Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
XB-PHENO-16547

Xtr WT + dyrk1a CRISPR, Willsey HR et al. (2020)

Experiment + Assay: Xtr WT + dyrk1a CRISPR + NF46 (RNA-Seq)
Background: Xtr.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
CRISPR dyrk1a dyrk1a
 NF stage 2 (2-cell) blastomere
Conditions:
Assay Type Assay Stages Antibody
RNA-Seq NF stage 46 to NF stage 46  
Expression Phenotypes (22):
increased amount apoe expression in brain
increased amount aurkb expression in brain
increased amount ccnb1.2 expression in brain
increased amount ccnb2 expression in brain
increased amount cdca7 expression in brain
increased amount cdk1 expression in brain
increased amount cfd expression in brain
increased amount cks1b expression in brain
increased amount colec12 expression in brain
increased amount dlc expression in brain
decreased amount fos expression in brain
decreased amount hoxc6 expression in brain
increased amount ly6g6c expression in brain
decreased amount myl1 expression in brain
decreased amount mylpf expression in brain
decreased amount npas4 expression in brain
decreased amount ocm4.4 expression in brain
increased amount pimreg expression in brain
increased amount rbp4 expression in brain
decreased amount scn2b expression in brain
decreased amount tnni2 expression in brain
decreased amount tnnt3 expression in brain
Source: Fig. 3 B
Article: XB-ART-57038, PubMed