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Profile Publications(102)
XB-PERS-1298

Publications By Hyun-Shik Lee

Results 1 - 50 of 102 results

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A chemical biology route to site-specific authentic protein modifications., Yang A, Ha S, Ahn J, Kim R, Kim S, Lee Y, Kim J, Söll D, Lee HY, Park HS., Science. 354 (6312): 623-626.


Comparative Analysis of the Developmental Toxicity in Xenopus laevis and Danio rerio Induced by Al2 O3 Nanoparticle Exposure., Ismail T, Lee HK, Kim C, Kim Y, Lee H, Kim JH, Kwon S, Huh TL, Khang D, Kim SH, Choi SC, Lee HS., Environ Toxicol Chem. December 1, 2019; 38 (12): 2672-2681.


Peroxiredoxin5 Controls Vertebrate Ciliogenesis by Modulating Mitochondrial Reactive Oxygen Species., Ji Y, Chae S, Lee HK, Park I, Kim C, Ismail T, Kim Y, Park JW, Kwon OS, Kang BS, Lee DS, Bae JS, Kim SH, Moon PG, Baek MC, Park MJ, Kil IS, Rhee SG, Kim J, Huh YH, Shin JY, Min KJ, Kwon TK, Jang DG, Woo HA, Kwon T, Park TJ, Lee HS., Antioxid Redox Signal. May 10, 2019; 30 (14): 1731-1745.  


Dual actions on gout flare and acute kidney injury along with enhanced renal transporter activities by Yokuininto, a Kampo medicine., Lee SH, Lee HS, Park G, Oh SM, Oh DS., BMC Complement Altern Med. March 12, 2019; 19 (1): 57.        


Lysine demethylase 3a in craniofacial and neural development during Xenopus embryogenesis., Lee HK, Ismail T, Kim C, Kim Y, Park JW, Kwon OS, Kang BS, Lee DS, Kwon T, Park TJ, Lee HS., Int J Mol Med. February 1, 2019; 43 (2): 1105-1113.


Inhibitory effects of Kampo medicines, Keishibukuryogan and Shakuyakukanzoto, on the substrate uptake activities of solute carrier organic anion transporters., Lee HS, Shin HJ, Cho M, Lee SH, Oh DS., J Pharmacol Sci. December 1, 2018; 138 (4): 279-283.


Xenopus: An alternative model system for identifying muco-active agents., Sim HJ, Kim SH, Myung KJ, Kwon T, Lee HS, Park TJ., PLoS One. January 1, 2018; 13 (2): e0193310.              


Evaluation of the toxic effects of celecoxib on Xenopus embryo development., Yoon YH, Kim JY, Bae YC, Nam SW, Cho HJ, Lee S, Chung HY, Lee HS, Park MJ., Biochem Biophys Res Commun. January 1, 2018; 501 (2): 329-335.        


Cerebellar α6 -subunit-containing GABAA receptors: a novel therapeutic target for disrupted prepulse inhibition in neuropsychiatric disorders., Chiou LC, Lee HJ, Ernst M, Huang WJ, Chou JF, Chen HL, Mouri A, Chen LC, Treven M, Mamiya T, Fan PC, Knutson DE, Witzigmann C, Cook J, Sieghart W, Nabeshima T., Br J Pharmacol. January 1, 2018; 175 (12): 2414-2427.


ITGBL1 modulates integrin activity to promote cartilage formation and protect against arthritis., Song EK, Jeon J, Jang DG, Kim HE, Sim HJ, Kwon KY, Medina-Ruiz S, Jang HJ, Lee AR, Rho JG, Lee HS, Kim SJ, Park CY, Myung K, Kim W, Kwon T, Yang S, Park TJ., Sci Transl Med. January 1, 2018; 10 (462):   


Physiological effects of KDM5C on neural crest migration and eye formation during vertebrate development., Kim Y, Jeong Y, Kwon K, Ismail T, Lee HK, Kim C, Park JW, Kwon OS, Kang BS, Lee DS, Park TJ, Kwon T, Lee HS., Epigenetics Chromatin. January 1, 2018; 11 (1): 72.


Autoinhibition of Dishevelled protein regulated by its extreme C terminus plays a distinct role in Wnt/β-catenin and Wnt/planar cell polarity (PCP) signaling pathways., Qi J, Lee HJ, Saquet A, Cheng XN, Shao M, Zheng JJ, Shi DL., J Biol Chem. January 1, 2017; 292 (14): 5898-5908.


