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XB-PHENO-24166

Xtr Wt + copb1 CRISPR, Macken WL et al. (2021)

Experiment + Assay: Xtr Wt + copb1 CRISPR + NF41 (3D imaging)
Background: Xtr.Nigerian1EXRC
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
CRISPR  
NF stage 1 whole organism
Conditions:
Assay Type Assay Stages Antibody
3D imaging NF stage 41  
Anatomical Phenotypes: abnormal brain morphology , abnormal eye morphology , abnormal forebrain morphology , abnormal head morphology , abnormal lens , decreased size of the chondrocranium , decreased size of the eye , decreased size of the forebrain , decreased size of the hindbrain , decreased size of the midbrain , decreased width of the head
Human Disease Associations: cataract, microcephaly
Source: Fig. 5 FIL
Article: XB-ART-57855, PubMed