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XB-PHENO-23228

Xla Wt + Mmu.lef1-Mmu.ctnnb1-GR + DEX, McLin VA et al. (2007)

Experiment + Assay: Xla Wt + Mmu.lef1-Mmu.ctnnb1-GR + DEX + NF42 (in situ hybridization)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
mRNA injection Tg(Mmu.lef1-Mmu.ctnnb1-GR) ctnnb1.S
ctnnb1.L
 NF stage 6 (32-cell) blastomere D2.1.1
chemical dexamethasone
NF stage 29 and 30 embryo
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 42  
Anatomical Phenotypes: increased size of the liver primordium
Expression Phenotypes (2):
mislocalised hhex.L expression in liver primordium
increased amount hhex.L expression in liver primordium
Source: Fig.2.B
Article: XB-ART-35992, PubMed