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XB-PHENO-25899

Xtr WT + TALEN hps6, Nakayama T et al. (2017)

Experiment + Assay: Xtr WT + TALEN hps6 + NF46-47 (whole-mount microscopy)
Background: Xtr.Ivory CoastNXR
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
TALEN hps6
 NF stage 1 whole organism
Conditions:
Assay Type Assay Stages Antibody
whole-mount microscopy NF stage 46 to NF stage 47  
Anatomical Phenotypes: abnormal eye morphology , abnormal inner ear morphology , abnormal intestine morphology , absent iridophore , decreased pigmentation in the epidermis , decreased pigmentation in the eye , decreased pigmentation in the whole organism , decreased size of the eye
Human Disease Associations: visceral heterotaxy, Hermansky-Pudlak syndrome
Source: Fig. 9 B: bcd; C:bcd; D:bc
Article: XB-ART-52468, PubMed