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Profile Publications(74)

Publications By Rebecca Heald

Results 1 - 50 of 74 results

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The power of amphibians to elucidate mechanisms of size control and scaling., Miller KE, Brownlee C, Heald R., Exp Cell Res. July 1, 2020; 392 (1): 112036.

The Use of Cell-Free Xenopus Extracts to Investigate Cytoplasmic Events., Gibeaux R, Heald R., Cold Spring Harb Protoc. January 1, 2019; 2019 (6):

Importin α Partitioning to the Plasma Membrane Regulates Intracellular Scaling., Brownlee C, Heald R., Cell. January 1, 2019; 176 (4): 805-815.e8.                  

Generation of Xenopus Haploid, Triploid, and Hybrid Embryos., Gibeaux R, Heald R., Methods Mol Biol. January 1, 2019; 1920 303-315.

Kif2a Scales Meiotic Spindle Size in Hymenochirus boettgeri., Miller KE, Session AM, Heald R., Curr Biol. January 1, 2019; 29 (21): 3720-3727.e5.                  

Paternal chromosome loss and metabolic crisis contribute to hybrid inviability in Xenopus., Gibeaux R, Acker R, Kitaoka M, Georgiou G, van Kruijsbergen I, Ford B, Marcotte EM, Nomura DK, Kwon T, Veenstra GJC, Heald R., Nature. January 1, 2018; 553 (7688): 337-341.      

Preparation of Cellular Extracts from Xenopus Eggs and Embryos., Good MC, Heald R., Cold Spring Harb Protoc. January 1, 2018; 2018 (6):

Subcellular scaling: does size matter for cell division?, Heald R, Gibeaux R., Curr Opin Cell Biol. January 1, 2018; 52 88-95.

Spindle assembly in egg extracts of the Marsabit clawed frog, Xenopus borealis., Kitaoka M, Heald R, Gibeaux R., Cytoskeleton (Hoboken). January 1, 2018; 75 (6): 244-257.

Katanin-like protein Katnal2 is required for ciliogenesis and brain development in Xenopus embryos., Willsey HR, Walentek P, Exner CRT, Xu Y, Lane AB, Harland RM, Heald R, Santama N., Dev Biol. January 1, 2018; 442 (2): 276-287.                                      

Xenopus Hybrids Provide Insight Into Cell and Organism Size Control., Gibeaux R, Miller K, Acker R, Kwon T, Heald R., Front Physiol. January 1, 2018; 9 1758.        

Regulatory remodeling in the allo-tetraploid frog Xenopus laevis., Elurbe DM, Paranjpe SS, Georgiou G, van Kruijsbergen I, Bogdanovic O, Gibeaux R, Heald R, Lister R, Huynen MA, van Heeringen SJ, Veenstra GJC., Genome Biol. January 1, 2017; 18 (1): 198.              

Mitotic noncoding RNA processing promotes kinetochore and spindle assembly in Xenopus., Grenfell AW, Heald R, Strzelecka M., J Cell Biol. July 18, 2016; 214 (2): 133-41.          

A versatile multivariate image analysis pipeline reveals features of Xenopus extract spindles., Grenfell AW, Strzelecka M, Crowder ME, Helmke KJ, Schlaitz AL, Heald R., J Cell Biol. April 11, 2016; 213 (1): 127-36.              

Correction: Mitotic noncoding RNA processing promotes kinetochore and spindle assembly in Xenopus., Grenfell AW, Heald R, Strzelecka M., J Cell Biol. January 1, 2016; 214 (6): 783.

