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Profile Publications(97)

Publications By HongYan Zhang

Results 1 - 50 of 97 results

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Structures of mammalian GLD-2 proteins reveal molecular basis of their functional diversity in mRNA and microRNA processing., Ma XY, Zhang H, Feng JX, Hu JL, Yu B, Luo L, Cao YL, Liao S, Wang J, Gao S., Nucleic Acids Res. September 4, 2020; 48 (15): 8782-8795.              

The critical role of dysregulated Hh-FOXM1-TPX2 signaling in human hepatocellular carcinoma cell proliferation., Wang Y, Wang H, Yan Z, Li G, Hu G, Zhang H, Huang D, Wang Y, Zhang X, Yan Y, Lu Q, Cheng M, Luo S., Cell Commun Signal. July 28, 2020; 18 (1): 116.              

Tumor-Suppressive MicroRNA-216b Binds to TPX2, Activating the p53 Signaling in Human Cutaneous Squamous Cell Carcinoma., Feng C, Zhang HL, Zeng A, Bai M, Wang XJ., Mol Ther Nucleic Acids. June 5, 2020; 20 186-195.            

Ectopic expression of a rice plasma membrane intrinsic protein (OsPIP1;3) promotes plant growth and water uptake., Liu S, Fukumoto T, Gena P, Feng P, Sun Q, Li Q, Matsumoto T, Kaneko T, Zhang H, Zhang Y, Zhong S, Zeng W, Katsuhara M, Kitagawa Y, Wang A, Calamita G, Ding X., Plant J. January 1, 2020; 102 (4): 779-796.

The connexin26 human mutation N14K disrupts cytosolic intersubunit interactions and promotes channel opening., Valdez Capuccino JM, Chatterjee P, García IE, Botello-Smith WM, Zhang H, Harris AL, Luo Y, Contreras JE., J Gen Physiol. January 1, 2019; 151 (3): 328-341.

TPX2 level correlates with cholangiocarcinoma cell proliferation, apoptosis, and EMT., Zou Z, Zheng B, Li J, Lv X, Zhang H, Yu F, Kong L, Li Y, Yu M, Fang L, Liang B., Biomed Pharmacother. November 1, 2018; 107 1286-1293.

Understanding the Molecular Basis of Salt Sequestration in Epidermal Bladder Cells of Chenopodium quinoa., Böhm J, Messerer M, Müller HM, Scholz-Starke J, Gradogna A, Scherzer S, Maierhofer T, Bazihizina N, Zhang H, Stigloher C, Ache P, Al-Rasheid KAS, Mayer KFX, Shabala S, Carpaneto A, Haberer G, Zhu JK, Hedrich R., Curr Biol. January 1, 2018; 28 (19): 3075-3085.e7.

Targeting TPX2 suppresses proliferation and promotes apoptosis via repression of the PI3k/AKT/P21 signaling pathway and activation of p53 pathway in breast cancer., Chen M, Zhang H, Zhang G, Zhong A, Ma Q, Kai J, Tong Y, Xie S, Wang Y, Zheng H, Guo L, Lu R., Biochem Biophys Res Commun. January 1, 2018; 507 (1-4): 74-82.          

Control of Xenopus Tadpole Locomotion via Selective Expression of Ih in Excitatory Interneurons., Picton LD, Sillar KT, Zhang HY., Curr Biol. January 1, 2018; 28 (24): 3911-3923.e2.              

Novel mutations involving βI-, βIIA-, or βIVB-tubulin isotypes with functional resemblance to βIII-tubulin in breast cancer., Wang W, Zhang H, Wang X, Patterson J, Winter P, Graham K, Ghosh S, Lee JC, Katsetos CD, Mackey JR, Tuszynski JA, Wong GK, Ludueña RF., Protoplasma. May 1, 2017; 254 (3): 1163-1173.

Pharmacological characterization of the excitatory ''Cys-loop'' GABA receptor family in Caenorhabditis elegans., Nicholl GC, Jawad AK, Weymouth R, Zhang H, Beg AA., Br J Pharmacol. January 1, 2017; 174 (9): 781-795.

