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Green Lab

Research Interests

Embryonic patterning and cell polarity

Research Area

My lab uses Xenopus frog embryos and sometimes zebrafish and cultured mammalian cells to investigate basic mechanisms in development. This includes the molecular mechanisms governing - Embryo and cell polarity, - Morphogen growth factor action (activin, Wnts) - Tissue morphogenesis - Signal transduction (GSK3, Wnts) - Differentiation of mesoderm and - Specification of neurons (neurogenesis) and ciliated cells Molecules of interest include the canonical and non-canonical Wnt pathways, the PAR polarity proteins, especially the kinases PAR1 and PAR4, atypical PKC and glycogen synthase kinase (GSK3). My group works within a lively Developmental Biology Department at the Guy's Hospital campus of King's College London with fabulous views over the heart of central London. We are beginning to apply our morphogen expertise to directed differentiation of embryonic stem cells.

Current Members

Green, Jeremy B. (Principal Investigator/Director)



Institution: King's College London

King's College London
Department of Craniofacial Development
Guy's Tower, Floor 27
SE1 9RT, United Kingdom

Personal Phone: +44 207 188 1794

General/Lab Fax: +44 207 188 1795

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