Genome evolution in the allotetraploid frog Xenopus laevis., Session AM, Uno Y, Kwon T, Chapman JA, Toyoda A, Takahashi S, Fukui A, Hikosaka A, Suzuki A, Kondo M, van Heeringen SJ, Quigley I, Heinz S, Ogino H, Ochi H, Hellsten U, Lyons JB, Simakov O, Putnam N, Stites J, Kuroki Y, Tanaka T, Michiue T, Watanabe M, Bogdanovic O, Lister R, Georgiou G, Paranjpe SS, van Kruijsbergen I, Shu S, Carlson J, Kinoshita T, Ohta Y, Mawaribuchi S, Jenkins J, Grimwood J, Schmutz J, Mitros T, Mozaffari SV, Suzuki Y, Haramoto Y, Yamamoto TS, Takagi C, Heald R, Miller K, Haudenschild C, Kitzman J, Nakayama T, Izutsu Y, Robert J, Fortriede J, Burns K, Lotay V, Karimi K, Yasuoka Y, Dichmann DS, Flajnik MF, Houston DW, Shendure J, DuPasquier L, Vize PD, Zorn AM, Ito M, Marcotte EM, Wallingford JB, Ito Y, Asashima M, Ueno N, Matsuda Y, Veenstra GJ, Fujiyama A, Harland RM, Taira M, Rokhsar DS., Nature. January 1, 2016; 538 (7625): 336-343.                              

Enzymatically Generated CRISPR Libraries for Genome Labeling and Screening., Lane AB, Strzelecka M, Ettinger A, Grenfell AW, Wittmann T, Heald R., Dev Cell. August 10, 2015; 34 (3): 373-8.        

Biological Scaling Problems and Solutions in Amphibians., Levy DL, Heald R., Cold Spring Harb Perspect Biol. August 10, 2015; 8 (1): a019166.

A comparative analysis of spindle morphometrics across metazoans., Crowder ME, Strzelecka M, Wilbur JD, Good MC, von Dassow G, Heald R., Curr Biol. June 1, 2015; 25 (11): 1542-50.

Glutamylation of Nap1 modulates histone H1 dynamics and chromosome condensation in Xenopus., Miller KE, Heald R., J Cell Biol. April 27, 2015; 209 (2): 211-20.          

TPX2 levels modulate meiotic spindle size and architecture in Xenopus egg extracts., Helmke KJ, Heald R., J Cell Biol. August 4, 2014; 206 (3): 385-93.          

Cytoplasmic volume modulates spindle size during embryogenesis., Good MC, Vahey MD, Skandarajah A, Fletcher DA, Heald R., Science. November 15, 2013; 342 (6160): 856-60.

Mitotic spindle scaling during Xenopus development by kif2a and importin α., Wilbur JD, Heald R., Elife. February 19, 2013; 2 e00290.                  

N-terminal phosphorylation of p60 katanin directly regulates microtubule severing., Whitehead E, Heald R, Wilbur JD., J Mol Biol. January 23, 2013; 425 (2): 214-21.

Histone H1 compacts DNA under force and during chromatin assembly., Xiao B, Freedman BS, Miller KE, Heald R, Marko JF., Mol Biol Cell. December 1, 2012; 23 (24): 4864-71.        

Altering membrane topology with Sar1 does not impair spindle assembly in Xenopus egg extracts., Riggs B, Bergman ZJ, Heald R., Cytoskeleton (Hoboken). August 1, 2012; 69 (8): 591-9.

Multiple domains of human CLASP contribute to microtubule dynamics and organization in vitro and in Xenopus egg extracts., Patel K, Nogales E, Heald R., Cytoskeleton (Hoboken). March 1, 2012; 69 (3): 155-65.              

Mechanisms of intracellular scaling., Levy DL, Heald R., Annu Rev Cell Dev Biol. January 1, 2012; 28 113-35.

Katanin contributes to interspecies spindle length scaling in Xenopus., Loughlin R, Wilbur JD, McNally FJ, Nédélec FJ, Heald R., Cell. December 9, 2011; 147 (6): 1397-407.

Mitotic spindle assembly around RCC1-coated beads in Xenopus egg extracts., Halpin D, Kalab P, Wang J, Weis K, Heald R., PLoS Biol. December 1, 2011; 9 (12): e1001225.        

Mitotic chromosome size scaling in Xenopus., Kieserman EK, Heald R., Cell Cycle. November 15, 2011; 10 (22): 3863-70.