Sodium pump regulation of locomotor control circuits., Picton LD, Zhang H, Sillar KT., J Neurophysiol. January 1, 2017; 118 (2): 1070-1081.

Dissecting structures and functions of SecA-only protein-conducting channels: ATPase, pore structure, ion channel activity, protein translocation, and interaction with SecYEG/SecDF•YajC., Hsieh YH, Huang YJ, Zhang H, Liu Q, Lu Y, Yang H, Houghton J, Jiang C, Sui SF, Tai PC., PLoS One. January 1, 2017; 12 (6): e0178307.              

Preclinical Characterization of (R)-3-((3S,4S)-3-fluoro-4-(4-hydroxyphenyl)piperidin-1-yl)-1-(4-methylbenzyl)pyrrolidin-2-one (BMS-986169), a Novel, Intravenous, Glutamate N-Methyl-d-Aspartate 2B Receptor Negative Allosteric Modulator with Potential in Major Depressive Disorder., Bristow LJ, Gulia J, Weed MR, Srikumar BN, Li YW, Graef JD, Naidu PS, Sanmathi C, Aher J, Bastia T, Paschapur M, Kalidindi N, Kumar KV, Molski T, Pieschl R, Fernandes A, Brown JM, Sivarao DV, Newberry K, Bookbinder M, Polino J, Keavy D, Newton A, Shields E, Simmermacher J, Kempson J, Li J, Zhang H, Mathur A, Kallem RR, Sinha M, Ramarao M, Vikramadithyan RK, Thangathirupathy S, Warrier J, Islam I, Bronson JJ, Olson RE, Macor JE, Albright CF, King D, Thompson LA, Marcin LR, Sinz M., J Pharmacol Exp Ther. January 1, 2017; 363 (3): 377-393.

The insecticidal activity and action mode of an imidacloprid analogue, 1-(3-pyridylmethyl)-2-nitroimino-imidazolidine., Zhuang AX, Zhang YX, Zhang H, Liu ZW., Insect Sci. October 1, 2016; 23 (5): 688-94.

Functional identification of a GORK potassium channel from the ancient desert shrub Ammopiptanthus mongolicus (Maxim.) Cheng f., Li J, Zhang H, Lei H, Jin M, Yue G, Su Y., Plant Cell Rep. April 1, 2016; 35 (4): 803-15.

Three pairs of weak interactions precisely regulate the G-loop gate of Kir2.1 channel., Li J, Xiao S, Xie X, Zhou H, Pang C, Li S, Zhang H, Logothetis DE, Zhan Y, An H., Proteins. January 1, 2016; 84 (12): 1929-1937.

Structural Basis for Differences in Dynamics Induced by Leu Versus Ile Residues in the CD Loop of Kir Channels., Lü S, An H, Zhang H, Long M., Mol Neurobiol. January 1, 2016; 53 (9): 5948-5961.

Ikarisoside A inhibits acetylcholine-induced catecholamine secretion and synthesis by suppressing nicotinic acetylcholine receptor-ion channels in cultured bovine adrenal medullary cells., Li X, Toyohira Y, Horisita T, Satoh N, Takahashi K, Zhang H, Iinuma M, Yoshinaga Y, Ueno S, Tsutsui M, Sata T, Yanagihara N., Naunyn Schmiedebergs Arch Pharmacol. December 1, 2015; 388 (12): 1259-69.

Mechanisms underlying the activity-dependent regulation of locomotor network performance by the Na+ pump., Zhang HY, Picton L, Li WC, Sillar KT., Sci Rep. November 6, 2015; 5 16188.                  

TPX2 as a novel prognostic biomarker for hepatocellular carcinoma., Liu Q, Tu K, Zhang H, Zheng X, Yao Y, Liu Q., Hepatol Res. August 1, 2015; 45 (8): 906-18.

