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XB-PHENO-23718

Xla Wt + pdx1 MO + ptf1a MO, Afelik S et al. (2006)

Experiment + Assay: Xla Wt + pdx1 MO + ptf1a MO + NF41 (in situ hybridization)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection ptf1a MO3 ptf1a.S
ptf1a.L
 NF stage 4 (8-cell) blastomere
morpholino injection pdx1 MO1 pdx1.L
pdx1.S
 NF stage 4 (8-cell) blastomere
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 41  
Anatomical Phenotypes: abnormal bending of tail
Expression Phenotypes (2):
decreased amount ptf1a.S expression in dorsal pancreatic bud
decreased amount ptf1a.S expression in ventral pancreatic bud
Source: fig.S4.3
Article: XB-ART-261, PubMed