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XB-PHENO-23217

Xla Wt + ctnnb1tm1, McLin VA et al. (2007)

Experiment + Assay: Xla Wt + ctnnb1tm1 + NF35/36 (in situ hybridization)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
mRNA injection Tg(ctnnb1)tm1Rtmn ctnnb1.S
ctnnb1.L
 NF stage 6 (32-cell) blastomere D2.1.1
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 35 and 36  
Expression Phenotypes (5):
mislocalised darmin.L expression in foregut
decreased amount nkx2-1.L expression in lung bud
decreased amount nr1h5.L expression in liver
decreased amount pdx1.L expression in dorsal pancreatic bud
decreased amount pdx1.L expression in ventral pancreatic bud
Source: Fig.1.B
Article: XB-ART-35992, PubMed