Novel Molecule Exhibiting Selective Affinity for GABAA Receptor Subtypes., Borghese CM, Herman M, Snell LD, Lawrence KJ, Lee HY, Backos DS, Vanderlinden LA, Harris RA, Roberto M, Hoffman PL, Tabakoff B., Sci Rep. January 1, 2017; 7 (1): 6230.


Peroxiredoxin1, a novel regulator of pronephros development, influences retinoic acid and Wnt signaling by controlling ROS levels., Chae S, Lee HK, Kim YK, Jung Sim H, Ji Y, Kim C, Ismail T, Park JW, Kwon OS, Kang BS, Lee DS, Bae JS, Kim SH, Min KJ, Kyu Kwon T, Park MJ, Han JK, Kwon T, Park TJ, Lee HS., Sci Rep. January 1, 2017; 7 (1): 8874.                    


Structure-Activity Studies of Cysteine-Rich α-Conotoxins that Inhibit High-Voltage-Activated Calcium Channels via GABA(B) Receptor Activation Reveal a Minimal Functional Motif., Carstens BB, Berecki G, Daniel JT, Lee HS, Jackson KA, Tae HS, Sadeghi M, Castro J, O'Donnell T, Deiteren A, Brierley SM, Craik DJ, Adams DJ, Clark RJ., Angew Chem Int Ed Engl. April 4, 2016; 55 (15): 4692-6.


PLD1 regulates Xenopus convergent extension movements by mediating Frizzled7 endocytosis for Wnt/PCP signal activation., Lee H, Lee SJ, Kim GH, Yeo I, Han JK., Dev Biol. March 1, 2016; 411 (1): 38-49.                          


ACT-PRESTO: Rapid and consistent tissue clearing and labeling method for 3-dimensional (3D) imaging., Lee E, Choi J, Jo Y, Kim JY, Jang YJ, Lee HM, Kim SY, Lee HJ, Cho K, Jung N, Hur EM, Jeong SJ, Moon C, Choe Y, Rhyu IJ, Kim H, Sun W., Sci Rep. January 11, 2016; 6 18631.              


TrpA1 Regulates Defecation of Food-Borne Pathogens under the Control of the Duox Pathway., Du EJ, Ahn TJ, Kwon I, Lee JH, Park JH, Park SH, Kang TM, Cho H, Kim TJ, Kim HW, Jun Y, Lee HJ, Lee YS, Kwon JY, Kang K., PLoS Genet. January 1, 2016; 12 (1): e1005773.          


A pharmacological characterization of GABA, THIP and DS2 at binary α4β3 and β3δ receptors: GABA activates β3δ receptors via the β3(+)δ(-) interface., Lee HJ, Absalom NL, Hanrahan JR, van Nieuwenhuijzen P, Ahring PK, Chebib M., Brain Res. January 1, 2016; 1644 222-30.


The splicing factor SRSF1 modulates pattern formation by inhibiting transcription of tissue specific genes during embryogenesis., Lee SH, Lee HK, Kim C, Kim YK, Ismail T, Jeong Y, Park K, Park JW, Kwon OS, Kang BS, Lee DS, Park MJ, Park DS, Lee HS., Biochem Biophys Res Commun. January 1, 2016; 477 (4): 1011-1016.                


Capsaicin inhibits the Wnt/β-catenin signaling pathway by down-regulating PP2A., Park DS, Yoon GH, Lee HS, Choi SC., Biochem Biophys Res Commun. January 1, 2016; 478 (1): 455-461.              


NSrp70 is significant for embryonic growth and development, being a crucial factor for gastrulation and mesoderm induction., Lee SH, Kim C, Lee HK, Kim YK, Ismail T, Jeong Y, Park K, Park MJ, Park DS, Lee HS., Biochem Biophys Res Commun. January 1, 2016; 479 (2): 238-244.        


IFT46 plays crucial roles in craniofacial and cilia development., Park I, Lee HK, Kim C, Ismail T, Kim YK, Park JW, Kwon OS, Kang BS, Lee DS, Park TJ, Park MJ, Choi SC, Lee HS., Biochem Biophys Res Commun. January 1, 2016; 477 (3): 419-25.            