Positive Surgical Margin, HPV Persistence, and Expression of Both TPX2 and PD-L1 Are Associated with Persistence/Recurrence of Cervical Intraepithelial Neoplasia after Cervical Conization., Zhang H, Zhang T, You Z, Zhang Y., PLoS One. January 1, 2015; 10 (12): e0142868.  

A DTX/MATE-type transporter facilitates abscisic acid efflux and modulates ABA sensitivity and drought tolerance in Arabidopsis., Zhang H, Zhu H, Pan Y, Yu Y, Luan S, Li L., Mol Plant. October 1, 2014; 7 (10): 1522-32.

Voltage-dependent blockade by bupivacaine of cardiac sodium channels expressed in Xenopus oocytes., Zhang H, Ji H, Liu Z, Ji Y, You X, Ding G, Cheng Z., Neurosci Bull. August 1, 2014; 30 (4): 697-710.

TPX2 knockdown suppressed hepatocellular carcinoma cell invasion via inactivating AKT signaling and inhibiting MMP2 and MMP9 expression., Liu Q, Yang P, Tu K, Zhang H, Zheng X, Yao Y, Liu Q., Chin J Cancer Res. August 1, 2014; 26 (4): 410-7.

Brassica oleracea MATE encodes a citrate transporter and enhances aluminum tolerance in Arabidopsis thaliana., Wu X, Li R, Shi J, Wang J, Sun Q, Zhang H, Xing Y, Qi Y, Zhang N, Guo YD., Plant Cell Physiol. August 1, 2014; 55 (8): 1426-36.

The generation of antiphase oscillations and synchrony by a rebound-based vertebrate central pattern generator., Li WC, Merrison-Hort R, Zhang HY, Borisyuk R., J Neurosci. April 23, 2014; 34 (17): 6065-77.

Lack of negatively charged residues at the external mouth of Kir2.2 channels enable the voltage-dependent block by external Mg2+., Li J, Xie X, Liu J, Yu H, Zhang S, Zhan Y, Zhang H, Logothetis DE, An H., PLoS One. January 1, 2014; 9 (10): e111372.            

G protein-coupled receptor signaling to Kir channels in Xenopus oocytes., Hatcher-Solis C, Fribourg M, Spyridaki K, Younkin J, Ellaithy A, Xiang G, Liapakis G, Gonzalez-Maeso J, Zhang H, Cui M, Logothetis DE., Curr Pharm Biotechnol. January 1, 2014; 15 (10): 987-95.

Specificity of SecYEG for PhoA precursors and SecA homologs on SecA protein-conducting channels., Zhang H, Hsieh YH, Lin BR, Yu L, Yang H, Jiang C, Sui SF, Tai PC., Biochem Biophys Res Commun. July 26, 2013; 437 (2): 212-216.

Reconstitution of functionally efficient SecA-dependent protein-conducting channels: transformation of low-affinity SecA-liposome channels to high-affinity SecA-SecYEG-SecDF·YajC channels., Hsieh YH, Zhang H, Wang H, Yang H, Jiang C, Sui SF, Tai PC., Biochem Biophys Res Commun. February 15, 2013; 431 (3): 388-92.

Two-electrode voltage clamp., Guan B, Chen X, Zhang H., Methods Mol Biol. January 1, 2013; 998 79-89.

Maternal Mga is required for Wnt signaling and organizer formation in the early Xenopus embryo., Gu F, Shi H, Gao L, Zhang H, Tao Q., Acta Biochim Biophys Sin (Shanghai). November 1, 2012; 44 (11): 939-47.

High mobility group B proteins regulate mesoderm formation and dorsoventral patterning during zebrafish and Xenopus early development., Cao JM, Li SQ, Zhang HW, Shi DL., Mech Dev. September 1, 2012; 129 (9-12): 263-74.    

Short-term memory of motor network performance via activity-dependent potentiation of Na+/K+ pump function., Zhang HY, Sillar KT., Curr Biol. March 20, 2012; 22 (6): 526-31.

sizzled function and secreted factor network dynamics., Shi J, Zhang H, Dowell RD, Klymkowsky MW., Biol Open. March 15, 2012; 1 (3): 286-94.            

