Results 1 - 50 of 175 results
A Brief History of Xenopus in Biology. , De Robertis EM , Gurdon JB ., Cold Spring Harb Protoc. March 30, 2021;
GSK3 Inhibits Macropinocytosis and Lysosomal Activity through the Wnt Destruction Complex Machinery. , Albrecht LV, Tejeda-Muñoz N, Bui MH, Cicchetto AC, Di Biagio D, Colozza G , Schmid E, Piccolo S , Christofk HR, De Robertis EM ., Cell Rep. January 1, 2020; 32 (4): 107973.
Dact-4 is a Xenopus laevis Spemann organizer gene related to the Dapper/Frodo antagonist of β-catenin family of proteins. , Colozza G , De Robertis EM ., Gene Expr Patterns. January 1, 2020; 38 119153.
Wnt-inducible Lrp6- APEX2 interacting proteins identify ESCRT machinery and Trk-fused gene as components of the Wnt signaling pathway. , Colozza G , Jami-Alahmadi Y, Dsouza A, Tejeda-Muñoz N, Albrecht LV, Sosa EA, Wohlschlegel JA, De Robertis EM ., Sci Rep. January 1, 2020; 10 (1): 21555.
Transcriptome analysis of regeneration during Xenopus laevis experimental twinning. , Sosa EA, Moriyama Y , Ding Y , Tejeda-Muñoz N, Colozza G , De Robertis EM ., Int J Dev Biol. January 1, 2019; 63 (6-7): 301-309.
Embryonic regeneration by relocalization of the Spemann organizer during twinning in Xenopus. , Moriyama Y , De Robertis EM ., Proc Natl Acad Sci U S A. January 1, 2018; 115 (21): E4815-E4822.
Bighead is a Wnt antagonist secreted by the Xenopus Spemann organizer that promotes Lrp6 endocytosis. , Ding Y , Colozza G , Sosa EA, Moriyama Y , Rundle S, Salwinski L, De Robertis EM ., Proc Natl Acad Sci U S A. January 1, 2018; 115 (39): E9135-E9144.
Generation of animal form by the Chordin/Tolloid/BMP gradient: 100 years after D''Arcy Thompson. , De Robertis EM , Moriyama Y , Colozza G ., Dev Growth Differ. September 1, 2017; 59 (7): 580-592.
Genome-wide analysis of dorsal and ventral transcriptomes of the Xenopus laevis gastrula. , Ding Y , Colozza G , Zhang K, Moriyama Y , Ploper D, Sosa EA, Benitez MDJ, De Robertis EM ., Dev Biol. January 1, 2017; 426 (2): 176-187.
Spemann organizer transcriptome induction by early beta-catenin, Wnt, Nodal, and Siamois signals in Xenopus laevis. , Ding Y , Ploper D, Sosa EA, Colozza G , Moriyama Y , Benitez MD, Zhang K, Merkurjev D, De Robertis EM ., Proc Natl Acad Sci U S A. January 1, 2017; 114 (15): E3081-E3090.
Angiopoietin-like 4 Is a Wnt Signaling Antagonist that Promotes LRP6 Turnover. , Kirsch N, Chang LS, Koch S, Glinka A , Dolde C, Colozza G , Benitez MDJ, De Robertis EM , Niehrs C ., Dev Cell. January 1, 2017; 43 (1): 71-82.e6.
The Chordin Morphogenetic Pathway. , De Robertis EM , Moriyama Y ., Curr Top Dev Biol. January 1, 2016; 116 231-45.
Morpholinos: Antisense and Sensibility. , Blum M , De Robertis EM , Wallingford JB , Niehrs C ., Dev Cell. October 26, 2015; 35 (2): 145-9.
EMBRYO DEVELOPMENT. BMP gradients: A paradigm for morphogen-mediated developmental patterning. , Bier E, De Robertis EM ., Science. June 26, 2015; 348 (6242): aaa5838.
The tumor suppressor Smad4/ DPC4 is regulated by phosphorylations that integrate FGF, Wnt, and TGF-β signaling. , Demagny H, Araki T, De Robertis EM ., Cell Rep. October 23, 2014; 9 (2): 688-700.