Perfluoroheptanoic acid affects amphibian embryogenesis by inducing the phosphorylation of ERK and JNK., Kim M, Park MS, Son J, Park I, Lee HK, Kim C, Min BH, Ryoo J, Choi KS, Lee DS, Lee HS., Int J Mol Med. December 1, 2015; 36 (6): 1693-700.


Characterization of ticlopidine-induced developmental and teratogenic defects in Xenopus embryos and human endothelial cells., Park MS, Kim JW, Park I, Lee HK, Kim C, Jo C, Kim YK, Min BH, Ryoo J, Lee DS, Bae JS, Kim SH, Ye SK, Park MJ, Lee HS., Chem Biol Interact. October 5, 2015; 240 172-8.


Conformational change of Dishevelled plays a key regulatory role in the Wnt signaling pathways., Lee HJ, Shi DL, Zheng JJ., Elife. August 22, 2015; 4 e08142.                      


Cellular analysis of cleavage-stage chick embryos reveals hidden conservation in vertebrate early development., Nagai H, Sezaki M, Kakiguchi K, Nakaya Y, Lee HC, Ladher R, Sasanami T, Han JY, Yonemura S, Sheng G., Development. April 1, 2015; 142 (7): 1279-86.      


Evaluation of developmental toxicity and teratogenicity of diclofenac using Xenopus embryos., Chae JP, Park MS, Hwang YS, Min BH, Kim SH, Lee HS, Park MJ., Chemosphere. February 1, 2015; 120 52-8.


Neural transcription factors: from embryos to neural stem cells., Lee HK, Lee HS, Moody SA., Mol Cells. October 31, 2014; 37 (10): 705-12.    


Simultaneous rather than ordered cleavage of two sites within the BMP4 prodomain leads to loss of ligand in mice., Tilak A, Nelsen SM, Kim HS, Donley N, McKnite A, Lee H, Christian JL., Development. August 1, 2014; 141 (15): 3062-71.  


Pick1 modulates ephrinB1-induced junctional disassembly through an association with ephrinB1., Son J, Park MS, Park I, Lee HK, Lee SH, Kang B, Min BH, Ryoo J, Lee S, Bae JS, Kim SH, Park MJ, Lee HS., Biochem Biophys Res Commun. July 18, 2014; 450 (1): 659-65.


EphrinB2 affects apical constriction in Xenopus embryos and is regulated by ADAM10 and flotillin-1., Ji YJ, Hwang YS, Mood K, Cho HJ, Lee HS, Winterbottom E, Cousin H, Daar IO., Nat Commun. July 8, 2014; 5 3516.                  


Systematic family-wide analysis of sodium bicarbonate cotransporter NBCn1/SLC4A7 interactions with PDZ scaffold proteins., Lee HJ, Kwon MH, Lee S, Hall RA, Yun CC, Choi I., Physiol Rep. May 1, 2014; 2 (5):           


Esculetin suppresses proliferation of human colon cancer cells by directly targeting β-catenin., Lee SY, Lim TG, Chen H, Jung SK, Lee HJ, Lee MH, Kim DJ, Shin A, Lee KW, Bode AM, Surh YJ, Dong Z., Cancer Prev Res (Phila). December 1, 2013; 6 (12): 1356-64.


Metabolic activation of CaMKII by coenzyme A., McCoy F, Darbandi R, Lee HC, Bharatham K, Moldoveanu T, Grace CR, Dodd K, Lin W, Chen SI, Tangallapally RP, Kurokawa M, Lee RE, Shelat AA, Chen T, Green DR, Harris RA, Lin SH, Fissore RA, Colbran RJ, Nutt LK., Mol Cell. November 7, 2013; 52 (3): 325-39.


In vivo evaluation and comparison of developmental toxicity and teratogenicity of perfluoroalkyl compounds using Xenopus embryos., Kim M, Son J, Park MS, Ji Y, Chae S, Jun C, Bae JS, Kwon TK, Choo YS, Yoon H, Yoon D, Ryoo J, Kim SH, Park MJ, Lee HS., Chemosphere. October 1, 2013; 93 (6): 1153-60.


