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XB-PHENO-24115

Xla + asxl3 MO, Lichtig H et al. (2020)

Experiment + Assay: Xla + asxl3 MO + NF18 (in situ hybridization)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection asxl3 MO1 asxl3.L
 NF stage 1 whole organism
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 18  
Anatomical Phenotypes: abnormal anterior neural tube morphology , abnormal neural tube closure
Expression Phenotypes (3):
decreased amount tubb2b.L expression in neural tube
decreased amount tubb2b.L expression in Rohon-Beard neuron
decreased amount tubb2b.L expression in trigeminal placode
Source: Fig. 1 B r1c2
Article: XB-ART-56785, PubMed