congenital heart disease has 6 phenotype(s)
Images Sources Experiment + Assay Phenotypes Human Diseases
Fig. 3 A-H, L, M

Sempou E et al. (2018)
Xtr Wt + fgfr4 CRISPR

NF17 (immunohistochemistry)
Anatomical Phenotype
abnormal gastrocoel roof plate morphology
abnormal left-right organizer morphology
abnormally decreased number of cilium in the left-right organizer
congenital heart disease
visceral heterotaxy
Fig. 3 I-K

Sempou E et al. (2018)
Xtr Wt + fgfr4 CRISPR

NF17 (immunohistochemistry)
Anatomical Phenotype
abnormal gastrocoel roof plate morphology
abnormal left-right organizer morphology
decreased size of the presomitic mesoderm
Expression Phenotype
decreased amount myod1 expression in gastrocoel roof plate
decreased amount myod1 expression in left-right organizer
congenital heart disease
visceral heterotaxy
Fig. S 2 A, B

Sempou E et al. (2018)
Xtr Wt + fgfr4 CRISPR

NF17 (immunohistochemistry)
Anatomical Phenotype
abnormal gastrocoel roof plate morphology
abnormal left-right organizer morphology
abnormally decreased number of cilium in the left-right organizer
Expression Phenotype
decreased amount tuba4b expression in left-right organizer
congenital heart disease
visceral heterotaxy
Fig. 1 B C

Sempou E et al. (2018)
Xtr Wt + fgfr4 CRISPR

NF45 (whole-mount microscopy)
Anatomical Phenotype
abnormal alimentary system morphology
abnormal heart looping
congenital heart disease
visceral heterotaxy
Fig. 1 B C

Sempou E et al. (2018)
Xtr Wt + fgfr4 CRISPR

NF45 (whole-mount microscopy)
Anatomical Phenotype
abnormal alimentary system morphology
abnormal heart looping
congenital heart disease
visceral heterotaxy
Fig. 1 B C

Sempou E et al. (2018)
Xtr Wt + fgfr4 CRISPR

NF45 (whole-mount microscopy)
Anatomical Phenotype
abnormal alimentary system morphology
abnormal heart looping
congenital heart disease
visceral heterotaxy