Maternal syntabulin is required for dorsal axis formation and is a germ plasm component in Xenopus. , Colozza G , De Robertis EM ., Differentiation. July 1, 2014; 88 (1): 17-26.
Lessons from a great developmental biologist. , De Robertis EM ., Differentiation. July 1, 2014; 88 (1): 3-8.
Herbert Steinbeisser: a life with the Xenopus embryo. , De Robertis EM , Niehrs C ., Int J Dev Biol. January 1, 2014; 58 (5): 299-302.
Chordin forms a self-organizing morphogen gradient in the extracellular space between ectoderm and mesoderm in the Xenopus embryo. , Plouhinec JL, Zakin L, Moriyama Y , De Robertis EM ., Proc Natl Acad Sci U S A. December 17, 2013; 110 (51): 20372-9.
Development: scaling to size by protease inhibition. , De Robertis EM , Colozza G ., Curr Biol. August 5, 2013; 23 (15): R652-4.
Systems control of BMP morphogen flow in vertebrate embryos. , Plouhinec JL, Zakin L, De Robertis EM ., Curr Opin Genet Dev. December 1, 2011; 21 (6): 696-703.
Dorsal- ventral patterning: Crescent is a dorsally secreted Frizzled-related protein that competitively inhibits Tolloid proteases. , Ploper D, Lee HX , De Robertis EM ., Dev Biol. April 15, 2011; 352 (2): 317-28.
Wnt signaling requires sequestration of glycogen synthase kinase 3 inside multivesicular endosomes. , Taelman VF, Dobrowolski R, Plouhinec JL, Fuentealba LC , Vorwald PP, Gumper I, Sabatini DD, De Robertis EM ., Cell. December 23, 2010; 143 (7): 1136-48.
The RNA-binding protein bicaudal C regulates polycystin 2 in the kidney by antagonizing miR-17 activity. , Tran U , Zakin L, Schweickert A , Agrawal R , Döger R, Blum M , De Robertis EM , Wessely O ., Development. April 1, 2010; 137 (7): 1107-16.
Spemann''s organizer and the self-regulation of embryonic fields. , De Robertis EM ., Mech Dev. December 1, 2009; 126 (11-12): 925-41.
Enzymatic regulation of pattern: BMP4 binds CUB domains of Tolloids and inhibits proteinase activity. , Lee HX , Mendes FA, Plouhinec JL, De Robertis EM ., Genes Dev. November 1, 2009; 23 (21): 2551-62.
Mad is required for wingless signaling in wing development and segment patterning in Drosophila. , Eivers E, Fuentealba LC , Sander V, Clemens JC, Hartnett L, De Robertis EM ., PLoS One. August 6, 2009; 4 (8): e6543.
Systems biology of the self-regulating morphogenetic gradient of the Xenopus gastrula. , Plouhinec JL, De Robertis EM ., Cold Spring Harb Perspect Biol. August 1, 2009; 1 (2): a001701.
Development of the vertebral morphogenetic field in the mouse: interactions between Crossveinless-2 and Twisted Gastrulation. , Zakin L, Metzinger CA, Chang EY, Coffinier C, De Robertis EM ., Dev Biol. November 1, 2008; 323 (1): 6-18.
Integrating positional information at the level of Smad1/5/8. , Eivers E, Fuentealba LC , De Robertis EM ., Curr Opin Genet Dev. August 1, 2008; 18 (4): 304-10.
Crossveinless-2 Is a BMP feedback inhibitor that binds Chordin/BMP to regulate Xenopus embryonic patterning. , Ambrosio AL, Taelman VF, Lee HX , Metzinger CA, Coffinier C, De Robertis EM ., Dev Cell. August 1, 2008; 15 (2): 248-60.
Expression of Siamois and Twin in the blastula Chordin/ Noggin signaling center is required for brain formation in Xenopus laevis embryos. , Ishibashi H, Matsumura N, Hanafusa H , Matsumoto K , De Robertis EM , Kuroda H ., Mech Dev. January 1, 2008; 125 (1-2): 58-66.