SecA alone can promote protein translocation and ion channel activity: SecYEG increases efficiency and signal peptide specificity., Hsieh YH, Zhang H, Lin BR, Cui N, Na B, Yang H, Jiang C, Sui SF, Tai PC., J Biol Chem. December 30, 2011; 286 (52): 44702-9.

Membrane depolarization increases membrane PtdIns(4,5)P2 levels through mechanisms involving PKC βII and PI4 kinase., Chen X, Zhang X, Jia C, Xu J, Gao H, Zhang G, Du X, Zhang H., J Biol Chem. November 18, 2011; 286 (46): 39760-7.

Development of a spinal locomotor rheostat., Zhang HY, Issberner J, Sillar KT., Proc Natl Acad Sci U S A. July 12, 2011; 108 (28): 11674-9.  

Puerarin: a novel antagonist to inward rectifier potassium channel (IK1)., Zhang H, Zhang L, Zhang Q, Yang X, Yu J, Shun S, Wu Y, Zeng Q, Wang T., Mol Cell Biochem. June 1, 2011; 352 (1-2): 117-23.

Mechanism of acetylcholine receptor cluster formation induced by DC electric field., Zhang HL, Peng HB., PLoS One. January 1, 2011; 6 (10): e26805.                    

Dual effects of nobiletin, a citrus polymethoxy flavone, on catecholamine secretion in cultured bovine adrenal medullary cells., Zhang H, Toyohira Y, Ueno S, Shinohara Y, Itoh H, Furuno Y, Yamakuni T, Tsutsui M, Takahashi K, Yanagihara N., J Neurochem. August 1, 2010; 114 (4): 1030-8.

Depolarization increases phosphatidylinositol (PI) 4,5-bisphosphate level and KCNQ currents through PI 4-kinase mechanisms., Zhang X, Chen X, Jia C, Geng X, Du X, Zhang H., J Biol Chem. March 26, 2010; 285 (13): 9402-9.

5-Stabilized phosphatidylinositol 3,4,5-trisphosphate analogues bind Grp1 PH, inhibit phosphoinositide phosphatases, and block neutrophil migration., Zhang H, He J, Kutateladze TG, Sakai T, Sasaki T, Markadieu N, Erneux C, Prestwich GD., Chembiochem. February 15, 2010; 11 (3): 388-95.

Electrical coupling synchronises spinal motoneuron activity during swimming in hatchling Xenopus tadpoles., Zhang HY, Li WC, Heitler WJ, Sillar KT., J Physiol. September 15, 2009; 587 (Pt 18): 4455-66.

The formation of acetylcholine receptor clusters visualized with quantum dots., Geng L, Zhang HL, Peng HB., BMC Neurosci. July 16, 2009; 10 80.              

Specificity of Gbetagamma signaling depends on Galpha subunit coupling with G-protein-sensitive K(+) channels., Geng X, Du XN, Rusinova R, Liu BY, Li F, Zhang X, Chen XJ, Logothetis DE, Zhang HL., Pharmacology. January 1, 2009; 84 (2): 82-90.

Correlations between clinical and physiological consequences of the novel mutation R878C in a highly conserved pore residue in the cardiac Na+ channel., Zhang Y, Wang T, Ma A, Zhou X, Gui J, Wan H, Shi R, Huang C, Grace AA, Huang CL, Trump D, Zhang H, Zimmer T, Lei M., Acta Physiol (Oxf). December 1, 2008; 194 (4): 311-23.            

Antibody microarray analyses of signal transduction protein expression and phosphorylation during porcine oocyte maturation., Pelech S, Jelinkova L, Susor A, Zhang H, Shi X, Pavlok A, Kubelka M, Kovarova H., J Proteome Res. July 1, 2008; 7 (7): 2860-71.

Molecular basis for genistein-induced inhibition of Kir2.3 currents., Zhao Z, Liu B, Zhang G, Jia Z, Jia Q, Geng X, Zhang H., Pflugers Arch. May 1, 2008; 456 (2): 413-23.

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