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XB-PHENO-25388

Xla Wt + pqbp1 MO, Iwasaki Y and Thomsen GH (2014)

Experiment + Assay: Xla Wt + pqbp1 MO + NF28 (in situ hybridization)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection pqbp1 MO1 pqbp1 (Xla)
 NF stage 3 (4-cell) blastomere
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 28  
Anatomical Phenotypes: decreased length of anterior-posterior axis , decreased size of the head , decreased size of the tail bud
Expression Phenotypes (3):
decreased amount ncam1.L expression in brain
decreased amount ncam1.L expression in nervous system
decreased amount ncam1.L expression in trunk neural crest
Human Disease Associations: Renpenning syndrome
Source: Fig.3.C
Article: XB-ART-49433, PubMed