Importazole, a small molecule inhibitor of the transport receptor importin-β., Soderholm JF, Bird SL, Kalab P, Sampathkumar Y, Hasegawa K, Uehara-Bingen M, Weis K, Heald R., ACS Chem Biol. July 15, 2011; 6 (7): 700-8.

Atomic force microscope imaging of chromatin assembled in Xenopus laevis egg extract., Fu H, Freedman BS, Lim CT, Heald R, Yan J., Chromosoma. June 1, 2011; 120 (3): 245-54.

A computational model predicts Xenopus meiotic spindle organization., Loughlin R, Heald R, Nédélec F., J Cell Biol. December 27, 2010; 191 (7): 1239-49.        

Nuclear size is regulated by importin α and Ntf2 in Xenopus., Levy DL, Heald R., Cell. October 15, 2010; 143 (2): 288-98.          

Xenopus egg extracts increase dynamics of histone H1 on sperm chromatin., Freedman BS, Miller KE, Heald R., PLoS One. September 29, 2010; 5 (9):           

Rebecca Heald., Heald R., Curr Biol. June 22, 2010; 20 (12): R503-4.

Functional comparison of H1 histones in Xenopus reveals isoform-specific regulation by Cdk1 and RanGTP., Freedman BS, Heald R., Curr Biol. June 8, 2010; 20 (11): 1048-52.

Centrosome proteins form an insoluble perinuclear matrix during muscle cell differentiation., Srsen V, Fant X, Heald R, Rabouille C, Merdes A., BMC Cell Biol. April 13, 2009; 10 28.            

Discovery of selective aminothiazole aurora kinase inhibitors., Andersen CB, Wan Y, Chang JW, Riggs B, Lee C, Liu Y, Sessa F, Villa F, Kwiatkowski N, Suzuki M, Nallan L, Heald R, Musacchio A, Gray NS., ACS Chem Biol. March 20, 2008; 3 (3): 180-92.

Mechanisms of mitotic spindle assembly and function., Walczak CE, Heald R., Int Rev Cytol. January 1, 2008; 265 111-58.

Genome-wide analysis demonstrates conserved localization of messenger RNAs to mitotic microtubules., Blower MD, Feric E, Weis K, Heald R., J Cell Biol. December 31, 2007; 179 (7): 1365-73.          

Xenopus tropicalis egg extracts provide insight into scaling of the mitotic spindle., Brown KS, Blower MD, Maresca TJ, Grammer TC, Harland RM, Heald R., J Cell Biol. March 12, 2007; 176 (6): 765-70.        

Micromanipulation studies of chromatin fibers in Xenopus egg extracts reveal ATP-dependent chromatin assembly dynamics., Yan J, Maresca TJ, Skoko D, Adams CD, Xiao B, Christensen MO, Heald R, Marko JF., Mol Biol Cell. February 1, 2007; 18 (2): 464-74.

Essential roles for cohesin in kinetochore and spindle function in Xenopus egg extracts., Deehan Kenney R, Heald R., J Cell Sci. December 15, 2006; 119 (Pt 24): 5057-66.

Analysis of a RanGTP-regulated gradient in mitotic somatic cells., Kaláb P, Pralle A, Isacoff EY, Heald R, Weis K., Nature. March 30, 2006; 440 (7084): 697-701.

The long and the short of it: linker histone H1 is required for metaphase chromosome compaction., Maresca TJ, Heald R., Cell Cycle. March 1, 2006; 5 (6): 589-91.

Xorbit/CLASP links dynamic microtubules to chromosomes in the Xenopus meiotic spindle., Hannak E, Heald R., J Cell Biol. January 2, 2006; 172 (1): 19-25.          

Methods for studying spindle assembly and chromosome condensation in Xenopus egg extracts., Maresca TJ, Heald R., Methods Mol Biol. January 1, 2006; 322 459-74.

Analysis of microtubule polymerization in vitro and during the cell cycle in Xenopus egg extracts., Budde PP, Desai A, Heald R., Methods. January 1, 2006; 38 (1): 29-34.

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