aldh1a2 CRISPR

NF10.25 (RT-PCR)

Expression Phenotype
decreased amount aldh1a2.L expression in the embryo decreased amount admp.L expression in the embryo decreased amount aldh1a3.L expression in embryo decreased amount dkk1.L expression in embryo decreased amount frzb.L expression in the embryo decreased amount gsc.L expression in the embryo decreased amount hoxa1.L expression in embryo decreased amount hoxb4.L expression in embryo

Fig.7.C

Gur M et al. (2022)

Xla Wt + aldh1a2 CRISPR

NF12 (RT-PCR)

Expression Phenotype
decreased amount aldh1a2.L expression in the embryo decreased amount cer1.L expression in embryo decreased amount chrd.1.L expression in the embryo decreased amount hoxa1.L expression in embryo decreased amount hoxb4.L expression in embryo decreased amount otx2.L expression in embryo

Fig.4.I

Gur M et al. (2022)

Xla Wt + bmp4

NF11 (RT-PCR)

Anatomical Phenotype
partially ventralized embryo

Expression Phenotype
decreased amount aldh1a2.L expression in the embryo decreased amount admp.L expression in the embryo decreased amount aldh1a3.L expression in embryo decreased amount gsc.L expression in the embryo increased amount szl.L expression in embryo increased amount ventx1.2.L expression in embryo

Fig.4.I

Gur M et al. (2022)

Xla Wt + bmp4

NF13 (RT-PCR)

Anatomical Phenotype
partially ventralized embryo

Expression Phenotype
decreased amount aldh1a2.L expression in the embryo decreased amount admp.L expression in the embryo decreased amount aldh1a3.L expression in embryo decreased amount gsc.L expression in the embryo decreased amount ventx1.2.L expression in embryo

Fig.7.A

Gur M et al. (2022)

Xla Wt + Retinoic acid

NF12 (RT-PCR)

Expression Phenotype
decreased amount aldh1a2.L expression in the embryo increased amount cyp26a1.L expression in the embryo increased amount dhrs3.L expression in the embryo decreased amount aldh1a3.L expression in embryo decreased amount hoxb1.L expression in embryo decreased amount rdh10.L expression in embryo

Fig.7.C

Gur M et al. (2022)

Xla Wt + Retinoic acid

NF12 (RT-PCR)

Expression Phenotype
increased amount aldh1a2.L expression in embryo increased amount gsc.L expression in the embryo decreased amount hoxa1.L expression in embryo decreased amount hoxb4.L expression in embryo increased amount cer1.L expression in embryo

Fig.4.H

Gur M et al. (2022)

Xla Wt + wnt8a

NF10.25 (RT-PCR)

Anatomical Phenotype
partially dorsalized embryo

Expression Phenotype
increased amount aldh1a2.L expression in embryo increased amount admp.L expression in the embryo increased amount aldh1a3.L expression in the embryo increased amount gsc.L expression in the embryo decreased amount szl.L expression in the embryo decreased amount ventx1.2.L expression in embryo

Fig.4.H

Gur M et al. (2022)

Xla Wt + wnt8a

NF11 (RT-PCR)

Anatomical Phenotype
partially dorsalized embryo

Expression Phenotype
increased amount aldh1a2.L expression in embryo increased amount admp.L expression in the embryo increased amount aldh1a3.L expression in the embryo increased amount gsc.L expression in the embryo decreased amount szl.L expression in the embryo decreased amount ventx1.2.L expression in embryo

Fig.4.H

Gur M et al. (2022)

Xla Wt + wnt8a

NF13 (RT-PCR)

Anatomical Phenotype
partially dorsalized embryo

Expression Phenotype
decreased amount aldh1a2.L expression in the embryo increased amount admp.L expression in the embryo increased amount aldh1a3.L expression in the embryo increased amount gsc.L expression in the embryo decreased amount szl.L expression in the embryo decreased amount ventx1.2.L expression in embryo

fig.4.d

Rankin SA et al. (2012)

Xtr Wt + BMS493

NF35/36 (in situ hybridization)

Expression Phenotype
decreased amount aldh1a2 expression in lateral plate mesoderm decreased amount osr1 expression in foregut decreased amount osr2 expression in foregut decreased amount sox2 expression in foregut decreased amount wnt2b expression in lateral plate mesoderm