Integrating patterning signals: Wnt/ GSK3 regulates the duration of the BMP/ Smad1 signal. , Fuentealba LC , Eivers E, Ikeda A, Hurtado C, Kuroda H , Pera EM , De Robertis EM ., Cell. November 30, 2007; 131 (5): 980-93.
Neural induction in the absence of organizer in salamanders is mediated by MAPK. , Hurtado C, De Robertis EM ., Dev Biol. July 15, 2007; 307 (2): 282-9.
Systems biology of embryonic morphogens. , Plouhinec JL, De Robertis EM ., Mol Biosyst. July 1, 2007; 3 (7): 454-7.
The opposing homeobox genes Goosecoid and Vent1/2 self-regulate Xenopus patterning. , Sander V, Reversade B , De Robertis EM ., EMBO J. June 20, 2007; 26 (12): 2955-65.
Embryonic dorsal- ventral signaling: secreted frizzled-related proteins as inhibitors of tolloid proteinases. , Lee HX , Ambrosio AL, Reversade B , De Robertis EM ., Cell. January 13, 2006; 124 (1): 147-59.
Regulation of ADMP and BMP2/4/7 at opposite embryonic poles generates a self-regulating morphogenetic field. , Reversade B , De Robertis EM ., Cell. December 16, 2005; 123 (6): 1147-60.
Depletion of Bmp2, Bmp4, Bmp7 and Spemann organizer signals induces massive brain formation in Xenopus embryos. , Reversade B , Kuroda H , Lee H , Mays A, De Robertis EM ., Development. August 1, 2005; 132 (15): 3381-92.
xBtg-x regulates Wnt/beta-Catenin signaling during early Xenopus development. , Wessely O , Kim JI , Tran U , Fuentealba L , De Robertis EM ., Dev Biol. July 1, 2005; 283 (1): 17-28.
Default neural induction: neuralization of dissociated Xenopus cells is mediated by Ras/ MAPK activation. , Kuroda H , Fuentealba L , Ikeda A, Reversade B , De Robertis EM ., Genes Dev. May 1, 2005; 19 (9): 1022-7.
Sirenomelia in Bmp7 and Tsg compound mutant mice: requirement for Bmp signaling in the development of ventral posterior mesoderm. , Zakin L, Reversade B , Kuroda H , Lyons KM, De Robertis EM ., Development. May 1, 2005; 132 (10): 2489-99.
Exploration of the extracellular space by a large-scale secretion screen in the early Xenopus embryo. , Pera EM , Hou S, Strate I, Wessely O , De Robertis EM ., Int J Dev Biol. January 1, 2005; 49 (7): 781-96.
Paraxial protocadherin coordinates cell polarity during convergent extension via Rho A and JNK. , Unterseher F, Hefele JA, Giehl K, De Robertis EM , Wedlich D , Schambony A ., EMBO J. August 18, 2004; 23 (16): 3259-69.
Analysis of Spemann organizer formation in Xenopus embryos by cDNA macroarrays. , Wessely O , Kim JI , Geissert D, Tran U , De Robertis EM ., Dev Biol. May 15, 2004; 269 (2): 552-66.
Neural induction in Xenopus: requirement for ectodermal and endomesodermal signals via Chordin, Noggin, beta-Catenin, and Cerberus. , Kuroda H , Wessely O , De Robertis EM ., PLoS Biol. May 1, 2004; 2 (5): E92.
Identification of a second Xenopus twisted gastrulation gene. , Oelgeschläger M , Tran U , Grubisic K, De Robertis EM ., Int J Dev Biol. February 1, 2004; 48 (1): 57-61.
Dorsal- ventral patterning and neural induction in Xenopus embryos. , De Robertis EM , Kuroda H ., Annu Rev Cell Dev Biol. January 1, 2004; 20 285-308.
Inactivation of mouse Twisted gastrulation reveals its role in promoting Bmp4 activity during forebrain development. , Zakin L, De Robertis EM ., Development. January 1, 2004; 131 (2): 413-24.
Integration of IGF, FGF, and anti-BMP signals via Smad1 phosphorylation in neural induction. , Pera EM , Ikeda A, Eivers E, De Robertis EM ., Genes Dev. December 15, 2003; 17 (24): 3023-8.