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XB-PHENO-24241

Xtr Wt + fgfr4 CRISPR, Sempou E et al. (2018)

Experiment + Assay: Xtr Wt + fgfr4 CRISPR + NF45 (whole-mount microscopy)
Background: Xtr.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
CRISPR fgfr4 gRNA1 fgfr4
 NF stage 1 zygote
Conditions:
Assay Type Assay Stages Antibody
whole-mount microscopy NF stage 45 to NF stage 45  
Anatomical Phenotypes: abnormal alimentary system morphology , abnormal heart looping
Human Disease Associations: congenital heart disease, visceral heterotaxy
Source: Fig. 1 B C
Article: XB-ART-55550, PubMed