Multiparametric analysis of CLASP-interacting protein functions during interphase microtubule dynamics., Long JB, Bagonis M, Lowery LA, Lee H, Danuser G, Van Vactor D., Mol Cell Biol. April 1, 2013; 33 (8): 1528-45.


The Smurf ubiquitin ligases regulate tissue separation via antagonistic interactions with ephrinB1., Hwang YS, Lee HS, Kamata T, Mood K, Cho HJ, Winterbottom E, Ji YJ, Singh A, Daar IO., Genes Dev. March 1, 2013; 27 (5): 491-503.                    


Opening the shaker K+ channel with hanatoxin., Milescu M, Lee HC, Bae CH, Kim JI, Swartz KJ., J Gen Physiol. February 1, 2013; 141 (2): 203-16.              


Low nanomolar GABA effects at extrasynaptic α4β1/β3δ GABA(A) receptor subtypes indicate a different binding mode for GABA at these receptors., Karim N, Wellendorph P, Absalom N, Bang LH, Jensen ML, Hansen MM, Lee HJ, Johnston GA, Hanrahan JR, Chebib M., Biochem Pharmacol. August 15, 2012; 84 (4): 549-57.


Mutations in IRX5 impair craniofacial development and germ cell migration via SDF1., Bonnard C, Strobl AC, Shboul M, Lee H, Merriman B, Nelson SF, Ababneh OH, Uz E, Güran T, Kayserili H, Hamamy H, Reversade B., Nat Genet. May 13, 2012; 44 (6): 709-13.    


Analysis of the expression of microtubule plus-end tracking proteins (+TIPs) during Xenopus laevis embryogenesis., Park EC, Lee H, Hong Y, Kim MJ, Lee ZW, Kim SI, Kim S, Kim GH, Han JK., Gene Expr Patterns. May 1, 2012; 12 (5-6): 204-12.                                                              


Bimodal effects of fluoxetine on cerebral nitrergic neurogenic vasodilation in porcine large cerebral arteries., Chen MF, Huang YC, Long C, Yang HI, Lee HC, Chen PY, Hoffer BJ, Lee TJ., Neuropharmacology. March 1, 2012; 62 (4): 1651-8.


Effects of clonidine on the activity of the rat glutamate transporter EAAT3 expressed in Xenopus oocytes., Woo JH, Han JI, Baik HJ, Lee H., Korean J Anesthesiol. March 1, 2012; 62 (3): 266-71.    


Small molecule inhibitors of ezrin inhibit the invasive phenotype of osteosarcoma cells., Bulut G, Hong SH, Chen K, Beauchamp EM, Rahim S, Kosturko GW, Glasgow E, Dakshanamurthy S, Lee HS, Daar I, Toretsky JA, Khanna C, Uren A., Oncogene. January 19, 2012; 31 (3): 269-81.


(1S, 3S)-3-amino-4-difluoromethylenyl-1-cyclopentanoic acid (CPP-115), a potent γ-aminobutyric acid aminotransferase inactivator for the treatment of cocaine addiction., Pan Y, Gerasimov MR, Kvist T, Wellendorph P, Madsen KK, Pera E, Lee H, Schousboe A, Chebib M, Bräuner-Osborne H, Craft CM, Brodie JD, Schiffer WK, Dewey SL, Miller SR, Silverman RB., J Med Chem. January 12, 2012; 55 (1): 357-66.


Using 32-cell stage Xenopus embryos to probe PCP signaling., Lee HS, Sokol SY, Moody SA, Daar IO., Methods Mol Biol. January 1, 2012; 839 91-104.


Inhibition of FGF signaling converts dorsal mesoderm to ventral mesoderm in early Xenopus embryos., Lee SY, Lim SK, Cha SW, Yoon J, Lee SH, Lee HS, Park JB, Lee JY, Kim SC, Kim J., Differentiation. September 1, 2011; 82 (2): 99-107.                    


Dorsal-ventral patterning: Crescent is a dorsally secreted Frizzled-related protein that competitively inhibits Tolloid proteases., Ploper D, Lee HX, De Robertis EM., Dev Biol. April 15, 2011; 352 (2): 317-28.          


EphrinB1 interacts with the transcriptional co-repressor Groucho/xTLE4., Kamata T, Bong YS, Mood K, Park MJ, Nishanian TG, Lee HS., BMB Rep. March 1, 2011; 44 (3): 199-204.

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